Oncology Clinical Trials in Duarte, CA

As of June 2026, 306 paid clinical trials are recruiting for Oncology in Duarte, California. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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306 clinical trials for Oncology

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A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

for Solid Tumors

8 locations incl. Duarte

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07195916·Phase 1·Recruiting

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Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial

for Chronic Lymphocytic Leukemia

Drug: Epcoritamab

7 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07218510·Phase 2·Recruiting

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Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia

for Acute Lymphoblastic Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06735690·EARLY_Phase 1·Recruiting

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Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

for Hematopoietic and Lymphatic System Neoplasm

3 locations incl. Duarte

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT06817889·Phase 2·Recruiting

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A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

for Advanced Breast Cancer

9 locations incl. Duarte

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07318805·Phase 1·Recruiting

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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

117 locations incl. Anchorage

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting

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Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

for Clear Cell Renal Cell Carcinoma

10 locations incl. Duarte

Sponsor: Neomorph, Inc

Sex: All·Age: 18+

Code: NCT07300241·Phase 1·Recruiting

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Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for Non-small Cell Lung Cancer

70 locations incl. Phoenix

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06686771·Phase 3·Recruiting

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Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

29 locations incl. Anchorage

Sponsor: Incyte Corporation

Sex: Female·Age: 18+

Code: NCT07214779·Phase 3·Recruiting

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A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

for Biliary Tract Cancer

Drug: Rilvegostomig

33 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07221253·Phase 3·Recruiting

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A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

for Advanced Solid Tumors

6 locations incl. Duarte

Sponsor: SEED Therapeutics, Inc.

Sex: All·Age: 16+

Code: NCT07197554·Phase 1·Recruiting

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First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

for Esophageal Squamous Cell Carcinoma

10 locations incl. Scottsdale

Sponsor: Plexium, Inc.

Sex: All·Age: 18+

Code: NCT07284186·Phase 1·Recruiting

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A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

29 locations incl. Goodyear

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07213674·Phase 3·Recruiting

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A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

for SST2-positive Neuroendocrine Neoplasms

20 locations incl. Phoenix

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07129252·Phase 1, Phase 2·Recruiting

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Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R)

for Prostate Cancer

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: Male·Age: 18+

Code: NCT07210086·Phase 2·Recruiting

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Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.

for Esophageal Cancer

14 locations incl. Cerritos

Sponsor: SOFIE

Sex: All·Age: 18+

Code: NCT07217704·Phase 3·Recruiting

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

50 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting

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Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

for Metastatic Malignant Solid Neoplasm

3 locations incl. Duarte

Sponsor: Anusha Kalbasi

Sex: All·Age: 18 - 75

Code: NCT04119024·Phase 1·Recruiting

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A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for Breast Cancer

Drug: Giredestrant

16 locations incl. Duarte

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT07100106·Phase 1, Phase 2·Recruiting

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Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

for Breast Carcinoma

2 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06731894·Phase 2·Recruiting

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LTFU for All Cell and Gene Therapy Studies

for Hepatocellular Carcinoma

18 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06194461·Not Yet Recruiting

A Long Term Follow-up Study of TScan TCR-T Products

for AML

2 locations incl. Duarte

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18 - 110

Code: NCT06976736·Recruiting

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64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

for Metastatic Sarcoma

5 locations incl. Duarte

Sponsor: Lantheus Medical Imaging

Sex: All·Age: 15+

Code: NCT06298916·Phase 1, Phase 2·Recruiting

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External Beam Radiation Therapy in Combination With Talquetamab for the Treatment of Multiple Myeloma Patients With Extramedullary Disease

for Extramedullary Disease in Multiple Myeloma

Drug: Talquetamab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06572605·Phase 1, Phase 2·Recruiting

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Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

7 locations incl. Arcadia

Sponsor: City of Hope Medical Center

Sex: Female·Age: 40+

Code: NCT06954831·Phase 2·Recruiting

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Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for PIK3CA Mutation

51 locations incl. Gilbert

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06982521·Phase 3·Recruiting

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Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Drug: Sonrotoclax

