Paid Clinical Trials in Connecticut

Connecticut has 1,385 paid clinical trials enrolling now across cities including New Haven, Hartford and Stamford. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,385 clinical trials

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Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors

for Melanoma

3 locations incl. New Haven

Sponsor: IO Biotech

Sex: All·Age: 18+

Code: NCT05280314·Phase 2·Recruiting

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A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

91 locations incl. Huntsville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06119581·Phase 3·Recruiting

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The Effect of Body Position on Oropharyngeal Swallow Function in Infants

for Aspiration

1 location in Hartford

Sponsor: Connecticut Children's Medical Center

Sex: All·Age: 38 Weeks - 56 Weeks·Accepts healthy volunteers

Code: NCT05874102·Enrolling By Invitation

Sipuleucel-T Combined With Bipolar Androgen Therapy in Men With mCRPC

for Metastatic Castration-resistant Prostate Cancer

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06100705·Phase 2·Recruiting

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A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

for Metastatic Castration-resistant Prostate Cancer (mCRPC)

62 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06136650·Phase 3·Recruiting

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AMPK-activation by Metformin in FSGS: AMP-FSGS

for Focal Segmental Glomerulosclerosis

2 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 80

Code: NCT06090227·Phase 1, Phase 2·Recruiting

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Physiologic Markers of Cardiometabolic Risk in People With Type 1 Diabetes

for type1diabetes

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 18 - 30

Code: NCT06105931·Phase 1·Recruiting

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MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

38 locations incl. Tucson

Sponsor: Intellia Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06128629·Phase 3·Recruiting

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A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

for Chronic Lymphocytic Leukemia

Drug: Nemtabrutinib

43 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06136559·Phase 3·Recruiting

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Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery

for Cervical Spine Fusion

1 location in Hartford

Sponsor: Hartford Hospital

Sex: All·Age: 40 - 80

Code: NCT05996133·Phase 4·Recruiting

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A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

23 locations incl. Tucson

Sponsor: Eikon Therapeutics

Sex: All·Age: 18 - 89

Code: NCT06253130·Phase 1, Phase 2·Recruiting

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A Study of ATG-031 in Advanced Solid Tumors or B-cell Non-Hodgkin Lymphomas

for Advanced Solid Tumors

4 locations incl. San Francisco

Sponsor: Antengene Biologics Limited

Sex: All·Age: 18+

Code: NCT06028373·Phase 1·Recruiting

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Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation

for Kidney Transplant

15 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT05917522·Phase 2·Recruiting

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Etomidate Versus Propofol in CABG Surgery

for Coronary Artery Disease

1 location in Hartford

Sponsor: Hartford Hospital

Sex: All·Age: 18 - 90

Code: NCT06068764·Phase 4·Recruiting

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Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

for Breast Cancer

79 locations incl. Phoenix

Sponsor: BriaCell Therapeutics Corporation

Sex: All·Age: 18+

Code: NCT06072612·Phase 3·Recruiting

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Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

for Lung Carcinoma

16 locations incl. Davis

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06196008·Recruiting

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Endometriosis and Microvascular Dysfunction; Simvastatin and Duavee

for Endometriosis

1 location in New Haven

Sponsor: Penn State University

Sex: Female·Age: 18 - 45

Code: NCT05059626·Phase 4·Recruiting

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A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for NASH With Fibrosis

Drug: Efruxifermin

205 locations incl. Birmingham

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06215716·Phase 3·Recruiting

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Target ADHD Executive Working Memory Replication Study

for ADHD

1 location in Hartford

Sponsor: Hartford Hospital

Sex: All·Age: 12 - 18·Accepts healthy volunteers

Code: NCT06446284·Recruiting

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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

69 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting

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Supporting Parents in Affirming Their Children's Experiences of Stigma

for Parent-Child Relations

3 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 15+

Code: NCT05919849·Phase 1·Recruiting

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Evaluation of the GORE® Ascending Stent Graft

for Aortic Aneurysm, Thoracic

41 locations incl. Birmingham

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05800743·Enrolling By Invitation

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for Lung Cancer Diagnosis

36 locations incl. Los Angeles

Sponsor: Freenome Holdings Inc.

Sex: All·Age: 50+

Code: NCT06122077·Recruiting

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A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

for Locally Advanced Solid Tumors

Drug: Atezolizumab

6 locations incl. Birmingham

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06031441·Phase 1·Recruiting

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Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Durvalumab

536 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06058377·Phase 3·Recruiting

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A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

for Breast Cancer

Drug: Durvalumab

64 locations incl. Daphne

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06103864·Phase 3·Recruiting

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A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

for Hematologic Malignancy

17 locations incl. Duarte

Sponsor: CRISPR Therapeutics AG

Sex: All·Age: 18+

Code: NCT06208878·Enrolling By Invitation

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

23 locations incl. Palo Alto

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting

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Managing Anxiety in Pediatric Primary Care (MAPP)

for Anxiety

1 location in West Hartford

Sponsor: UConn Health

Sex: All·Age: 6 - 17·Accepts healthy volunteers

Code: NCT06104904·Recruiting

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Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance

for Non-muscle-invasive Bladder Cancer

9 locations incl. West Haven

Sponsor: White River Junction Veterans Affairs Medical Center

Sex: All·Age: 18+

Code: NCT05796375·Phase 2·Recruiting

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The PEERLESS II Study

for Pulmonary Embolism

50 locations incl. Birmingham

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06055920·Recruiting

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A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

for Obesity

49 locations incl. Chandler

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT06143956·Phase 2·Recruiting

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

25 locations incl. Phoenix

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting

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OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

47 locations incl. Tucson

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06016738·Phase 3·Recruiting

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Transcutaneous Electrical Nerve Stimulation (TENS) and Low Back Pain

for Chronic Low-back Pain

1 location in West Hartford

Sponsor: University of Hartford

Sex: All·Age: 18 - 60

Code: NCT05812885·Recruiting

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A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

for Secondary Progressive Multiple Sclerosis

Drug: Foralumab

7 locations incl. North Haven

Sponsor: Tiziana Life Sciences LTD

Sex: All·Age: 18 - 75

Code: NCT06292923·Phase 2·Recruiting

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Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for Hereditary Hemorrhagic Telangiectasia

16 locations incl. Birmingham

Sponsor: Cure HHT

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06259292·Recruiting

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Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

for Neovascular Age-related Macular Degeneration

63 locations incl. Glendale

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05904028·Phase 3·Recruiting

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Investigating the Mu:Kappa Opioid Receptor Imbalance in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 21 - 70·Accepts healthy volunteers

Code: NCT05957159·EARLY_Phase 1·Recruiting

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Systems Investigation of Vaccine Responses in Aging and Frailty

for Influenza

1 location in New Haven

Sponsor: Yale University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT05291676·Phase 2·Recruiting

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