Paid Clinical Trials in Lone Tree, CO
As of June 2026, 102 paid clinical trials are recruiting in Lone Tree, Colorado. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Lone Tree offers studies at sites including Rocky Mountain Cancer Centers-Sky Ridge for conditions such as Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm, Breast Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Lone Tree
Trials by drug in Lone Tree
Filter results
102 clinical trials
↓ Download CSVHearing Outcomes With the Nucleus® 8 Sound Processor and Nucleus® 7 Sound Processor in Adult Veteran and Non-veteran Cochlear Implant Recipients
Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
The Vanguard Study: Testing a New Way to Screen for Cancer
A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures
Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer
A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)
Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma
Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients
A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma
A Phase 1/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia (CARDINAL)
Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
About research studies in Lone Tree
Lone Tree has approximately 102 recruiting research studies across a wide range of therapeutic areas. Colorado hosts the University of Colorado Anschutz Medical Campus, National Jewish Health, and Children's Hospital Colorado, with strong programs in pulmonology, oncology, and cardiovascular research.
Top Research Study Locations in Lone Tree
Researchers run research studies in Lone Tree, CO at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Rocky Mountain Cancer Centers-Sky Ridge | Malignant Solid Neoplasm, Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 24 |
| UCHealth Lone Tree Health Center | Anatomic Stage II Breast Cancer AJCC v8, Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8 | 17 |
| Kaiser Permanente-Lone Tree | Breast Carcinoma, Anatomic Stage II Breast Cancer AJCC v8, Colorectal Carcinoma | 15 |
| Rocky Mountain Cancer Centers, LLP | Breast Cancer, Colorectal Neoplasms, Advanced/Metastatic Urothelial Cancer | 12 |
| Sky Ridge Medical Center | Chronic Lymphocytic Leukemia, Malignant Solid Neoplasm, Melanoma | 11 |
| Rocky Mountain Cancer Centers | Advanced/Metastatic Solid Tumors, Carcinoma, Non-Small Cell Lung, Carcinoma, Non-Small-Cell Lung | 5 |
| Colorado Center for Reproductive Medicine | Infertility, AMH, Healthy | 3 |
| Lone Tree Medical Center | Breast Cancer, Carcinoma, Non-Small-Cell Lung, Inferior Vena Cava Thrombosis | 3 |
| UCHealth Lone Tree Medical Center | Breast Cancer, Breast Cancer and Pregnancy, Implementation Strategy Bundles for Structured Follow-up | 2 |
| University of Colorado Health - Lone Tree Medical Center | Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostate Cancer Metastatic, Prostatic Neoplasms | 2 |
| Urology Associates of Denver | Non-Muscle Invasive Bladder Neoplasms, Non-muscle Invasive Bladder Cancer | 2 |
| BEAUTY by BUFORD | Post Procedural Erythema, Capsular Contracture Associated With Breast Implant, Capsular Contracture Grade III | 2 |
| Rocky Mountain Cancer Centers (RMCC) | Colon Adenocarcinoma, Rectal Adenocarcinoma, Lung Neoplasm Malignant | 2 |
| Rocky Mountain Cancer Centers - Lone Tree | Non Small Cell Lung Carcinoma, Multiple Myeloma | 2 |
| 003 | Advanced Solid Tumor | 1 |
| Centeno-Schultz Clinic | Degenerative Disc Disease | 1 |
| Clinical Study Site | Non-Small Cell Lung Cancer | 1 |
| Denver Research and Technology Lab | Hearing Loss | 1 |
| Denver Research and Technology Labs | Hearing Loss | 1 |
| Institute of Esophageal and Reflux Surgery | Large Hiatal Hernia, Paraesophageal Hernia | 1 |
| Peak Gastroenterology Surgery Center | Moderately to Severely Active Crohns Disease | 1 |
| Rocky Mountain Cancer | Non-Small Cell Lung Cancer | 1 |
| Rocky Mountain Cancer Centers LLP | Breast Cancer | 1 |
| Rocky Mountain Cancer Centers, LLP - Oncology | Advanced Solid Tumor, Malignant Peripheral Nerve Sheath Tumors, Mesothelioma | 1 |
| Rocky Mountain Kidney Care - Lone Tree | Chronic Kidney Disease, Receiving Dialysis, Dialysis, ESRD (End-Stage Renal Disease) | 1 |
Active & Upcoming Studies in Lone Tree (2026)
Recruiting trials in Lone Tree grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (76 active studies)
- Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer · Phase 2, Phase 3 · Pfizer
- Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer · Phase 1, Phase 2 · Pfizer
Diabetes & metabolic (1 active study)
- PATHWEIGH: Pragmatic Weight Management in Primary Care · University of Colorado, Denver
Common conditions studied in Lone Tree
- Breast Cancer (7 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Malignant Solid Neoplasm (4 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Carcinoma (3 active studies). Recruiting Breast Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Carcinoma, Non-Small-Cell Lung (3 active studies). Recruiting Carcinoma, Non-Small-Cell Lung studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Infertility (3 active studies). Fertility research evaluates new IVF protocols, ovarian reserve preservation, hormone-modulating therapies, and treatments for endometriosis and menopause.
Leading research sponsors in Lone Tree
- Alliance for Clinical Trials in Oncology
- NRG Oncology
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- University of Colorado, Denver
Local regulations and guidelines
Clinical trials in Colorado are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Colorado trials are additionally subject to the Colorado Privacy Act (CPA), which adds consumer data-protection requirements to federal baseline standards.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Lone Tree. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Lone Tree
Hipa.ai aggregates every recruiting study in Lone Tree from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Lone Tree?
There are approximately 102 recruiting clinical trials in Lone Tree, Colorado listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Lone Tree pay participants?
Most recruiting trials in Lone Tree compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Lone Tree?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Lone Tree?
The most common conditions under active study in Lone Tree include Breast Cancer (7), Anatomic Stage II Breast Cancer AJCC v8 (4), Malignant Solid Neoplasm (4), Breast Carcinoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Lone Tree?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Lone Tree on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Lone Tree?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Lone Tree?
Recruiting research sites in Lone Tree include Rocky Mountain Cancer Centers-Sky Ridge, UCHealth Lone Tree Health Center, Kaiser Permanente-Lone Tree, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Lone Tree right now?
The largest active categories in Lone Tree are Cancer & tumors (76), Diabetes & metabolic (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.