Behavioral health Clinical Trials in Baltimore, MD

As of June 2026, 81 paid clinical trials are recruiting for Behavioral health in Baltimore, Maryland. Behavioral health trials span mental-health pharmacotherapy and addiction treatment — testing new agents and therapies for depression, anxiety, opioid use disorder, alcohol use, and tobacco cessation. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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81 clinical trials for Behavioral health

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The Collaborative Care PrTNER Study

for HIV

2 locations incl. Baltimore

Sponsor: Children's Hospital of Philadelphia

Sex: Male·Age: 15 - 29·Accepts healthy volunteers

Code: NCT06585631·Recruiting

Apply to this trial

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

for Treatment Resistant Depression

34 locations incl. Tucson

Sponsor: atai Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06524830·Phase 2·Recruiting

Apply to this trial

Older Adults, Methadone, and Cognitive Function

for Opioid Use Disorder

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 55+

Code: NCT07153029·Recruiting

Apply to this trial

EXPANDED SCOPE for Parent Grant Entitled, "Peer Recovery Support Services for Individuals in Recovery Residences on MOUD"

for Opioid Use Disorder

1 location in Baltimore

Sponsor: Potomac Health Foundations

Sex: All·Age: 18+

Code: NCT06696157·Recruiting

Apply to this trial

Psilocybin-assisted Treatment for Cannabis Use Disorder

for Cannabis Use Disorder

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06660381·Phase 1·Recruiting

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Continuum of Care in Hospitalized Patients With Opioid/Stimulant Use Disorder and Infectious Complications From Drug Use

for Opioid Use Disorder

4 locations incl. Washington D.C.

Sponsor: Elana Rosenthal

Sex: All·Age: 18+

Code: NCT06513156·Recruiting

Apply to this trial

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

for Substance Use Disorder

1 location in Baltimore

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT06552741·Recruiting

Apply to this trial

The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles

for Cannabis Use

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 55·Accepts healthy volunteers

Code: NCT05602649·Phase 1·Recruiting

Apply to this trial

Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

for Respiratory Failure

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06341972·Recruiting

Apply to this trial

Opioid Use After Laparoscopic Salpingectomy

for Opioid Use

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06434233·Phase 4·Recruiting

Apply to this trial

Psilocybin in Chronic Low Back Pain and Depression

for Chronic Low-back Pain

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 80

Code: NCT06355414·Phase 1·Recruiting

Apply to this trial

Using Personalized Assessments in the Treatment of Childhood OCD

for Obsessive-Compulsive Disorder

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 8 - 17

Code: NCT06407648·Recruiting

Apply to this trial

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

for Opioid Use Disorder

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 70

Code: NCT06067737·Phase 2·Recruiting

Apply to this trial

Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl

for Opioid Use Disorder

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06089707·Phase 3·Recruiting

Apply to this trial

DINO RCT - Treating Anxiety in Children With Autism

for Autism Spectrum Disorder

1 location in Baltimore

Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Sex: All·Age: 4 - 6·Accepts healthy volunteers

Code: NCT06066983·Recruiting

Apply to this trial

Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal

for Opiate Withdrawal Syndrome

2 locations incl. Baltimore

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05995535·Phase 2·Recruiting

Apply to this trial

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

for Tobacco Use Disorder

3 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT05452772·Phase 2·Recruiting

Apply to this trial

Semaglutide Therapy for Alcohol Reduction (STAR)

for Addiction

Drug: Semaglutide

1 location in Baltimore

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 18 - 110

Code: NCT06015893·Phase 2·Recruiting

Apply to this trial

Cerebellar Involvement in Alcohol Use Disorder (AUD)

for Alcohol Use Disorder

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 55·Accepts healthy volunteers

Code: NCT05732207·Recruiting

Apply to this trial

Impact of Exercise Groups on Patient Mental Health and Wellbeing in an Acute Psychiatric Inpatient Unit

for Psychiatric Hospitalization

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05859204·Enrolling By Invitation

Spironolactone in Alcohol Use Disorder (SAUD)

for Alcohol Use Disorder

1 location in Baltimore

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 21 - 99

Code: NCT05807139·Phase 1·Recruiting

Apply to this trial

Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention

for Polysubstance Addiction

4 locations incl. Washington D.C.

Sponsor: University of Maryland, College Park

Sex: All·Age: 18+

Code: NCT05973838·Recruiting

Apply to this trial

Alcohol Research in HIV: Relapse Prevention

for HIV

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05163301·Recruiting

Apply to this trial

Evaluating Buspirone to Treat Opioid Withdrawal

for Opioid Use Disorder

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 75

Code: NCT05511909·Phase 2·Recruiting

Apply to this trial

Divided or Single Exposure (DOSE) Study

for Opioid Use Disorder

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 100

Code: NCT05459402·Phase 2, Phase 3·Recruiting

Apply to this trial

Orexin s Role in the Neurobiology of Substance Use Disorder

for Nicotine Dependence

1 location in Baltimore

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT05630781·Recruiting

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Defining Neurobiological Links Between Substance Use and Mental Illness

for Major Depressive Disorder

1 location in Baltimore

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT05538910·Recruiting

Apply to this trial

Targeting Emotion Dysregulation to Reduce Suicide in People With Psychosis

for Psychosis

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05440214·Recruiting

Apply to this trial

Oral Cannabidiol for Tobacco Cessation

for Tobacco Use

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05445804·Phase 1·Recruiting

Apply to this trial

Suvorexant as an Adjunct to Buprenorphine in Persons Who Use Fentanyl

for Suvorexant

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 65

Code: NCT05145764·Phase 2·Recruiting

Apply to this trial

Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial

for Schizophrenia

7 locations incl. Los Angeles

Sponsor: New York State Psychiatric Institute

Sex: All·Age: 18 - 65

Code: NCT05208190·Phase 4·Recruiting

Apply to this trial

Developing a Clinical Outcome Assessment for Opioid Craving

for Opioid Craving

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05109429·Recruiting

Apply to this trial

Glucose Variability and Cognition in Prediabetes

for Glucose Metabolism Disorders (Including Diabetes Mellitus)

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT04201600·Recruiting

Apply to this trial

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

for Opioid Withdrawal

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 65

Code: NCT05027919·Phase 2·Recruiting

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A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

for Depression

Drug: Cariprazine

69 locations incl. Bentonville

Sponsor: AbbVie

Sex: All·Age: 10 - 17

Code: NCT04777357·Phase 3·Recruiting

Apply to this trial

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

for Depressive Symptoms

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 85

Code: NCT04123314·EARLY_Phase 1·Recruiting

Apply to this trial

Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH

for Alcohol Use Disorder

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT03845205·Recruiting

Apply to this trial

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

49 locations incl. Phoenix

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting

Apply to this trial

Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disorders (SUDs)

for Opioid-use Disorder

4 locations incl. Tampa

Sponsor: InSightec

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT04197921·Recruiting

Apply to this trial

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for Treatment Resistant Depression

98 locations incl. Birmingham

Sponsor: LivaNova

Sex: All·Age: 18+

Code: NCT03887715·Recruiting

Apply to this trial

Conditions in Behavioral health (Baltimore, MD)

Opioid use disorder· 21 Depression· 15 Alcohol use disorder· 12 Substance use disorder· 9 Tobacco / nicotine use· 9 Cannabis use / cannabis use disorder· 7 Anxiety· 6 Schizophrenia· 4 PTSD (post-traumatic stress disorder)· 3 ADHD· 2 Bipolar disorder· 1 Obsessive-compulsive disorder (OCD)· 1