Oncology Clinical Trials in Denver, CO
As of June 2026, 183 paid clinical trials are recruiting for Oncology in Denver, Colorado. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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183 clinical trials for Oncology
·Clear filters·↓ Download CSVA Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer
A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Phase 1 Study of PF-08046033 in Advanced Solid Tumors
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors
A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors
A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)
A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
A Novel Patient Decision Aid for Surgical Treatment Options in Early-Stage Breast Cancer
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion Alone or in Combination With Oral, IV, Subcutaneous Daratumumab; Lenalidomide; Dexamethasone; Carfilzomib
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
The Vanguard Study: Testing a New Way to Screen for Cancer
High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer
A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas
Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)
About research studies in Denver
Denver has approximately 561 recruiting research studies across a wide range of therapeutic areas. Colorado hosts the University of Colorado Anschutz Medical Campus, National Jewish Health, and Children's Hospital Colorado, with strong programs in pulmonology, oncology, and cardiovascular research.
Top Research Study Locations in Denver
Researchers run research studies in Denver, CO at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Colorado Blood Cancer Institute | Multiple Myeloma, Acute Myeloid Leukemia, Non-Hodgkin Lymphoma | 64 |
| National Jewish Health | Cystic Fibrosis, Asthma, Cystic Fibrosis (CF) | 46 |
| AdventHealth Porter | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 31 |
| Sarah Cannon Research Institute at HealthONE | Advanced Solid Tumor, Solid Tumor, Advanced Cancer | 29 |
| Rocky Mountain Cancer Centers-Midtown | Malignant Solid Neoplasm, Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 23 |
| Rocky Mountain Cancer Centers-Rose | Malignant Solid Neoplasm, Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 23 |
| Presbyterian - Saint Lukes Medical Center - Health One | Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8, Chronic Lymphocytic Leukemia | 22 |
| The Women's Imaging Center | Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8, Chronic Lymphocytic Leukemia | 22 |
| Rocky Mountain Cancer Centers | Breast Cancer, Colorectal Neoplasms, Breast Neoplasms | 17 |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Metastatic Osteosarcoma | 17 |
| Kaiser Permanente-Franklin | Breast Carcinoma, Anatomic Stage II Breast Cancer AJCC v8, Colorectal Carcinoma | 16 |
| UCHealth - Cherry Creek | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Muscle Invasive Bladder Urothelial Carcinoma | 16 |
| University of Colorado | B Cell Lymphoma, B-Cell Non-Hodgkin's Lymphoma, CADASIL | 16 |
| Rose Medical Center | Chronic Lymphocytic Leukemia, Malignant Solid Neoplasm, Melanoma | 15 |
| Denver Health Medical Center | Acute Respiratory Failure, Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder) | 13 |
| Saint Joseph Hospital - Cancer Centers of Colorado | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 13 |
| National Jewish Health-Main Campus | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 11 |
| Denver Health and Hospital Authority | Sepsis, ARDS, Acute Otitis Media | 10 |
| Cancer Center of Colorado at Sloan's Lake | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 10 |
| University of Colorado Denver | Amyotrophic Lateral Sclerosis, Attention, Behavioral Variant Frontotemporal Dementia (bvFTD) | 10 |
| Western Surgical Care | Chronic Lymphocytic Leukemia, Malignant Solid Neoplasm, Melanoma | 10 |
| Rocky Mountain Cancer Centers, LLP | Colorectal Neoplasms, Urothelial Cancer, Advanced Renal Cell Carcinoma | 9 |
| Children's Hospital Colorado | ALL, AML, Acute Respiratory Distress Syndrome | 8 |
| Sarah Cannon Research Institute | Gastric Cancer, Locally Advanced or Metastatic Solid Tumors, Pancreatic Cancer | 7 |
| Porter Adventist Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Bone Cancer, NOS, Breast Cancer, NOS | 6 |
Active & Upcoming Studies in Denver (2026)
Recruiting trials in Denver grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (249 active studies)
- Trial to Evaluate an Educational Video Series for Women in Breast Cancer Treatment · University of Colorado, Denver
- A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 ) · Phase 1 · Eli Lilly and Company
Cardiovascular (18 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Optimal Ventilation for Cardiac Arrest · Children's Hospital of Philadelphia
Diabetes & metabolic (10 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
Mental health & behavior (9 active studies)
- Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder · Phase 3 · Vanda Pharmaceuticals
- Occupational Therapy for Mental Health and Engagement in Neurorehabilitation · Colorado State University
Neurology & pain (8 active studies)
- CF Wellness Program · Johns Hopkins University
- A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101 · Kyverna Therapeutics
Pediatric (6 active studies)
- Meet Me on the Pitch: Developing and Testing a Community-Based Sports and Behavioral Health Intervention for Youth · University of California, San Francisco
- Interventions to De-implement Unnecessary Antibiotic Prescribing for Children With Ear Infections · Intermountain Health Care, Inc.
HIV / STI (4 active studies)
- Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention · Gilead Sciences
- A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062) · Phase 2, Phase 3 · Merck Sharp & Dohme LLC
Eye & vision (4 active studies)
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
- A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK · Phase 3 · Kodiak Sciences Inc
Vaccines (3 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia. · Phase 2 · Vasomune Therapeutics, Inc.
Common conditions studied in Denver
- Breast Cancer (20 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Multiple Myeloma (16 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumor (15 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Solid Tumor (11 active studies). Recruiting Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cystic Fibrosis (10 active studies). Recruiting Cystic Fibrosis studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Endometrial Cancer (10 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Denver
- University of Colorado, Denver
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- SWOG Cancer Research Network
Local regulations and guidelines
Clinical trials in Colorado are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Colorado trials are additionally subject to the Colorado Privacy Act (CPA), which adds consumer data-protection requirements to federal baseline standards.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Denver. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Denver
Hipa.ai aggregates every recruiting study in Denver from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Denver?
There are approximately 561 recruiting clinical trials in Denver, Colorado listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Denver pay participants?
Most recruiting trials in Denver compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Denver?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Denver?
The most common conditions under active study in Denver include Breast Cancer (20), Multiple Myeloma (16), Advanced Solid Tumor (15), Solid Tumor (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Denver?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Denver on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Denver?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Denver?
Recruiting research sites in Denver include Colorado Blood Cancer Institute, National Jewish Health, AdventHealth Porter, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Denver right now?
The largest active categories in Denver are Cancer & tumors (249), Cardiovascular (18), Diabetes & metabolic (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.