LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)
for Glioma
5 locations incl. Baltimore
Sponsor: University of Maryland, Baltimore
Sex: All·Age: 18+
Code: NCT04699773·Recruiting
Glioblastoma Clinical Trials in Columbia, MD
As of June 2026, 2 paid clinical trials are recruiting for Glioblastoma in Columbia, Maryland. Glioblastoma studies investigate tumor-treating fields, targeted small molecules, and immunotherapy combinations for this aggressive brain cancer. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Columbia
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2 clinical trials for Glioblastoma
·Clear filters·↓ Download CSVLITT Followed by Hypofractionated RT for Recurrent Gliomas
for Glioblastoma
4 locations incl. Baltimore
Sponsor: University of Maryland, Baltimore
Sex: All·Age: 22+
Code: NCT04181684·Recruiting
About research studies in Columbia
Columbia has approximately 80 recruiting research studies across a wide range of therapeutic areas. Maryland hosts Johns Hopkins Medicine and the NIH Clinical Center in Bethesda, giving participants access to some of the most advanced early-phase research in the country.
Top Research Study Locations in Columbia
Researchers run research studies in Columbia, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Central Maryland Radiation Oncology in Howard County | Metastatic Malignant Neoplasm in the Brain, Metastatic Renal Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | 10 |
| Centennial Medical Group | Obesity, Overweight, Atherosclerotic Cardiovascular Disease (ASCVD) | 6 |
| Central Maryland Radiation Oncology | Brain Tumor, Glioblastoma, Glioma | 5 |
| Maryland Oncology Hematology, P.A. | Breast Cancer, Esophageal Adenocarcinoma, Gastroesophageal Junction Cancer | 5 |
| Johns Hopkins University | Atherosclerotic Cardiovascular Disease, Atherosclerotic Cardiovascular Disease (ASCVD), Cardiovascular Disease | 4 |
| Maryland Oncology Hematology | Breast Cancer, Colon Cancer, Colorectal Cancer | 4 |
| MedStar Health Research Institute | Degenerative Disc Disease, Leg Pain and/or Back Pain, Rotator Cuff Tear | 3 |
| Central Maryland Oncology Center | Breast Cancer, Breast Cancer Female | 2 |
| Erlanger Health System | AChR-Ab Seropositive Generalized Myasthenia Gravis, CIDP, CIDP - Chronic Inflammatory Demyelinating Polyneuropathy | 2 |
| Kailera Clinical Site | Obesity, Obesity With Diabetes, Overweight | 2 |
| Maryland Oncology Hematology - Columbia | Carcinoma, Non-Small-Cell Lung, Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung (NSCLC) | 2 |
| Anxiety Treatment Center of Maryland | Anxiety Disorder of Childhood | 1 |
| Baxis | Bacterial Conjunctivitis | 1 |
| Centennial Medical Group (CMG) | HOMA-IR, Mobility Disability, Obesity & Overweight | 1 |
| Centennial Medical Group Research Department | OSA | 1 |
| Charter Professional Center | Arthroplasty Complications, Fragility Fracture, Osteoporosis | 1 |
| Clearway Pain Solutions - Columbia | Lumbar Spinal Stenosis | 1 |
| Foundation Fighting Blindness | Achromatopsia, Bardet-Biedl Syndrome, Bassen-Kornzweig Syndrome | 1 |
| GSK Investigational Site | Neoplasms, Head and Neck | 1 |
| Galderma Investigational | Atopic Dermatitis | 1 |
| Johns Hopkins Community Physicians, Howard County Pediatrics | Adolescent Alcohol Use | 1 |
| Johns Hopkins Howard County Operating Room | Lumbar Spinal Stenosis | 1 |
| Johns Hopkins Surgery Centr- Howard County | Lumbar Spinal Stenosis | 1 |
| KUR Research @ Columbia | Obesity and Overweight | 1 |
| KUR Research at CMP | Diabetes Mellitus, Type 2, Metabolic Syndrome, PreDiabetes | 1 |
Active & Upcoming Studies in Columbia (2026)
Recruiting trials in Columbia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (35 active studies)
- A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer · Phase 2, Phase 3 · Pfizer
- GCCC 2578 Randomized Photon vs Proton RT for Newly Diagnosed Gynecologic Primaries · Phase 2 · University of Maryland, Baltimore
Diabetes & metabolic (8 active studies)
- Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss · Phase 2 · Veru Inc.
- A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes · Phase 3 · Hoffmann-La Roche
Vaccines (2 active studies)
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
- A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023) · Phase 3 · Merck Sharp & Dohme LLC
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Efficacy Trial of the CALM Intervention · UConn Health
Neurology & pain (2 active studies)
- MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion · Kuros Biosurgery AG
- Testing the Pain Clinical Practice Guideline · Phase 2 · University of Maryland, Baltimore
Cardiovascular (1 active study)
- Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS · Phase 3 · DalCor Pharmaceuticals
Eye & vision (1 active study)
- Inherited Retinal Degenerative Disease Registry · Foundation Fighting Blindness
Pediatric (1 active study)
Common conditions studied in Columbia
- Breast Cancer (8 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Carcinoma, Non-Small-Cell Lung (3 active studies). Recruiting Carcinoma, Non-Small-Cell Lung studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Head and Neck Squamous Cell Carcinoma (3 active studies). Recruiting Head and Neck Squamous Cell Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Obesity (3 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Overweight (3 active studies). Recruiting Overweight studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Brain Tumor (2 active studies). Recruiting Brain Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Columbia
- University of Maryland, Baltimore
- NRG Oncology
- Pfizer
- AstraZeneca
- Eli Lilly and Company
Local regulations and guidelines
Clinical trials in Maryland are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Maryland research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Columbia. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Columbia
Hipa.ai aggregates every recruiting study in Columbia from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Columbia?
There are approximately 80 recruiting clinical trials in Columbia, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Columbia pay participants?
Most recruiting trials in Columbia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Columbia?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Columbia?
The most common conditions under active study in Columbia include Breast Cancer (8), Carcinoma, Non-Small-Cell Lung (3), Head and Neck Squamous Cell Carcinoma (3), Obesity (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Columbia?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Columbia?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Columbia?
Recruiting research sites in Columbia include Central Maryland Radiation Oncology in Howard County, Centennial Medical Group, Central Maryland Radiation Oncology, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Columbia right now?
The largest active categories in Columbia are Cancer & tumors (35), Diabetes & metabolic (8), Vaccines (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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