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06859008·Phase 1·Recruiting

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A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for Urothelial Carcinoma Bladder

9 locations incl. Duarte

Sponsor: Aktis Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07020117·Phase 1·Recruiting

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A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

for Advanced/Metastatic Solid Tumors

21 locations incl. Duarte

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07090499·Phase 1·Recruiting

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A Dose Randomization Study of Bulumtatug Fuvedotin in TNBC Patients Previously Treated With ADCs

for Triple Negative Breast Cancer

6 locations incl. Duarte

Sponsor: Mabwell (Shanghai) Bioscience Co., Ltd.

Sex: All·Age: 18+

Code: NCT06908928·Phase 1·Recruiting

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A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for Breast Neoplasms

16 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07114601·Phase 1·Recruiting

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A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

for Multiple Myeloma

13 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07073547·Phase 1·Recruiting

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A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for Recurrent Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06763341·Phase 1·Recruiting

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A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

for Follicular Lymphoma

Drug: Golcadomide

31 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT06911502·Phase 3·Recruiting

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A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

for AML (Acute Myelogenous Leukemia)

13 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 18 - 66

Code: NCT06859424·Phase 2·Recruiting

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Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

for Breast Cancer

22 locations incl. Duarte

Sponsor: Celcuity Inc

Sex: All·Age: 18+

Code: NCT06757634·Phase 3·Recruiting

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Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting

for Hematopoietic and Lymphatic System Neoplasm

2 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07126301·Recruiting

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225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

for Acute Lymphoblastic Leukemia

Drug: Daratumumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06287944·Phase 1·Recruiting

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A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer

for Breast Cancer

134 locations incl. Daphne

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06966453·Phase 1, Phase 2·Recruiting

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PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV)

for Hematologic Malignancies

11 locations incl. Duarte

Sponsor: Pulmotect, Inc.

Sex: All·Age: 18+

Code: NCT06665100·Phase 2·Recruiting

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Conditions in Oncology (Duarte, CA)

Solid tumor· 48 Non-small cell lung cancer (NSCLC)· 35 Acute myeloid leukemia (AML)· 32 Myelodysplastic syndromes (MDS)· 28 Breast cancer· 26 Hematologic malignancy· 25 Colorectal cancer· 21 Prostate cancer· 20 Pancreatic cancer· 18 Ovarian cancer· 18 Non-Hodgkin lymphoma· 16 Metastatic breast cancer· 15 Cancer (any)· 15 Gastric cancer· 14 Esophageal cancer· 14 Multiple myeloma· 14 Endometrial cancer· 12 Acute lymphoblastic leukemia· 12 Head and neck cancer· 12 Leukemia (other)· 11 Diffuse large B-cell lymphoma (DLBCL)· 11 Bladder cancer· 9 Chronic lymphocytic leukemia (CLL)· 9 Mantle cell lymphoma· 9 Kidney cancer· 8 Myelofibrosis· 8 Lung cancer· 7 Gastroesophageal junction cancer· 7 Biliary tract cancer· 7 Cervical cancer· 7 Hodgkin lymphoma· 7 Small lymphocytic lymphoma· 7 Melanoma· 7 Triple-negative breast cancer· 6 Liver cancer· 5 Myeloproliferative neoplasm· 5 Follicular lymphoma· 5 Sarcoma· 5 Metastatic prostate cancer· 4 Marginal zone lymphoma· 4 Neuroendocrine tumors· 4 Metastatic colorectal cancer· 3 Colon cancer· 3 Fallopian tube cancer· 3 Chronic myelomonocytic leukemia· 3 Small cell lung cancer· 2 Glioblastoma· 2 Thyroid cancer· 2 Osteosarcoma· 2 Ewing sarcoma· 2 HER2-positive breast cancer· 1 HER2-negative breast cancer· 1 Brain cancer· 1 Brain metastases· 1 Burkitt lymphoma· 1 Neuroblastoma· 1 Mesothelioma· 1