How many Relugolix clinical trials are there?

53 Relugolix clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 22 are actively recruiting participants. 19 are marked completed.

Are Relugolix clinical trials recruiting in 2026?

Yes — 22 Relugolix trials are actively recruiting in 2026, with 439 U.S. sites across 41 states. See the recruiting trials and the per-state site list further down this page.

What conditions is Relugolix being studied for?

Relugolix is being studied for Prostate Cancer, Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Uterine Fibroids, Heavy Menstrual Bleeding and 54 more. The trials are grouped by indication on this page.

What phase is Relugolix in?

Relugolix clinical trials span 1 Phase 4, 20 Phase 3, 18 Phase 2, 6 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.

Who sponsors Relugolix clinical trials?

The lead sponsor across the most Relugolix trials is Myovant Sciences GmbH, with 33 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Relugolix Clinical Trials (2026): 53 Studies for Prostate Cancer & Prostate Adenocarcinoma

Creator: Hipa.ai Research
Published: 2026-05-08T19:26:29.324Z

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: June 12, 2026.

53 Relugolix clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 25 indications (including Prostate Cancer & Prostate Adenocarcinoma) and 19,547 total planned enrollment. 20 Phase 3 Relugolix trials and 18 Phase 2, 1 Phase 4 are listed. 23 Relugolix clinical trials are actively recruiting at 439 U.S. sites across 41 states. Most recent activity: NCT04513717 (Dec 2033).

Where to Participate: All Relugolix Trial Sites in the U.S. (439 sites across 41 states)

Every actively recruiting Relugolixtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

