Blood cancer Clinical Trials in Chapel Hill, NC

As of June 2026, 52 paid clinical trials are recruiting for Blood cancer in Chapel Hill, North Carolina. Blood cancer trials investigate CAR-T cell therapies, bispecific antibodies, BTK and BCL-2 inhibitors, and novel combinations across leukemias, lymphomas, myeloma, and myelodysplastic syndromes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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52 clinical trials for Blood cancer

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Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

for Mantle Cell Lymphoma

1 location in Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT04223765·Phase 1·Recruiting

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for Solid Tumors

65 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT03486873·Phase 3·Recruiting

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Registry for Adults With Plasma Cell Disorders (PCD's)

for Multiple Myeloma

1 location in Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT03717844·Recruiting

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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

67 locations incl. Birmingham

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting

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TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for Lymphoma, Non-Hodgkin

174 locations incl. Birmingham

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 12+

Code: NCT02693535·Phase 2·Recruiting

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

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Collection and Storage of Tissue and Blood Samples From Patients With Cancer

for Hematopoietic and Lymphatic System Neoplasm

140 locations incl. Birmingham

Sponsor: National Cancer Institute LAO

Sex: All·Age: 2 Months+

Code: NCT02474160·Recruiting

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

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Registry of Older Patients With Cancer

for Chronic Myeloproliferative Disorders

7 locations incl. Boone

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 65+

Code: NCT01137825·Recruiting

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Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

for Chronic Myeloproliferative Disorders

1 location in Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18 - 120

Code: NCT01137643·Recruiting

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Conditions in Blood cancer (Chapel Hill, NC)

Multiple myeloma· 17 Acute myeloid leukemia (AML)· 11 Leukemia (other)· 10 Non-Hodgkin lymphoma· 10 Chronic lymphocytic leukemia (CLL)· 8 Hematologic malignancy· 8 Myelodysplastic syndromes (MDS)· 7 Small lymphocytic lymphoma· 7 Follicular lymphoma· 4 Mantle cell lymphoma· 4 Acute lymphoblastic leukemia· 3 Myelofibrosis· 3 Marginal zone lymphoma· 3 Myeloproliferative neoplasm· 2 Hodgkin lymphoma· 2 Diffuse large B-cell lymphoma (DLBCL)· 1 Burkitt lymphoma· 1