Paid Clinical Trials in Burlington, VT
As of June 2026, 167 paid clinical trials are recruiting in Burlington, Vermont. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Burlington offers studies at sites including University of Vermont Medical Center for conditions such as Heart Failure, Acute Myeloid Leukemia, Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Burlington
Trials by drug in Burlington
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167 clinical trials
↓ Download CSVPDAC Regression and Intraoperative Surgical Margin With Neoadjuvant TAMP (PRISM-TAMP)
Bempedoic Acid Therapy for Polycystic Kidney Disease
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
RE-FIT (Remote Exercise for Physical Function in WTC Responders With Prostate Cancer)
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
Evaluation of Protein Loading on Measurement of Renal Reserve
A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine
A Multi-Site Hybrid Type I Effectiveness-Implementation Randomized Trial of an Emergency Care Action Plan for Infants With Medical Complexity
Prolonged Exposure Therapy to Treat Posttraumatic Stress Disorder in Pregnant Patients
SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy.
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Fezolinetant for Treating Hot Flashes in Men With Prostate Cancer
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)
Food Insecurity and Eating Behavior Among Adults Receiving Buprenorphine or Methadone Maintenance Treatment: Pilot Study 2
DOAC - Dosing Options in AntiCoagulation Prophylaxis
Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma
Implementing VTE Prevention in Ambulatory Cancer Care
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Nutritional Prehabilitation to Improve Cancer Outcomes (N-PICO)
Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department
A Phase 1B Investigator Initiated Study of Safety and Tolerability of Dexamethasone (D) in Combination With Venetoclax-based Low-Intensity Therapy (LIT) in Treatment-Naïve Acute Myeloid Leukemia (AML): DLIT-AML
A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations
PumaRx Registry Trial
GyroGlove Use in Essential Tremor Patients
Phase 2/3 Study of KPL-387 in Recurrent Pericarditis
ELEVATE-HFpEF Clinical Study
Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes
A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
Avoiding Radiation Therapy Due to Intracranial Response to Chemotherapy, Targeted Therapy and/or Immuno-ONcology Therapy for Brain Metastases: Pilot Pragmatic Trial
MOHs Surgery and Short-Course Radiation Therapy With Structured Follow-Up for Head & Neck Squamous Cell Skin Cancer
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula
About research studies in Burlington
Burlington has approximately 167 recruiting research studies across a wide range of therapeutic areas. Vermont hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Burlington
Researchers run research studies in Burlington, VT at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Vermont Medical Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer | 80 |
| University of Vermont and State Agricultural College | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | 49 |
| University of Vermont | Heart Failure, AML, AML With Mutated NPM1 | 28 |
| The University of Vermont Medical Center | Atrial Fibrillation, Brain Neoplasms, Adult, Malignant, Brain Tumor | 9 |
| The University of Vermont Medical Center Inc. | Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 6 |
| University of Vermont Cancer Center | Cancer, Diabetes, Leukemia, Myeloid, Acute | 3 |
| UVM MC | Focal Epilepsy | 2 |
| Burlington, VT Investigative | Acute Heart Failure, Heart Failure | 1 |
| Clinical Research Center, University of Vermont Medical Center | Healthy, Healthy Adult, Healthy Male and Female Subjects | 1 |
| Clinical Trial Site | Generalized Myasthenia Gravis | 1 |
| Department of Orthopaedics & Rehabilitation The Larner College of Medicine at The University of Vermont | Shoulder Arthritis, Shoulder Disease, Shoulder Fractures | 1 |
| Fletcher Allen Health Care, University of Vermont Medical School | Glomerular Filtration Rate | 1 |
| Golisano Children's Hospital at University of Vermont Health | Acute Kidney Injury, Chronic Kidney Disease(CKD), Epidemiology | 1 |
| Investigational | Pericarditis, Pericarditis Acute, Recurrent Pericarditis | 1 |
| Local | Recurrent Pericarditis | 1 |
| Ohio State University-Telemedicine | Advanced Pancreatic Carcinoma, Metastatic Pancreatic Carcinoma, Stage II Pancreatic Cancer AJCC v8 | 1 |
| The University of Vermont Children's Hospital | Failed or Difficult Intubation, Sequela, Intubation Complication, Intubation; Difficult | 1 |
| The University of Vermont Larner College of Medicine | Traumatic Injury | 1 |
| The University of Vermont Medical Center, Inc | COPD | 1 |
| UVM Larner College of Medicine MMG/VCT | Clostridioides Difficile Associated Disease | 1 |
| UVM Medical Center - 1 South Prospect Street | Autosomal Dominant Polycystic Kidney Disease (ADPKD) | 1 |
| University of Vemont | Opioid Use Disorder, Posttraumatic Stress Disorder | 1 |
| University of Vermont Children's Hospital | AVB - Atrioventricular Block, Fetal AVB | 1 |
| University of Vermont Med Ctr | Heart Failure | 1 |
| University of Vermont Medical Centre | Essential Tremor | 1 |
Active & Upcoming Studies in Burlington (2026)
Recruiting trials in Burlington grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (72 active studies)
- Gut Microbiome Changes During Abemaciclib Therapy in Breast Cancer · University of Vermont Medical Center
- PDAC Regression and Intraoperative Surgical Margin With Neoadjuvant TAMP (PRISM-TAMP) · Phase 1, Phase 2 · University of Vermont
Cardiovascular (17 active studies)
- ELEVATE-HFpEF Clinical Study · Medtronic Cardiac Rhythm and Heart Failure
- Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin · Phase 3 · AstraZeneca
Neurology & pain (7 active studies)
- SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy. · Phase 2 · University of Rochester
- Long-term Safety and Tolerability of BHV-7000 · Phase 2 · Biohaven Therapeutics Ltd.
Pediatric (4 active studies)
- Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome · HELP for NOWS Consortium
- Emergency Care Action Plans for Infants with Medical Complexity · University of Vermont
Mental health & behavior (2 active studies)
- Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes · Phase 2 · University of Vermont
- Remote Smoking Cessation in Hospitalized Cardiac Patients · University of Vermont Medical Center
Vaccines (1 active study)
Diabetes & metabolic (1 active study)
- Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes · UNC Lineberger Comprehensive Cancer Center
Eye & vision (1 active study)
Common conditions studied in Burlington
- Heart Failure (7 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Acute Myeloid Leukemia (6 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Breast Cancer (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Cancer (3 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Carcinoma, Non-Small-Cell Lung (3 active studies). Recruiting Carcinoma, Non-Small-Cell Lung studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Burlington
- University of Vermont
- National Cancer Institute (NCI)
- University of Vermont Medical Center
- Children's Oncology Group
- NRG Oncology
Local regulations and guidelines
Clinical trials in Vermont are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Vermont research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Burlington. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Burlington
Hipa.ai aggregates every recruiting study in Burlington from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Burlington?
There are approximately 167 recruiting clinical trials in Burlington, Vermont listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Burlington pay participants?
Most recruiting trials in Burlington compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Burlington?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Burlington?
The most common conditions under active study in Burlington include Heart Failure (7), Acute Myeloid Leukemia (6), Breast Cancer (4), Anatomic Stage II Breast Cancer AJCC v8 (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Burlington?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Burlington on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Burlington?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Burlington?
Recruiting research sites in Burlington include University of Vermont Medical Center, University of Vermont and State Agricultural College, University of Vermont, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Burlington right now?
The largest active categories in Burlington are Cancer & tumors (72), Cardiovascular (17), Neurology & pain (7). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.