State	Facility	City	Trial	Map
AL	Mobile	Mobile36604	NCT05862272	Map
AK	Alaska Breast Care and Surgery LLC	Anchorage99508	NCT04423211	Map
AK	Alaska Oncology and Hematology LLC	Anchorage99508	NCT04423211	Map
AK	Alaska Women's Cancer Care	Anchorage99508	NCT04423211	Map
AK	Anchorage Associates in Radiation Medicine	Anchorage98508	NCT04423211	Map
AK	Katmai Oncology Group	Anchorage99508	NCT04423211	Map
AK	Providence Alaska Medical Center	Anchorage99508	NCT04423211	Map
AZ	Chandler	Chandler85224	NCT05862272	Map
AZ	Mesa	Mesa85209	NCT05862272	Map
AZ	Peoria	Peoria85381	NCT05862272	Map
AZ	Cancer Center at Saint Joseph's	Phoenix85004	NCT04423211	Map
AZ	Mayo Clinic in Arizona	Phoenix85054	NCT06378866	Map
AZ	Phoenix	Phoenix85018	NCT05862272	Map
AZ	Mayo Clinic in Arizona	Scottsdale85259	NCT07025369	Map
AZ	Tucson	Tucson85715-3834	NCT05862272	Map
AR	Mercy Hospital Fort Smith	Fort Smith72903	NCT04423211	Map
CA	Mission Hope Medical Oncology - Arroyo Grande	Arroyo Grande93420	NCT04423211	Map
CA	Burbank	Burbank91506-1773	NCT05862272	Map
CA	Providence Saint Joseph Medical Center/Disney Family Cancer Center	Burbank91505	NCT04423211	Map
CA	Canoga Park	Canoga Park91303	NCT05862272	Map
CA	Mercy Cancer Center - Carmichael	Carmichael95608	NCT04423211	Map
CA	Mercy San Juan Medical Center	Carmichael95608	NCT04423211	Map
CA	City of Hope Corona	Corona92882	NCT04423211	Map
CA	City of Hope Comprehensive Cancer Center	Duarte91010	NCT04423211	Map
CA	Mercy Cancer Center - Elk Grove	Elk Grove95758	NCT04423211	Map
CA	Encinitas	Encinitas92024-1329	NCT05862272	Map
CA	UC San Diego Health System - Encinitas	Encinitas92024	NCT04423211	Map
CA	Inglewood	Inglewood90301	NCT05862272	Map
CA	UC San Diego Moores Cancer Center	La Jolla92093	NCT04423211	Map
CA	City of Hope Antelope Valley	Lancaster93534	NCT04423211	Map
CA	Lomita	Lomita90717-2101	NCT05862272	Map
CA	Long Beach	Long Beach90805-4587	NCT05862272	Map
CA	VA Long Beach Healthcare System, Long Beach, CA	Long Beach90822	NCT04787744	Map
CA	Los Angeles	Los Angeles90036	NCT05862272	Map
CA	UCLA / Jonsson Comprehensive Cancer Center	Los Angeles90095	NCT04423211	Map
CA	Mercy Cancer Center - Rocklin	Rocklin95765	NCT04423211	Map
CA	Mercy Cancer Center - Sacramento	Sacramento95816	NCT04423211	Map
CA	Sacramento	Sacramento95817-2307	NCT05862272	Map
CA	UC San Diego Medical Center - Hillcrest	San Diego92103	NCT04423211	Map
CA	San Fernando	San Fernando91340-4199	NCT05862272	Map
CA	Pacific Central Coast Health Center-San Luis Obispo	San Luis Obispo93401	NCT04423211	Map
CA	Mission Hope Medical Oncology - Santa Maria	Santa Maria93444	NCT04423211	Map
CA	City of Hope South Pasadena	South Pasadena91030	NCT04423211	Map
CA	Stanford	Stanford94305-2200	NCT05862272	Map
CA	Saint Joseph's Medical Center	Stockton95204	NCT04423211	Map
CA	City of Hope Upland	Upland91786	NCT04423211	Map
CA	Valley Village	Valley Village91607	NCT05862272	Map
CA	VA Greater Los Angeles Healthcare System, West Los Angeles, CA	West Los Angeles90073	NCT04787744	Map
CA	Woodland Memorial Hospital	Woodland95695	NCT04423211	Map
CO	Aurora	Aurora80045-2517	NCT05862272	Map
CO	Penrose-Saint Francis Healthcare	Colorado Springs80907	NCT04423211	Map
CO	Rocky Mountain Cancer Centers-Penrose	Colorado Springs80907	NCT04423211	Map
CO	Saint Francis Cancer Center	Colorado Springs80923	NCT04423211	Map
CO	Dillon Health Center/Shaw Cancer Center	Dillon80435	NCT04423211	Map
CO	Shaw Cancer Center	Edwards81632	NCT04423211	Map
CO	Greenwood Village	Greenwood Village80111	NCT05862272	Map
CO	Lakewood	Lakewood80228	NCT05862272	Map
CO	Saint Anthony Hospital	Lakewood80228	NCT04423211	Map
CO	Longmont United Hospital	Longmont80501	NCT04423211	Map
CO	Saint Mary Corwin Medical Center	Pueblo81004	NCT04423211	Map
CO	Saint Anthony North Hospital	Westminster80023	NCT04423211	Map
CT	Yale Cancer Center	New Haven06520	NCT06111781	Map
DC	Sibley Memorial Hospital	Washington D.C.20016	NCT04423211	Map
DC	Washington	Washington D.C.02011	NCT05862272	Map
DC	Washington DC VA Medical Center, Washington, DC	Washington D.C.20422-0001	NCT04787744	Map
FL	Aventura	Aventura33180	NCT05862272	Map
FL	Bay Pines VA Healthcare System, Pay Pines, FL	Bay Pines33744	NCT04787744	Map
FL	Deland	DeLand32720	NCT05862272	Map
FL	Hialeah	Hialeah33016	NCT05862272	Map
FL	Mayo Clinic in Florida	Jacksonville32224-9980	NCT06378866	Map
FL	Kissimmee	Kissimmee34741-2358	NCT05862272	Map
FL	Lake Worth	Lake Worth33461	NCT05862272	Map
FL	Margate	Margate33063-5715	NCT05862272	Map
FL	Miami	Miami33126	NCT05862272	Map
FL	Miami	Miami33155	NCT05862272	Map
FL	Miami	Miami33173	NCT05862272	Map
FL	Miami Cancer Institute at Baptist Health, Inc.	Miami33176	NCT07455903	Map
FL	University of Miami	Miami33136	NCT06111313	Map
FL	Miami Beach	Miami Beach33140	NCT05862272	Map
FL	Miami Springs	Miami Springs33166	NCT05862272	Map
FL	New Port Richey	New Port Richey34652-4020	NCT05862272	Map
FL	New Port Richey	New Port Richey34652	NCT05862272	Map
FL	AdventHealth Orlando	Orlando32803	NCT06631521	Map
FL	Orlando	Orlando32808	NCT05862272	Map
FL	Orlando	Orlando32819	NCT05862272	Map
FL	Panama City	Panama City32405	NCT05862272	Map
FL	Sarasota	Sarasota34239	NCT05862272	Map
FL	Tamarac	Tamarac33321	NCT05862272	Map
FL	Moffitt Cancer Center	Tampa33612	NCT04423211	Map
FL	Moffitt Cancer Center - McKinley Campus	Tampa33612	NCT04423211	Map
FL	Moffitt Cancer Center-International Plaza	Tampa33607	NCT04423211	Map
FL	Tampa	Tampa33614-1874	NCT05862272	Map
FL	Venice	Venice34285	NCT05862272	Map
FL	Moffitt Cancer Center at Wesley Chapel	Wesley Chapel33544	NCT04423211	Map
FL	West Palm Beach	West Palm Beach33409	NCT05862272	Map
