Paid Clinical Trials in California

California has 6,497 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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6,497 clinical trials

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A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

for Advanced or Metastatic Solid Tumors

15 locations incl. Santa Monica

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07205718·Phase 1, Phase 2·Recruiting

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A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity

for Obesity

2 locations incl. Anaheim

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT07291232·Phase 1·Recruiting

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A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

for Colorectal Cancer

Drug: Bevacizumab

11 locations incl. Phoenix

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT06948448·Phase 2·Recruiting

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[68Ga]Ga DOTA-5G as a Diagnostic Imaging Agent for Metastatic/Advanced Invasive Lobular Breast Cancer (LBC)

for Metastatic Lobular Breast Carcinoma

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18 - 89

Code: NCT07020806·Phase 1·Recruiting

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Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

for HER2 Expressing Solid Tumors

6 locations incl. Los Angeles

Sponsor: Vironexis Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT07192432·Phase 1, Phase 2·Recruiting

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Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

for Metastatic Colorectal Cancer (CRC)

Drug: Bevacizumab

58 locations incl. Goodyear

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT07228832·Phase 3·Recruiting

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A Research Study Looking at How Food Intake Affects Inno8 in the Body of Healthy People

for Haemophilia A

1 location in Cypress

Sponsor: Novo Nordisk A/S

Sex: Male·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07238816·Phase 1·Recruiting

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Driver Simulator Training to Improve Driving After Stroke

for Stroke

1 location in Sacramento

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 80

Code: NCT06672107·Recruiting

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Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

for Advanced Hepatocellular Carcinoma

Drug: Cabozantinib

4 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06811116·Phase 1, Phase 2·Recruiting

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A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

for Non Small Cell Lung Cancer

11 locations incl. San Francisco

Sponsor: Rondo Therapeutics

Sex: All·Age: 18+

Code: NCT07218003·Phase 1·Enrolling By Invitation

This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment

for Atopic Dermatitis

43 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT07290803·Recruiting

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Dance Mental Health App

for Ankle Injury

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 13 - 18

Code: NCT07219095·Recruiting

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Health Properties of Pecan Nut Consumption

for Healthy Adults

1 location in Davis

Sponsor: University of California, Davis

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT07227259·Recruiting

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Living Well Program: Impact on Healthcare Costs and Clinical Outcomes in Breast Cancer Care

for Anxiety

1 location in Los Angeles

Sponsor: Scott A. Irwin, MD, PhD

Sex: Female·Age: 18+

Code: NCT07236437·Not Yet Recruiting

Testing a Novel Attention Based Training Prevention Strategy for First Responders: FirstFocus a Mobile App

for Wellbeing

1 location in Palo Alto

Sponsor: Palo Alto University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07247149·Enrolling By Invitation

Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention

for Suicidal Thoughts and Behaviors

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 65

Code: NCT06809348·Recruiting

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A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population

for Kidney Disease

6 locations incl. San Diego

Sponsor: Devyser Inc.

Sex: All·Age: 18+

Code: NCT07006831·Recruiting

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Comparing the Efficacy and Safety of the EndoZip System and Apollo ESG in Obese Patients

for Obesity

2 locations incl. Los Angeles

Sponsor: Nitinotes Surgical Ltd.

Sex: All·Age: 21 - 65

Code: NCT07090005·Recruiting

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Phase 3, Open Label Extension Study of ACP-204 in Lewy Body Dementia Psychosis

for Lewy Body Dementia Psychosis

13 locations incl. Irvine

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 55 - 84

Code: NCT07095465·Phase 3·Enrolling By Invitation

A Study to Assess Anktiva in Patients With Long Covid-19.

for Long COVID

1 location in San Francisco

Sponsor: ImmunityBio, Inc.

Sex: All·Age: 18 - 70

Code: NCT07108036·Phase 2·Recruiting

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Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness

for Tobacco Cessation

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07148232·Phase 4·Recruiting

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Comparing a New PSMA Imaging Agent to MRI for Detecting Prostate Cancer, BEACON Trial

for Prostate Carcinoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: Male·Age: 18 - 90

Code: NCT07164027·EARLY_Phase 1·Recruiting

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Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.

for Esophageal Cancer

14 locations incl. Cerritos

Sponsor: SOFIE

Sex: All·Age: 18+

Code: NCT07217704·Phase 3·Recruiting

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ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

for Major Depressive Disorder (MDD)

21 locations incl. Birmingham

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07284667·Phase 2·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

for Ovarian Cancer

23 locations incl. La Jolla

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT07059845·Phase 2·Recruiting

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A Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS)

for Multiple Sclerosis

9 locations incl. Carlsbad

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18 - 65

Code: NCT07074886·Phase 2·Recruiting

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Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures

for Rib Fractures

1 location in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT07145346·Phase 4·Enrolling By Invitation

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

for Bladder Cancer

10 locations incl. Los Angeles

Sponsor: EvolveImmune United, Inc

Sex: All·Age: 18+

Code: NCT07217171·Phase 1·Recruiting

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A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Psoriatic Arthritis

for Arthritis, Psoriatic

16 locations incl. Avondale

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 18+

Code: NCT07223138·Phase 3·Enrolling By Invitation

A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.

for Hidradenitis Suppurativa

Drug: Ritlecitinib

32 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 18 - 75

Code: NCT07228390·Phase 2·Recruiting

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A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors

for Advance Solid Tumors

1 location in Santa Monica

Sponsor: Kivu Bioscience Inc.

Sex: All·Age: 18+

Code: NCT07229313·Phase 1·Recruiting

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A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

42 locations incl. Mobile

Sponsor: Incyte Corporation

Sex: Female·Age: 18 - 99

Code: NCT07023627·Phase 2·Recruiting

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A Study of Efgartigimod in Patients With IgG4-Related Disease

for IgG4-related Disease

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18 - 90

Code: NCT07025330·Phase 2·Recruiting

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Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

for B-cell Acute Lymphoblastic Leukemia (B-ALL)

6 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07109219·Phase 1, Phase 2·Recruiting

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Actinium Therapy for Late-stage Aggressive Sarcomas

for Advanced Soft Tissue Sarcoma

5 locations incl. Los Angeles

Sponsor: Ratio Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07156565·Phase 1·Recruiting

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A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for Alzheimers Disease

Drug: Trontinemab

33 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07170150·Phase 3·Recruiting

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Gen 2 Battrode Wear Study

for Adhesive Wear Time

1 location in Lake Forest

Sponsor: Baxter Healthcare Corporation

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07256951·Recruiting

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A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

for Phelan-McDermid Syndrome

9 locations incl. Glendale

Sponsor: Neuren Pharmaceuticals Limited

Sex: All·Age: 3 - 12

Code: NCT07281079·Phase 3·Recruiting

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A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

for Hyperlipidemia

35 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 64

Code: NCT07216482·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis (SPMS)

Drug: Remibrutinib

30 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07225504·Phase 3·Recruiting

Apply to this trial