Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department

Part of paid clinical trials in Burlington, Vermont.

Sponsor
University of Vermont
Study ID
NCT07129902
Status
Recruiting
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Conditions

  • Opioid Use Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Contingency Management — BEHAVIORAL
    Participants in the active arm will receive payment (monetary incentive) contingent on outpatient MOUD treatment attendance.
  • Usual care as prescribed by the ED physicians — BEHAVIORAL
    All participants will receive standard outpatient care at their clinic.

Study Details

Project Summary The goal of this pilot clinical trial is to assess contingency management (CM) for increasing attendance at outpatient clinics after Medication for Opioid Use Disorder (MOUD) prescription and clinic referral occurred in the hospital Emergency Department (ED). * The researchers will compare usual care (UC)+CM to UC alone to see if 1) CM works to promote MOUD clinic attendance after discharge from the ED and 2) demonstrate feasibility of providing CM in the ED and outpatient MOUD clinic settings. * Researchers will randomize 30 adults who started MOUD in the ED into two conditions. These conditions consist of (A) UC alone: A referral to an outpatient buprenorphine or methadone provider with reminders from STAR program staff or (B) UC+CM: UC plus financial incentives dependent on MOUD clinic attendance to receive an MOUD prescription. The primary outcome of interest is the number of participants who receive their first MOUD prescription from the outpatient clinic after discharge from the ED in UC+CM compared to the UC-only condition. A secondary outcome will be the proportion of participants who kept attending outpatient MOUD treatment by the end of the 30-day study period between UC+CM and UC conditions. An exploratory outcome will be biochemically-verified illicit opioid abstinence measured at day 30.

Key Dates

Start date
Sep 2, 2025
Status verified
May 2026
Primary completion
Apr 30, 2027
Completion
May 31, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Contingency Management
    Participants assigned to this arm will receive incentives when they complete their first outpatient MOUD clinic visit and when they complete subsequent visits to pick up their MOUD prescription for the 30-day study period.
  • Active Comparator: Usual Care
    All participants will receive standard outpatient care at their clinic.

Primary Outcome Measure

Intake at outpatient MOUD clinic [ Time Frame: 30 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Vermont Medical CenterBurlingtonVermont05405
Eric Thrailkill, Ph.D.
[email protected]
602-291-7311
Eric Thrailkill, Ph.D. (PRINCIPAL_INVESTIGATOR)

Find similar trials in Burlington, VT

By research site
University of Vermont Medical Center· Burlington, VT

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