GA	Atlanta	Atlanta30342	NCT05862272	Map
GA	Atlanta	Atlanta30363	NCT05862272	Map
GA	Emory Proton Therapy Center	Atlanta30308	NCT06650579	Map
GA	Emory Saint Joseph's Hospital	Atlanta30342	NCT06650579	Map
GA	Emory University Hospital/Winship Cancer Institute	Atlanta30322	NCT06650579	Map
GA	Winship at Emory Midtown	Atlanta30308	NCT06650579	Map
GA	College Park	College Park30349-3103	NCT05862272	Map
GA	Fayetteville	Fayetteville31204	NCT05862272	Map
GA	Norcross	Norcross30093	NCT05862272	Map
ID	Saint Luke's Cancer Institute - Boise	Boise83712	NCT04423211	Map
ID	Kootenai Health - Coeur d'Alene	Coeur d'Alene83814	NCT04423211	Map
ID	Saint Luke's Cancer Institute - Fruitland	Fruitland83619	NCT04423211	Map
ID	Idaho Falls	Idaho Falls83404-8322	NCT05862272	Map
ID	Idaho Falls	Idaho Falls83404	NCT05862272	Map
ID	Meridian	Meridian83646	NCT05862272	Map
ID	Saint Luke's Cancer Institute - Meridian	Meridian83642	NCT04423211	Map
ID	Saint Luke's Cancer Institute - Nampa	Nampa83687	NCT04423211	Map
ID	Kootenai Clinic Cancer Services - Post Falls	Post Falls83854	NCT04423211	Map
ID	Saint Luke's Cancer Institute - Twin Falls	Twin Falls83301	NCT04423211	Map
IL	Alton Memorial Hospital	Alton62002	NCT04423211	Map
IL	OSF Saint Anthony's Health Center	Alton62002	NCT04423211	Map
IL	Rush-Copley Medical Center	Aurora60504	NCT04423211	Map
IL	Illinois CancerCare-Bloomington	Bloomington61704	NCT04423211	Map
IL	Illinois CancerCare-Canton	Canton61520	NCT04423211	Map
IL	Memorial Hospital of Carbondale	Carbondale62902	NCT04423211	Map
IL	SIH Cancer Institute	Carterville62918	NCT04423211	Map
IL	Illinois CancerCare-Carthage	Carthage62321	NCT04423211	Map
IL	Centralia Oncology Clinic	Centralia62801	NCT04423211	Map
IL	Chicago	Chicago60607-4911	NCT05862272	Map
IL	Chicago	Chicago60616	NCT05862272	Map
IL	Northwestern University	Chicago60611	NCT04423211	Map
IL	Northwestern University	Chicago60611	NCT06499870	Map
IL	Rush MD Anderson Cancer Center	Chicago60612	NCT04423211	Map
IL	University of Illinois	Chicago60612	NCT04423211	Map
IL	Carle at The Riverfront	Danville61832	NCT04423211	Map
IL	Cancer Care Specialists of Illinois - Decatur	Decatur62526	NCT04423211	Map
IL	Decatur Memorial Hospital	Decatur62526	NCT04423211	Map
IL	Northwestern Medicine Cancer Center Kishwaukee	DeKalb60115	NCT04423211	Map
IL	Carle Physician Group-Effingham	Effingham62401	NCT04423211	Map
IL	Crossroads Cancer Center	Effingham62401	NCT04423211	Map
IL	Illinois CancerCare-Eureka	Eureka61530	NCT04423211	Map
IL	Illinois CancerCare-Galesburg	Galesburg61401	NCT04423211	Map
IL	Northwestern Medicine Cancer Center Delnor	Geneva60134	NCT04423211	Map
IL	Edward Hines Jr. VA Hospital, Hines, IL	Hines60141-3030	NCT04787744	Map
IL	Illinois CancerCare-Kewanee Clinic	Kewanee61443	NCT04423211	Map
IL	Rush MD Anderson Cancer Center at Rush Lisle	Lisle60532	NCT04423211	Map
IL	Illinois CancerCare-Macomb	Macomb61455	NCT04423211	Map
IL	Carle Physician Group-Mattoon/Charleston	Mattoon61938	NCT04423211	Map
IL	SSM Health Good Samaritan	Mount Vernon62864	NCT04423211	Map
IL	Cancer Care Center of O'Fallon	O'Fallon62269	NCT04423211	Map
IL	HSHS Saint Elizabeth's Hospital	O'Fallon62269	NCT04423211	Map
IL	Northwestern Medicine Oak Brook	Oak Brook60523	NCT04423211	Map
IL	Rush MD Anderson Cancer Center at Rush Oak Park	Oak Park60304	NCT04423211	Map
IL	Illinois CancerCare-Ottawa Clinic	Ottawa61350	NCT04423211	Map
IL	Illinois CancerCare-Pekin	Pekin61554	NCT04423211	Map
IL	Illinois CancerCare-Peoria	Peoria61615	NCT04423211	Map
IL	Methodist Medical Center of Illinois	Peoria61636	NCT04423211	Map
IL	Illinois CancerCare-Peru	Peru61354	NCT04423211	Map
IL	Illinois CancerCare-Princeton	Princeton61356	NCT04423211	Map
IL	UW Health Carbone Cancer Center Rockford	Rockford61114	NCT04423211	Map
IL	Schaumburg	Schaumburg60173-5831	NCT05862272	Map
IL	Southern Illinois University School of Medicine	Springfield62702	NCT04423211	Map
IL	Springfield Clinic	Springfield62702	NCT04423211	Map
IL	Springfield Memorial Hospital	Springfield62781	NCT04423211	Map
IL	Carle Cancer Center	Urbana61801	NCT04423211	Map
IL	The Carle Foundation Hospital	Urbana61801	NCT04423211	Map
IL	Northwestern Medicine Cancer Center Warrenville	Warrenville60555	NCT04423211	Map
IL	Illinois CancerCare - Washington	Washington61571	NCT04423211	Map
IN	Richard L. Roudebush VA Medical Center, Indianapolis, IN	Indianapolis46202-2884	NCT04787744	Map
IA	Mercy Hospital	Cedar Rapids52403	NCT04423211	Map
IA	Oncology Associates at Mercy Medical Center	Cedar Rapids52403	NCT04423211	Map
KS	Central Care Cancer Center - Garden City	Garden City67846	NCT04423211	Map
KS	Lenexa	Lenexa66215-2733	NCT05862272	Map
KS	Mercy Hospital Pittsburg	Pittsburg66762	NCT04423211	Map
KS	Wichita	Wichita67211	NCT05862272	Map
KY	Saint Joseph Hospital	Lexington40504	NCT04423211	Map
KY	Saint Joseph Hospital East	Lexington40509	NCT04423211	Map
KY	Saint Joseph Radiation Oncology Resource Center	Lexington40504	NCT04423211	Map
LA	LSU Health Baton Rouge-North Clinic	Baton Rouge70805	NCT04423211	Map
LA	Our Lady of the Lake Physician Group	Baton Rouge70808	NCT04423211	Map
LA	Covington	Covington70433	NCT05862272	Map
LA	Marrero	Marrero70072	NCT05862272	Map
LA	Metairie	Metairie70001	NCT05862272	Map
LA	New Orleans	New Orleans70115-6235	NCT05862272	Map
LA	New Orleans	New Orleans70127	NCT05862272	Map
LA	Slidell	Slidell70458-2004	NCT05862272	Map
MD	Baltimore	Baltimore21205	NCT05862272	Map
MD	Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD	Baltimore21201	NCT04787744	Map
MD	Johns Hopkins University/Sidney Kimmel Cancer Center	Baltimore21287	NCT04423211	Map
