Blood cancer Clinical Trials in Bethesda, MD

As of June 2026, 73 paid clinical trials are recruiting for Blood cancer in Bethesda, Maryland. Blood cancer trials investigate CAR-T cell therapies, bispecific antibodies, BTK and BCL-2 inhibitors, and novel combinations across leukemias, lymphomas, myeloma, and myelodysplastic syndromes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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73 clinical trials for Blood cancer

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A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Drug: Daratumumab

67 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05552222·Phase 3·Recruiting

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Vaccine Responses in Patients With B Cell Malignancies

for Lymphoma

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 90

Code: NCT05170399·Phase 4·Recruiting

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

746 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting

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Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult MDS

for Myelodysplastic Syndromes

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 Day - 120·Accepts healthy volunteers

Code: NCT05350748·Recruiting

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A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

for Chronic Lymphocytic Leukemia

Drug: Ibrutinib

19 locations incl. Anaheim

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05254743·Phase 3·Recruiting

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

164 locations incl. Birmingham

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting

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A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

for Relapsed/Refractory Follicular Lymphoma

Drug: Rituximab

49 locations incl. Fresno

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05100862·Phase 3·Recruiting

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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

for B-cell Malignancy

31 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05006716·Phase 1, Phase 2·Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

621 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

for Haematological Malignancy

6 locations incl. Atlanta

Sponsor: CellCentric Ltd.

Sex: All·Age: 18+

Code: NCT04068597·Phase 1, Phase 2·Recruiting

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Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

for Non-Hodgkin's Lymphoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04002947·Phase 2·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

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Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 85

Code: NCT03986034·Phase 2·Recruiting

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Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

for Endocrine Tumors

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 72

Code: NCT03412877·Phase 2·Recruiting

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Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

for Epstein-Barr Virus Infections

Drug: Nivolumab

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT03258567·Phase 2·Recruiting

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Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

for Lymphoma

Drug: Venetoclax

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT03223610·Phase 1, Phase 2·Recruiting

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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

67 locations incl. Birmingham

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting

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Sample Collection and Tracking for the Developmental Therapeutics Clinic

for Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT03269578·Recruiting

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Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

for Leukemia

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 3 - 65

Code: NCT03226704·Enrolling By Invitation

Clonal Evolution in Follicular Lymphoma

for Follicular Lymphoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03190928·Recruiting

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A Phase 1 Study of Ruxolitinib, Steroids and Lenalidomide for Relapsed/Refractory Multiple Myeloma (RRMM) Patients

for Multiple Myeloma

Drug: Ruxolitinib

13 locations incl. Alhambra

Sponsor: Oncotherapeutics

Sex: All·Age: 18+

Code: NCT03110822·Phase 1·Recruiting

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Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

for Multiple Myeloma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT02682667·Recruiting

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

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Gene Therapy Follow-up Protocol for People Previously Enrolled in CAR-T Cell Studies

for Lyphoma, B-Cell

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT02473757·Enrolling By Invitation

Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials

for Pediatric Cancers

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 99

Code: NCT02315599·Enrolling By Invitation

Tissue Collection for Studies of Lymph Cancer

for Hodgkin Disease

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT01676805·Recruiting

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Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

for Prostate Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 3+

Code: NCT01441089·Recruiting

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

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Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

for Waldenstrom Macroglobulinemia

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 110

Code: NCT00923507·Recruiting

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Collection of Tissue Samples for Cancer Research

for Neoplasms

16 locations incl. Sacramento

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 Months+

Code: NCT00900198·Recruiting

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Biology Studies of Hematologic Cancers

for Acute Lymphoblastic Leukemia

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 120

Code: NCT00923442·Enrolling By Invitation

Conditions in Blood cancer (Bethesda, MD)

Non-Hodgkin lymphoma· 20 Hematologic malignancy· 14 Multiple myeloma· 12 Acute myeloid leukemia (AML)· 10 Myelodysplastic syndromes (MDS)· 10 Acute lymphoblastic leukemia· 9 Leukemia (other)· 9 Chronic lymphocytic leukemia (CLL)· 8 Diffuse large B-cell lymphoma (DLBCL)· 7 Small lymphocytic lymphoma· 6 Follicular lymphoma· 3 Mantle cell lymphoma· 3 Marginal zone lymphoma· 3 Myelofibrosis· 2 Myeloproliferative neoplasm· 2 Hodgkin lymphoma· 2 Burkitt lymphoma· 2