Oncology Clinical Trials in Evanston, IL
As of June 2026, 39 paid clinical trials are recruiting for Oncology in Evanston, Illinois. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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39 clinical trials for Oncology
·Clear filters·↓ Download CSVA Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
Falcon Real World Evidence Registry
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Fasting Mimicking Diet (FMD) in Conjunction With Chemotherapy in Advanced Ovarian Cancer
A Registry for People With Lung Cancer
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of EP0031 in Patients With Advanced RET-altered Malignancies
GEMINI-NSCLC: NSCLC Biomarker Study
Performance of Inherited Risk Assessment for Predicting Prostate Cancer From Prostate Biopsy
Precision-Based Genomics in Prostate Cancer
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
Pancreatic Cancer Early Detection Consortium
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Blue Light Cystoscopy With Cysview® Registry
About research studies in Evanston
Evanston has approximately 175 recruiting research studies across a wide range of therapeutic areas. Illinois's research base includes Northwestern Medicine, Rush University Medical Center, University of Chicago Medicine, and Ann & Robert H. Lurie Children's Hospital, covering oncology, cardiology, and pediatric specialties.
Top Research Study Locations in Evanston
Researchers run research studies in Evanston, IL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| NorthShore University HealthSystem-Evanston Hospital | Acute Myeloid Leukemia, Breast Cancer, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | 38 |
| Northwestern University | Hearing Loss, Sensorineural, Heart Failure, ALS | 35 |
| Endeavor Health | AAA - Abdominal Aortic Aneurysm, Air Leak From Lung, Aneurysm, Brain | 21 |
| NorthShore University HealthSystem | Prostate Cancer, Abdominal Hernia, Adverse Pregnancy Outcome | 21 |
| Northshore University Health System | Acute Myelogenous Leukemia, Bladder Cancer, Breast Cancer | 9 |
| Northshore University Healthsystem Research Institute | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 4 |
| Endeavor Health Evanston Hospital | Obesity and Obesity-related Medical Conditions, Perinatal Decision Making, Weight Loss | 2 |
| Evanston Hospital | Atrial Fibrillation, Dysmenorrhea, Intracerebral Hemorrhage | 2 |
| NorthShore University Health System Research Institute | Benign Prostatic Hyperplasia (BPH), Hernia, Diaphragmatic, Hernia, Hiatal | 2 |
| 01L_Northshore University Health System | Spinal Stenosis Lumbar | 1 |
| AMITA St. Francis Hospital | Lumbar Spinal Stenosis | 1 |
| Clinical Trial Site | Transthyretin Amyloidosis With Cardiomyopathy | 1 |
| Endeavor Health (NorthShore University HealthSystem) | Breastfeeding | 1 |
| Endeavor Health (Northshore University HealthSystem Research Institute) | Breast Reconstruction Surgery | 1 |
| Endeavor Health (Northshore) | DCIS, Ductal Breast Carcinoma In Situ, Stage 0 Breast Cancer | 1 |
| Endeavor Health - Evanston Hospital | Multiple Myeloma | 1 |
| Endeavor Health - Kellogg Cancer Center | Uterine Leiomyosarcoma | 1 |
| Endeavor Health - Northshore | Atrial Fibrillation (AF) | 1 |
| Endeavor Health Evanston Kellogg Cancer Care Center | Ovarian Cancer | 1 |
| Endeavor Health Glenbook Hosp | Acute Myocardial Infarction (AMI), Cardiovascular Risk | 1 |
| Endeavor Health Systems | Alzheimer Disease, Chronic Traumatic Encephalopathy | 1 |
| Endeavor Health, Northshore | Stroke Hemorrhagic | 1 |
| Evanston Hospital Northshore University Health System | Lumbar Spinal Stenosis | 1 |
| Evanston NorthShore University HealthSystem | Venous Thromboembolism | 1 |
| Investigative | Solid Tumors | 1 |
Active & Upcoming Studies in Evanston (2026)
Recruiting trials in Evanston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (64 active studies)
- The Implementation of Genetic Risk for Colorectal Cancer Screening · Endeavor Health
- A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201) · Phase 3 · Bristol-Myers Squibb
Neurology & pain (15 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Vaginal Sildenafil for Primary Dysmenorrhea · Phase 1 · Kevin Hellman
Cardiovascular (12 active studies)
Mental health & behavior (3 active studies)
- Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function · Northwestern University
- Sleep, Dreaming, and Virtual Reality for Mental Health · EARLY_Phase 1 · Northwestern University
Diabetes & metabolic (2 active studies)
Common conditions studied in Evanston
- Acute Myeloid Leukemia (5 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- ARDS (4 active studies). Recruiting ARDS studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- ARDS (Acute Respiratory Distress Syndrome) (4 active studies). Recruiting ARDS (Acute Respiratory Distress Syndrome) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Respiratory Distress Syndrome (4 active studies). Recruiting Acute Respiratory Distress Syndrome studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Respiratory Distress Syndrome (ARDS) (4 active studies). Recruiting Acute Respiratory Distress Syndrome (ARDS) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Atrial Fibrillation (4 active studies). Atrial fibrillation studies investigate next-generation anticoagulants, ablation technologies, and left atrial appendage closure devices.
Leading research sponsors in Evanston
- National Cancer Institute (NCI)
- Endeavor Health
- Northwestern University
- AstraZeneca
- NRG Oncology
Local regulations and guidelines
Clinical trials in Illinois are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Illinois studies must also comply with the Illinois Personal Information Protection Act (PIPA) and Biometric Information Privacy Act (BIPA) where applicable.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Evanston. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Evanston
Hipa.ai aggregates every recruiting study in Evanston from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Evanston?
There are approximately 175 recruiting clinical trials in Evanston, Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Evanston pay participants?
Most recruiting trials in Evanston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Evanston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Evanston?
The most common conditions under active study in Evanston include Acute Myeloid Leukemia (5), ARDS (4), ARDS (Acute Respiratory Distress Syndrome) (4), Acute Respiratory Distress Syndrome (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Evanston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Evanston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Evanston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Evanston?
Recruiting research sites in Evanston include NorthShore University HealthSystem-Evanston Hospital, Northwestern University, Endeavor Health, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Evanston right now?
The largest active categories in Evanston are Cancer & tumors (64), Neurology & pain (15), Cardiovascular (12). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.