MD	Suburban Hospital	Bethesda20814	NCT04423211	Map
MD	Laurel	Laurel20707-5203	NCT05862272	Map
MD	Towson	Towson21204	NCT05862272	Map
MA	Dana-Farber Cancer Institute	Boston02215	NCT05765500	Map
MA	VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA	Boston02130	NCT04787744	Map
MA	Dana-Farber Cancer Institute at Foxborough	Foxborough02035	NCT05765500	Map
MI	University of Michigan	Ann Arbor48109	NCT07100782	Map
MI	VA Ann Arbor Healthcare System, Ann Arbor, MI	Ann Arbor48105	NCT04787744	Map
MI	Bay City	Bay City48706	NCT05862272	Map
MI	Dearborn Heights	Dearborn Heights48127	NCT05862272	Map
MI	Detroit	Detroit48201	NCT05862272	Map
MN	Minnesota Oncology - Burnsville	Burnsville55337	NCT04423211	Map
MN	Minnesota Oncology Hematology PA-Chaska	Chaska55318	NCT04423211	Map
MN	Mercy Hospital	Coon Rapids55433	NCT04423211	Map
MN	Minnesota Oncology - Coon Rapids	Coon Rapids55433	NCT04423211	Map
MN	Fairview Southdale Hospital	Edina55435	NCT04423211	Map
MN	Minnesota Oncology - Edina	Edina55435	NCT04423211	Map
MN	Fairview Clinics and Surgery Center Maple Grove	Maple Grove55369	NCT04423211	Map
MN	Minnesota Oncology - Maple Grove	Maple Grove55369	NCT04423211	Map
MN	Minnesota Oncology Hematology PA-Maplewood	Maplewood55109	NCT04423211	Map
MN	Saint John's Hospital - Healtheast	Maplewood55109	NCT04423211	Map
MN	Abbott-Northwestern Hospital	Minneapolis55407	NCT04423211	Map
MN	Health Partners Inc	Minneapolis55454	NCT04423211	Map
MN	Hennepin County Medical Center	Minneapolis55415	NCT04423211	Map
MN	Monticello Cancer Center	Monticello55362	NCT04423211	Map
MN	North Memorial Medical Health Center	Robbinsdale55422	NCT04423211	Map
MN	Mayo Clinic in Rochester	Rochester55905	NCT06378866	Map
MN	Coborn Cancer Center at Saint Cloud Hospital	Saint Cloud56303	NCT04423211	Map
MN	Park Nicollet Clinic - Saint Louis Park	Saint Louis Park55416	NCT04423211	Map
MN	Regions Hospital	Saint Paul55101	NCT04423211	Map
MN	United Hospital	Saint Paul55102	NCT04423211	Map
MN	Saint Francis Regional Medical Center	Shakopee55379	NCT04423211	Map
MN	Lakeview Hospital	Stillwater55082	NCT04423211	Map
MN	Ridgeview Medical Center	Waconia55387	NCT04423211	Map
MN	Rice Memorial Hospital	Willmar56201	NCT04423211	Map
MN	Minnesota Oncology Hematology PA-Woodbury	Woodbury55125	NCT04423211	Map
MS	Baptist Cancer Center-Grenada	Grenada38901	NCT04423211	Map
MS	Baptist Memorial Hospital and Cancer Center-Union County	New Albany38652	NCT04423211	Map
MS	Baptist Memorial Hospital and Cancer Center-Oxford	Oxford38655	NCT04423211	Map
MS	Ridgeland	Ridgeland39157-5179	NCT05862272	Map
MO	Central Care Cancer Center - Bolivar	Bolivar65613	NCT04423211	Map
MO	Mercy Cancer Center - Cape Girardeau	Cape Girardeau63703	NCT04423211	Map
MO	Saint Francis Medical Center	Cape Girardeau63703	NCT04423211	Map
MO	Siteman Cancer Center at Saint Peters Hospital	City of Saint Peters63376	NCT04423211	Map
MO	Siteman Cancer Center at West County Hospital	Creve Coeur63141	NCT04423211	Map
MO	Parkland Health Center - Farmington	Farmington63640	NCT04423211	Map
MO	Freeman Health System	Joplin64804	NCT04423211	Map
MO	Mercy Hospital Joplin	Joplin64804	NCT04423211	Map
MO	Lake Regional Hospital	Osage Beach65065	NCT04423211	Map
MO	Mercy Clinic-Rolla-Cancer and Hematology	Rolla65401	NCT04423211	Map
MO	Phelps Health Delbert Day Cancer Institute	Rolla65401	NCT04423211	Map
MO	Heartland Regional Medical Center	Saint Joseph64506	NCT04423211	Map
MO	Sainte Genevieve County Memorial Hospital	Sainte Genevieve63670	NCT04423211	Map
MO	CoxHealth South Hospital	Springfield65807	NCT04423211	Map
MO	Mercy Hospital Springfield	Springfield65804	NCT04423211	Map
MO	Mercy Hospital Saint Louis	St Louis63141	NCT04423211	Map
MO	Mercy Hospital South	St Louis63128	NCT04423211	Map
MO	Missouri Baptist Medical Center	St Louis63131	NCT04423211	Map
MO	Saint Louis	St Louis63108-1495	NCT05862272	Map
MO	Siteman Cancer Center at Christian Hospital	St Louis63136	NCT04423211	Map
MO	Siteman Cancer Center-South County	St Louis63129	NCT04423211	Map
MO	St Louis	St Louis63141	NCT05862272	Map
MO	Washington University School of Medicine	St Louis63110	NCT04423211	Map
MO	Missouri Baptist Sullivan Hospital	Sullivan63080	NCT04423211	Map
MO	BJC Outpatient Center at Sunset Hills	Sunset Hills63127	NCT04423211	Map
MT	Billings Clinic Cancer Center	Billings59101	NCT04423211	Map
MT	Bozeman Health Deaconess Hospital	Bozeman59715	NCT04423211	Map
MT	Benefis Sletten Cancer Institute	Great Falls59405	NCT04423211	Map
MT	Great Falls Clinic	Great Falls59405	NCT04423211	Map
MT	Hi-Line Sletten Cancer Center	Havre59501	NCT04423211	Map
MT	Logan Health Medical Center	Kalispell59901	NCT04423211	Map
MT	Community Medical Center	Missoula59804	NCT04423211	Map
MT	Saint Patrick Hospital - Community Hospital	Missoula59802	NCT04423211	Map
NE	Grand Island	Grand Island68803-4327	NCT05862272	Map
NE	CHI Health Good Samaritan	Kearney68847	NCT04423211	Map
NE	Norfolk	Norfolk68701	NCT05862272	Map
NE	Alegent Health Bergan Mercy Medical Center	Omaha68124	NCT04423211	Map
NE	Creighton University Medical Center	Omaha68131	NCT04423211	Map
NV	Las Vegas	Las Vegas89109	NCT05862272	Map
NV	North Las Vegas	North Las Vegas89030	NCT05862272	Map
NJ	Cooper Hospital University Medical Center	Camden08103	NCT04423211	Map
NJ	Rutgers Cancer Institute of New Jersey	New Brunswick08903	NCT04423211	Map
NJ	Robert Wood Johnson University Hospital Somerset	Somerville08876	NCT04423211	Map
NJ	Community Medical Center	Toms River08755	NCT04423211	Map
NJ	MD Anderson Cancer Center at Cooper-Voorhees	Voorhees Township08043	NCT04423211	Map
NJ	West New York	West New York07093-2622	NCT05862272	Map
