Blood cancer Clinical Trials in Columbus, OH

As of June 2026, 92 paid clinical trials are recruiting for Blood cancer in Columbus, Ohio. Blood cancer trials investigate CAR-T cell therapies, bispecific antibodies, BTK and BCL-2 inhibitors, and novel combinations across leukemias, lymphomas, myeloma, and myelodysplastic syndromes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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92 clinical trials for Blood cancer

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Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

237 locations incl. Little Rock

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 60+

Code: NCT05976763·Phase 3·Recruiting

Apply to this trial

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

for Triple Negative Breast Cancer

Drug: Cemiplimab

9 locations incl. Los Angeles

Sponsor: OncoNano Medicine, Inc.

Sex: All·Age: 18+

Code: NCT06022029·Phase 1·Recruiting

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Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

1 location in Columbus

Sponsor: Seema Bhat

Sex: All·Age: 18+

Code: NCT05417165·Phase 2·Recruiting

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Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial

for Hematopoietic and Lymphoid System Neoplasm

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06314672·Recruiting

Apply to this trial

Weighted Blanket Use to Reduce Anxiety in Oncology Patients

for Hematopoietic and Lymphoid Cell Neoplasm

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06089408·Recruiting

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

44 locations incl. Phoenix

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting

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Epcoritamab and Rituximab for First-line Follicular Lymphoma

for Follicular Lymphoma

Drug: Epcoritamab

6 locations incl. Boston

Sponsor: Reid Merryman, MD

Sex: All·Age: 18+

Code: NCT05783609·Phase 2·Recruiting

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Study of SGR-1505 in Mature B-Cell Neoplasms

for Mature B-Cell Neoplasm

16 locations incl. Gilbert

Sponsor: Schrödinger, Inc.

Sex: All·Age: 18+

Code: NCT05544019·Phase 1·Recruiting

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Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

for Hematopoietic and Lymphoid Cell Neoplasm

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05178472·Recruiting

Apply to this trial

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

for Hematologic Malignancy

29 locations incl. Los Angeles

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 - 21

Code: NCT05476770·Phase 1·Recruiting

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A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Drug: Daratumumab

67 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05552222·Phase 3·Recruiting

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

45 locations incl. Phoenix

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting

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Acalabrutinib in Combination With Venetoclax or Obinutuzumab for the Treatment of Treatment-naive Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05336812·Phase 2·Recruiting

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IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)

for Acute Myeloid Leukemia

3 locations incl. Chapel Hill

Sponsor: Alice Mims

Sex: All·Age: 18+

Code: NCT05401097·Phase 2·Recruiting

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

42 locations incl. Phoenix

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

746 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting

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A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Patients With Multiple Myeloma That is Resistant to Current Standard of Care Treatments

for Multiple Myeloma

Drug: Linvoseltamab

13 locations incl. La Jolla

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05137054·Phase 1·Recruiting

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Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for Myelofibrosis

22 locations incl. Duarte

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT05320198·Phase 1, Phase 2·Recruiting

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Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

for Non Hodgkin Lymphoma

8 locations incl. Chicago

Sponsor: Newave Pharmaceutical Inc

Sex: All·Age: 13+

Code: NCT04771572·Phase 1·Recruiting

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

164 locations incl. Birmingham

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting

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A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

Drug: Mosunetuzumab

5 locations incl. Rochester

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT05091424·Phase 1·Recruiting

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A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

for Leukemia, Myeloid, Acute

33 locations incl. Newport Beach

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 12+

Code: NCT04988555·Phase 1, Phase 2·Recruiting

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Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

5 locations incl. Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05145400·Phase 2·Recruiting

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Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Relapsed/Refractory AML

for Acute Myeloid Leukemia

1 location in Columbus

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 24

Code: NCT05503134·Phase 1, Phase 2·Recruiting

Apply to this trial

Polatuzumab Vedotin in Combination With Chemotherapy in Subjects With Richter's Transformation

for Richter Syndrome

Drug: Polatuzumab Vedotin

4 locations incl. New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT04679012·Phase 2·Recruiting

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Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

13 locations incl. Phoenix

Sponsor: Michael Pulsipher

Sex: All·Age: 0 - 25

Code: NCT04836390·Phase 2·Enrolling By Invitation

Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

for CLL/SLL

4 locations incl. Durham

Sponsor: Newave Pharmaceutical Inc

Sex: All·Age: 18+

Code: NCT04775745·Phase 1·Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

621 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

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A Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma

for B-cell Non Hodgkin Lymphoma

10 locations incl. Tampa

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT04594642·Phase 1·Recruiting

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Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction

for Blasts More Than 5 Percent of Bone Marrow Nucleated Cells

2 locations incl. Sacramento

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18 - 75

Code: NCT04049539·Phase 1, Phase 2·Recruiting

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A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

for Myelodysplastic Syndrome

49 locations incl. Birmingham

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04227847·Phase 1·Recruiting

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

for Myelodysplastic Syndromes

Drug: Venetoclax

24 locations incl. Los Angeles

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT04256317·Phase 2, Phase 3·Recruiting

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Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

for Acute Myeloid Leukemia

2 locations incl. Westwood

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18 - 65

Code: NCT03533816·Phase 1·Recruiting

Apply to this trial

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for Myelofibrosis

32 locations incl. Birmingham

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT04176198·Phase 1, Phase 2·Recruiting

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A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia

Drug: Revumenib

22 locations incl. Duarte

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 30 Days+

Code: NCT04065399·Phase 1, Phase 2·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

for Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome

Drug: Ruxolitinib

3 locations incl. Columbus

Sponsor: Jennifer Saultz

Sex: All·Age: 18+

Code: NCT03874052·Phase 1·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

Apply to this trial

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

for Acute Myeloid Leukemia

11 locations incl. Duarte

Sponsor: Orca Biosystems, Inc.

Sex: All·Age: 12 - 78

Code: NCT03802695·Phase 1·Recruiting

Apply to this trial

Conditions in Blood cancer (Columbus, OH)

Acute myeloid leukemia (AML)· 26 Chronic lymphocytic leukemia (CLL)· 17 Multiple myeloma· 15 Myelodysplastic syndromes (MDS)· 13 Hematologic malignancy· 12 Non-Hodgkin lymphoma· 11 Leukemia (other)· 10 Follicular lymphoma· 10 Small lymphocytic lymphoma· 10 Diffuse large B-cell lymphoma (DLBCL)· 9 Mantle cell lymphoma· 9 Acute lymphoblastic leukemia· 5 Myelofibrosis· 5 Chronic myelomonocytic leukemia· 4 Marginal zone lymphoma· 4 Hodgkin lymphoma· 3 Myeloproliferative neoplasm· 2 Burkitt lymphoma· 2