Database Registry for Neural Network Biomarkers in Psychosis

Part of paid clinical trials in Dallas, Texas.

Sponsor
University of Texas Southwestern Medical Center
Study ID
NCT01409109
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Accepted

Study Details

Several observations have been made with magnetic resonance imaging (MRI) that characterize brain connections and brain function in individuals with schizophrenia and other mental disorders. For example, research investigating schizophrenia focuses on the dysfunction of connections within and between the medial temporal lobe and the prefrontal cortex as well as other pertinent brain regions. This database registry will allow for the collection of clinical interview data, behavioral data, blood, magnetic resonance imaging (MRI) data, and functional magnetic resonance imaging (fMRI) data on individuals with and without mental disorders to better understand how connections in the brain and various brain regions function differently while volunteers perform various cognitive tasks. This is an observational study that is being conducted to collect data and place it in a registry for current and future investigational questions related to imaging in mental disorders.

Key Dates

Start date
Mar 31, 2010
Status verified
Apr 2026
Primary completion
Apr 30, 2029
Completion
Apr 30, 2029

Study Design

Enrollment
1,000 participants (estimated)

Arms

  • Arm: Patient volunteers
    This group is comprised of persons with Schizophrenia and Schizoaffective.
  • Arm: Healthy volunteers
    This group is comprised of individuals who have no current or past psychiatric diagnosis.

Primary Outcome Measure

Differences in hippocampal subfield activation between people with schizophrenia (or schizoaffective disorder) and healthy volunteers [ Time Frame: Participants will be assessed over the course of 4-6 weeks, until all study procedures are complete ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Texas Southwestern Medical CenterDallasTexas75390
Elena Ivleva, M.D., Ph.D.
[email protected]
214-645-8942
Debra Bushong, M.S., L.P.C.
[email protected]
214-648-4653
Carol A. Tamminga, M.D. (PRINCIPAL_INVESTIGATOR)
Elena Ivleva, M.D., Ph.D. (SUB_INVESTIGATOR)

Find similar trials in Dallas, TX

By condition
Schizophrenia
By specialty
PsychiatryMental healthBehavioral health
By research site
University of Texas Southwestern Medical Center· Dallas, TX

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