NY	Northwell Health Imbert Cancer Center	Bay Shore11706	NCT04423211	Map
NY	Northwell Health Physicians Partners Radiation Medicine at Queens	Forest Hills11375	NCT04423211	Map
NY	Northwell Health/Center for Advanced Medicine	Lake Success11042	NCT04423211	Map
NY	Lenox Hill Hospital	New York10075	NCT04423211	Map
NY	Manhattan Eye Ear and Throat Hospital	New York10065	NCT04423211	Map
NY	Memorial Sloan Kettering Cancer Center	New York10017	NCT06111781	Map
NY	Mount Sinai Chelsea	New York10011	NCT04423211	Map
NY	Mount Sinai Hospital	New York10029	NCT04423211	Map
NY	Mount Sinai Union Square	New York10003	NCT04423211	Map
NY	Mount Sinai West	New York10019	NCT04423211	Map
NY	New York Proton Center	New York10035	NCT04423211	Map
NY	NYU Langone Health	New York10016	NCT06397703	Map
NY	Queens Cancer Center	Rego Park11374	NCT04423211	Map
NY	Phelps Memorial Hospital Center	Sleepy Hollow10591	NCT04423211	Map
NY	Stony Brook University Medical Center	Stony Brook11794	NCT04423211	Map
NY	Montefiore Medical Center - Moses Campus	The Bronx10467	NCT04423211	Map
NY	Montefiore Medical Center-Einstein Campus	The Bronx10461	NCT04423211	Map
NY	Montefiore Medical Center-Weiler Hospital	The Bronx10461	NCT04423211	Map
NY	Westchester Medical Center	Valhalla10595	NCT04423211	Map
NC	Durham	Durham27713	NCT05862272	Map
NC	Durham VA Medical Center, Durham, NC	Durham27705	NCT04787744	Map
NC	ECU Health Oncology Kinston	Kinston28501	NCT04423211	Map
NC	New Bern	New Bern28562	NCT05862272	Map
NC	Raleigh	Raleigh27607	NCT05862272	Map
NC	Raleigh	Raleigh27612-8104	NCT05862272	Map
NC	PPD	Wilmington28401	NCT05739123	Map
NC	Winston Salem	Winston-Salem27103-1749	NCT05862272	Map
OH	Bethesda North Hospital	Cincinnati45242	NCT04423211	Map
OH	Cincinnati	Cincinnati45255	NCT05862272	Map
OH	Good Samaritan Hospital - Cincinnati	Cincinnati45220	NCT04423211	Map
OH	Cleveland	Cleveland44124	NCT05862272	Map
OH	Louis Stokes VA Medical Center, Cleveland, OH	Cleveland44106	NCT04787744	Map
OH	Columbus	Columbus43213	NCT05862272	Map
OH	Columbus	Columbus43231	NCT05862272	Map
OH	Ohio State University Comprehensive Cancer Center	Columbus43210	NCT04423211	Map
OH	Ohio State University Comprehensive Cancer Center	Columbus43210	NCT06330805	Map
OH	Dublin	Dublin43016	NCT05862272	Map
OH	Englewood	Englewood45322	NCT05862272	Map
OH	Middletown	Middletown45005-2593	NCT05862272	Map
OK	Mercy Hospital Oklahoma City	Oklahoma City73120	NCT04423211	Map
OK	Stephenson Cancer Center at OU Health, University of Oklahoma Health Sciences Center (SCC-OUHSC)	Oklahoma City73104	NCT06130995	Map
OK	University of Oklahoma Health Sciences Center	Oklahoma City73104	NCT04423211	Map
OR	Saint Charles Health System	Bend97701	NCT04423211	Map
OR	Clackamas Radiation Oncology Center	Clackamas97015	NCT04423211	Map
OR	Bay Area Hospital	Coos Bay97420	NCT04423211	Map
OR	Providence Newberg Medical Center	Newberg97132	NCT04423211	Map
OR	Providence Willamette Falls Medical Center	Oregon City97045	NCT04423211	Map
OR	Oregon Health & Science University	Portland97239	NCT07111247	Map
OR	Oregon Health and Science University	Portland97239	NCT04423211	Map
OR	Providence Portland Medical Center	Portland97213	NCT04423211	Map
OR	Providence Saint Vincent Medical Center	Portland97225	NCT04423211	Map
PA	UPMC Altoona	Altoona16601	NCT04423211	Map
PA	UPMC-Heritage Valley Health System Beaver	Beaver15009	NCT04423211	Map
PA	Carlisle Regional Cancer Center	Carlisle17015	NCT04423211	Map
PA	Erie	Erie16507-1423	NCT05862272	Map
PA	UPMC Hillman Cancer Center Erie	Erie16505	NCT04423211	Map
PA	UPMC Cancer Center at UPMC Horizon	Farrell16121	NCT04423211	Map
PA	UPMC Cancer Centers - Arnold Palmer Pavilion	Greensburg15601	NCT04423211	Map
PA	UPMC Pinnacle Cancer Center/Community Osteopathic Campus	Harrisburg17109	NCT04423211	Map
PA	Penn State Milton S Hershey Medical Center	Hershey17033-0850	NCT04423211	Map
PA	UPMC-Johnstown/John P. Murtha Regional Cancer Center	Johnstown15901	NCT04423211	Map
PA	UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion	Mechanicsburg17050	NCT04423211	Map
PA	UPMC Cancer Center - Monroeville	Monroeville15146	NCT04423211	Map
PA	UPMC Hillman Cancer Center in Coraopolis	Moon Township15108	NCT04423211	Map
PA	UPMC Cancer Center-Natrona Heights	Natrona Heights15065	NCT04423211	Map
PA	UPMC Hillman Cancer Center - New Castle	New Castle16105	NCT04423211	Map
PA	Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA	Philadelphia19104-4551	NCT04787744	Map
PA	Penn Presbyterian Medical Center	Philadelphia19104	NCT04423211	Map
PA	Philadelphia	Philadelphia19104	NCT05862272	Map
PA	Philadelphia	Philadelphia19114	NCT05862272	Map
PA	Thomas Jefferson University Hospital	Philadelphia19107	NCT04423211	Map
PA	University of Pennsylvania/Abramson Cancer Center	Philadelphia19104	NCT04423211	Map
PA	University of Pittsburgh Cancer Institute (UPCI)	Pittsburgh15232	NCT04423211	Map
PA	UPMC-Magee Womens Hospital	Pittsburgh15213	NCT04423211	Map
PA	UPMC-Passavant Hospital	Pittsburgh15237	NCT04423211	Map
PA	UPMC-Saint Clair Hospital Cancer Center	Pittsburgh15243	NCT04423211	Map
PA	UPMC-Saint Margaret	Pittsburgh15215	NCT04423211	Map
PA	UPMC-Shadyside Hospital	Pittsburgh15232	NCT04423211	Map
PA	UPMC Cancer Center at UPMC Northwest	Seneca16346	NCT04423211	Map
PA	UPMC Cancer Center-Uniontown	Uniontown15401	NCT04423211	Map
PA	UPMC Uniontown Hospital Radiation Oncology	Uniontown15401	NCT04423211	Map
PA	UPMC Washington Hospital Radiation Oncology	Washington15301	NCT04423211	Map
PA	UPMC Susquehanna	Williamsport17701	NCT04423211	Map
PA	Main Line Health	Wynnewood19096	NCT06439524	Map
PA	UPMC Memorial	York17408	NCT04423211	Map
SC	Bluffton	Bluffton29910-4883	NCT05862272	Map
SC	Medical University of South Carolina	Charleston29425	NCT04423211	Map
SC	Greenville	Greenville29615-4833	NCT05862272	Map
SC	Summerville	Summerville29485-8345	NCT05862272	Map
SC	West Columbia	West Columbia29169	NCT05862272	Map
TN	Chattanooga	Chattanooga37404	NCT05862272	Map
TN	Jackson	Jackson38305	NCT05862272	Map
TN	Memphis	Memphis38119	NCT05862272	Map
TN	Memphis	Memphis38120	NCT05862272	Map
TX	Arlington	Arlington76012-4705	NCT05862272	Map
TX	Dallas	Dallas75230-2598	NCT05862272	Map
TX	Dallas	Dallas75230	NCT05862272	Map
TX	Parkland Memorial Hospital	Dallas75235	NCT04423211	Map
TX	UT Southwestern Simmons Cancer Center - RedBird	Dallas75237	NCT04423211	Map
TX	UT Southwestern/Simmons Cancer Center-Dallas	Dallas75390	NCT04423211	Map
TX	Fort Worth	Fort Worth76104-4141	NCT05862272	Map
TX	Tarrant County Hospital District/JPS Health Network	Fort Worth76104	NCT04423211	Map
TX	UT Southwestern/Simmons Cancer Center-Fort Worth	Fort Worth76104	NCT04423211	Map
TX	Galveston	Galveston77555	NCT05862272	Map
TX	Houston	Houston77021	NCT05862272	Map
TX	Houston	Houston77024	NCT05862272	Map
TX	Houston	Houston77030-4514	NCT05862272	Map
TX	Houston	Houston77054	NCT05862272	Map
TX	Michael E. DeBakey VA Medical Center, Houston, TX	Houston77030	NCT04787744	Map
TX	League City	League City77573	NCT05862272	Map
TX	Pearland	Pearland77584	NCT05862272	Map
TX	UT Southwestern Clinical Center at Richardson/Plano	Richardson75080	NCT04423211	Map
TX	San Antonio	San Antonio78230	NCT05862272	Map
TX	San Antonio	San Antonio78258	NCT05862272	Map
TX	Sugar Land	Sugar Land77479-1001	NCT05862272	Map
TX	Sugar Land	Sugar Land77479	NCT05862272	Map
TX	Webster	Webster77598-4081	NCT05862272	Map
UT	Pleasant Grove	Pleasant Grove84062-4097	NCT05862272	Map
UT	Huntsman Cancer Institute at University of Utah	Salt Lake City84112	NCT07216248	Map
UT	Salt Lake City	Salt Lake City84107	NCT05862272	Map
VA	Annandale	Annandale22003-7308	NCT05862272	Map
VA	University of Virginia Cancer Center	Charlottesville22908	NCT04423211	Map
VA	Newport News	Newport News23606	NCT05862272	Map
VA	Hunter Holmes McGuire VA Medical Center, Richmond, VA	Richmond23249	NCT04787744	Map
VA	VCU Massey Comprehensive Cancer Center	Richmond23298	NCT04423211	Map
VA	Virginia Beach	Virginia Beach23456-8125	NCT05862272	Map
WA	Providence Regional Cancer System-Aberdeen	Aberdeen98520	NCT04423211	Map
WA	PeaceHealth Saint Joseph Medical Center	Bellingham98225	NCT04423211	Map
WA	Providence Regional Cancer System-Centralia	Centralia98531	NCT04423211	Map
WA	Swedish Cancer Institute-Edmonds	Edmonds98026	NCT04423211	Map
WA	Providence Regional Cancer Partnership	Everett98201	NCT04423211	Map
WA	Swedish Cancer Institute-Issaquah	Issaquah98029	NCT04423211	Map
WA	Kadlec Clinic Hematology and Oncology	Kennewick99336	NCT04423211	Map
WA	Providence Regional Cancer System-Lacey	Lacey98503	NCT04423211	Map
WA	PeaceHealth Saint John Medical Center	Longview98632	NCT04423211	Map
WA	Skagit Regional Health Cancer Care Center	Mount Vernon98274	NCT04423211	Map
WA	FHCC at Northwest Hospital	Seattle98133	NCT04423211	Map
WA	Fred Hutchinson Cancer Center	Seattle98109	NCT04423211	Map
WA	Seattle	Seattle98105-4028	NCT05862272	Map
WA	Swedish Medical Center-Ballard Campus	Seattle98107	NCT04423211	Map
WA	Swedish Medical Center-Cherry Hill	Seattle98122-5711	NCT04423211	Map
WA	Swedish Medical Center-First Hill	Seattle98122	NCT04423211	Map
WA	University of Washington	Seattle98109	NCT06111781	Map
WA	University of Washington Medical Center - Montlake	Seattle98195	NCT04423211	Map
WA	PeaceHealth United General Medical Center	Sedro-Woolley98284	NCT04423211	Map
WA	Saint Michael Cancer Center	Silverdale98383	NCT04423211	Map
WA	Cancer Care Northwest - Spokane South	Spokane99202	NCT04423211	Map
WA	Cancer Care Northwest-North Spokane	Spokane99218	NCT04423211	Map
WA	PeaceHealth Southwest Medical Center	Vancouver98664	NCT04423211	Map
WA	Providence Saint Mary Regional Cancer Center	Walla Walla99362	NCT04423211	Map
WI	Langlade Hospital and Cancer Center	Antigo54409	NCT04423211	Map
WI	Marshfield Medical Center-EC Cancer Center	Eau Claire54701	NCT04423211	Map
WI	University of Wisconsin Carbone Cancer Center - Johnson Creek	Johnson Creek53038	NCT04423211	Map
WI	University of Wisconsin Carbone Cancer Center - Eastpark Medical Center	Madison53718	NCT04423211	Map
WI	University of Wisconsin Carbone Cancer Center - University Hospital	Madison53792	NCT04423211	Map
WI	William S Middleton VA Medical Center	Madison53705	NCT04423211	Map
WI	William S. Middleton Memorial Veterans Hospital, Madison, WI	Madison53705-2254	NCT04787744	Map
WI	Marshfield Medical Center-Marshfield	Marshfield54449	NCT04423211	Map
WI	Clement J. Zablocki VA Medical Center, Milwaukee, WI	Milwaukee53295-1000	NCT04787744	Map
WI	Marshfield Medical Center - Minocqua	Minocqua54548	NCT04423211	Map
WI	Cancer Center of Western Wisconsin	New Richmond54017	NCT04423211	Map
WI	Aspirus Cancer Care - James Beck Cancer Center	Rhinelander54501	NCT04423211	Map
WI	Marshfield Medical Center-Rice Lake	Rice Lake54868	NCT04423211	Map
WI	Aspirus Cancer Care - Stevens Point	Stevens Point54481	NCT04423211	Map
WI	Marshfield Medical Center-River Region at Stevens Point	Stevens Point54482	NCT04423211	Map
WI	Aspirus Regional Cancer Center	Wausau54401	NCT04423211	Map
WI	Marshfield Medical Center - Weston	Weston54476	NCT04423211	Map
WI	Aspirus Cancer Care - Wisconsin Rapids	Wisconsin Rapids54494	NCT04423211	Map
WY	Memorial Hospital of Laramie County	Cheyenne82001	NCT04423211	Map

Relugolix clinical trials at a glance: phase × recruitment status

Phase	recruiting	active not recruiting	completed	terminated	withdrawn	not yet recruiting	unknown	Total
Early P1			1					1
P1	2		3	1				6
P1/P2							1	1
P2	10	4	2		1	1		18
P2/P3	1							1
P3	6	2	12					20
P4	1							1
N/A	2	2	1					5

Recruiting Relugolix clinical trials (23)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT ID	Title	Phase	Indication	Enrollment	Started
NCT06111313	The University of Miami Adapt (UAdapt) Trial	P2	Prostate Cancer	130	Nov 2024
NCT05739123	Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring	—	Pregnancy Related	728	May 2023
NCT04423211	Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging	P3	Biochemically Recurrent Prostate Carcinoma	804	Oct 2020
NCT06499870	Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial	P2	Prostate Adenocarcinoma	50	Sep 2024
NCT07216248	OPTIMASOptimal PSA Triggered Individual Management of Androgen Sensitive Prostate Cancer	P2	Metastatic Hormone-sensitive Prostate Cancer (mHSPC)	160	Oct 2025
NCT06397703	ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer	P2	Prostate Cancer	392	Apr 2024
NCT06378866	DIVINEStereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial	P2	Recurrent Castration-Sensitive Prostate Carcinoma	532	Jun 2024
NCT07455903	Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT	P2	Prostate Cancer	50	Apr 2026
NCT05862272	A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis	P3	Uterine Fibroids	1,000	Aug 2023
NCT06130995	Relugolix + Enzalutamide Study in High-Risk Prostate Cancer	P1	Androgen Deprivation Therapy	46	Dec 2024
NCT06650579	AAREVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial	P3	Recurrent Prostate Carcinoma	72	Jan 2025
NCT04787744	VA STARPORTVeterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer	P2/P3	Prostate Cancer	464	Jul 2021
NCT07100782	Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain	P3	Endometriosis	130	Dec 2025
NCT06111781	The SUGAR Study; SBRT and Relugolix) for Prostate Cancer	P2	Prostate Cancer	60	Apr 2024
NCT05765500	RecoverPC: Relugolix vs GnRH Agonist in Quality of Life	P2	Prostate Cancer	110	Feb 2024
NCT06330805	Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer	P2	Prostate Adenocarcinoma	70	Aug 2024
NCT07111247	Insights in Endocervical Mucus Secretion	P4	Cervical Mucus	15	Jan 2026
NCT06953076	MySaturnUltrasound Transformation of Myomas During Relugolix-Estradiol-Norethisterone Treatment: The MySaturn Study	—	Uterine Bleeding	111	May 2025
NCT06671548	Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids	P3	Heavy Menstrual Bleeding	120	Jan 2024
NCT07025369	Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial	P2	Prostate Adenocarcinoma	30	Aug 2025
NCT06129851	Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer	P2	Stage IIC Prostate Cancer AJCC v8	90	Nov 2023
NCT06439524	The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial	P3	Endometriosis	110	Aug 2024
NCT06631521	Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer	P1	Prostate CA	30	Oct 2024

Relugolix clinical trials by indication

Prostate Cancer (14)

NCT	Acronym	Phase	Status	Title
NCT06111313	—	P2	recruiting	The University of Miami Adapt (UAdapt) Trial
NCT06397703	—	P2	recruiting	ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer
NCT07455903	—	P2	recruiting	Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT
NCT04787744	VA STARPORT	P2/P3	recruiting	Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer
NCT06463457	ADT	P2	active not recruiting	Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and Darolutamide (CLEARED)
NCT06111781	—	P2	recruiting	The SUGAR Study; SBRT and Relugolix) for Prostate Cancer
NCT05765500	—	P2	recruiting	RecoverPC: Relugolix vs GnRH Agonist in Quality of Life
NCT05467176	OPTYX	N/A	active not recruiting	A Multi-Center, Prospective, Observational Study of Patients Being Treated With ORGOVYX
+ 6 more, see All trials below.

Prostate Adenocarcinoma (5)

NCT	Acronym	Phase	Status	Title
NCT04513717	—	P3	active not recruiting	Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial
NCT06499870	—	P2	recruiting	Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial
NCT06330805	—	P2	recruiting	Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer
NCT07025369	—	P2	recruiting	Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial
NCT05050084	—	P3	active not recruiting	Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial

Heavy Menstrual Bleeding (4)

NCT	Acronym	Phase	Status	Title
NCT06671548	—	P3	recruiting	Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
NCT03412890	LIBERTY EXTENSION	P3	completed	LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
NCT03103087	LIBERTY 2	P3	completed	LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
NCT03049735	LIBERTY 1	P3	completed	LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Endometriosis (3)

NCT	Acronym	Phase	Status	Title
NCT07100782	—	P3	recruiting	Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain
NCT06439524	—	P3	recruiting	The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial
NCT03654274	SPIRIT EXTENSION	P3	completed	SPIRIT EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Endometriosis-Associated Pain

Uterine Fibroids (3)

NCT	Acronym	Phase	Status	Title
NCT05862272	—	P3	recruiting	A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
NCT02655237	TAK-385	P3	completed	A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids
NCT02655224	TAK-385	P3	completed	A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids

Pregnancy Related (2)

NCT	Acronym	Phase	Status	Title
NCT05739123	—	N/A	recruiting	Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring
NCT05739136	—	N/A	active not recruiting	MYFEMBREE®: A Retrospective Cohort Study Using an Administrative Healthcare Database to Assess Pregnancy Outcomes in Women Treated With Relugolix Combination Therapy

Biochemically Recurrent Prostate Carcinoma (2)

NCT	Acronym	Phase	Status	Title
NCT04423211	—	P3	recruiting	Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
NCT05320406	REVELUTION	P2	active not recruiting	RElugolix VErsus LeUprolide Cardiac Trial

Healthy (2)

NCT	Acronym	Phase	Status	Title
NCT04714554	—	P1	completed	A Study of the Effects of Erythromycin on the Pharmacokinetics of Relugolix, Estradiol, and Norethindrone in Healthy Postmenopausal Women and on the Pharmacokinetics of Relugolix in Healthy Adult Men
NCT04978688	—	P1	completed	Study of Relugolix Alone and Relugolix Combined With Hormonal Add-Back Therapy in Healthy Premenopausal Female Participants

Endometriosis Related Pain (2)

NCT	Acronym	Phase	Status	Title
NCT03204331	SPIRIT 2	P3	completed	SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain
NCT03204318	SPIRIT 1	P3	completed	SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

Cervical Mucus (1)

NCT	Acronym	Phase	Status	Title
NCT07111247	—	P4	recruiting	Insights in Endocervical Mucus Secretion

Prostate Cancer (Adenocarcinoma) (1)

NCT	Acronym	Phase	Status	Title
NCT07302451	REDI-CaP	P2	active not recruiting	REDI-CaP(Recovery of Erectile Dysfunction Induced in Prostate Cancer Patients)

Metastatic Hormone-sensitive Prostate Cancer (mHSPC) (1)

NCT	Acronym	Phase	Status	Title
NCT07216248	OPTIMAS	P2	recruiting	Optimal PSA Triggered Individual Management of Androgen Sensitive Prostate Cancer

Uterine Bleeding (1)

NCT	Acronym	Phase	Status	Title
NCT06953076	MySaturn	N/A	recruiting	Ultrasound Transformation of Myomas During Relugolix-Estradiol-Norethisterone Treatment: The MySaturn Study

Recurrent Prostate Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT06650579	AA	P3	recruiting	REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial

Androgen Deprivation Therapy (1)

NCT	Acronym	Phase	Status	Title
NCT06130995	—	P1	recruiting	Relugolix + Enzalutamide Study in High-Risk Prostate Cancer

Prostate CA (1)

NCT	Acronym	Phase	Status	Title
NCT06631521	—	P1	recruiting	Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer

Recurrent Castration-Sensitive Prostate Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT06378866	DIVINE	P2	recruiting	Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

Hypogonadism, Male (1)

NCT	Acronym	Phase	Status	Title
NCT06312761	OralT12	P1/P2	unknown	Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17

Pelvic Pain (1)

NCT	Acronym	Phase	Status	Title
NCT06279195	—	P2	withdrawn	Phenotyping of Idiopathic Pelvic Pain With Real-time Uterine Imaging and Relugolix-Combination Therapy Treatment

Stage IIC Prostate Cancer AJCC v8 (1)

NCT	Acronym	Phase	Status	Title
NCT06129851	—	P2	not yet recruiting	Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer

Oligometastatic Prostate Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT05053152	—	P2	active not recruiting	Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, The NRG Promethean Study

Contraception (1)

NCT	Acronym	Phase	Status	Title
NCT04756037	SERENE	P3	completed	Study of the Safety and Contraceptive Efficacy of Relugolix Combination Therapy in Women With Uterine Fibroids or Endometriosis Who Are at Risk for Pregnancy

Metastatic Castration-Resistant Prostate Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT04666129	—	P1	completed	Study of Relugolix in Men With Metastatic Castration-Sensitive Prostate Cancer or Non-Metastatic or Metastatic Castration-Resistant Prostate Cancer

Prostatic Neoplasms (1)

NCT	Acronym	Phase	Status	Title
NCT04523207	ADT	P2	completed	A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for Metastases

Uterine Leiomyoma (1)

NCT	Acronym	Phase	Status	Title
NCT03751124	—	P3	completed	Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Relugolix pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

Acronym	NCT	Phase	Status	Indication	Enrollment	PubMed
AA	NCT06650579	P3	recruiting	Recurrent Prostate Carcinoma	72	—
SERENE	NCT04756037	P3	completed	Contraception	1,164	PMID 37103532
SPIRIT EXTENSION	NCT03654274	P3	completed	Endometriosis	802	PMID 38243752
HERO	NCT03085095	P3	completed	Prostate Cancer	1,134	PMID 35587650
SPIRIT 2	NCT03204331	P3	completed	Endometriosis Related Pain	623	PMID 37283994
SPIRIT 1	NCT03204318	P3	completed	Endometriosis Related Pain	638	PMID 31069056
LIBERTY EXTENSION	NCT03412890	P3	completed	Heavy Menstrual Bleeding	477	—
LIBERTY 2	NCT03103087	P3	completed	Heavy Menstrual Bleeding	382	PMID 35675604
LIBERTY 1	NCT03049735	P3	completed	Heavy Menstrual Bleeding	388	PMID 39466126
TAK-385	NCT02655237	P3	completed	Uterine Fibroids	281	PMID 30741797
TAK-385	NCT02655224	P3	completed	Uterine Fibroids	65	PMID 31594635
OPTIMAS	NCT07216248	P2	recruiting	Metastatic Hormone-sensitive Prostate Cancer (mHSPC)	160	—
DIVINE	NCT06378866	P2	recruiting	Recurrent Castration-Sensitive Prostate Carcinoma	532	—
REDI-CaP	NCT07302451	P2	active not recruiting	Prostate Cancer (Adenocarcinoma)	50	—
ADT	NCT06463457	P2	active not recruiting	Prostate Cancer	33	—
REVELUTION	NCT05320406	P2	active not recruiting	Biochemically Recurrent Prostate Carcinoma	94	PMID 41706486
ADT	NCT04523207	P2	completed	Prostatic Neoplasms	108	PMID 39088398

Terminated and withdrawn Relugolix trials (2)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

NCT06279195withdrawnPhenotyping of Idiopathic Pelvic Pain With Real-time Uterine Imaging and Relugolix-Combination Therapy Treatment
NCT05679388terminatedA Study of Extending Relugolix Dosing Intervals Through Addition of Itraconazole or Ritonavir in Prostate Cancer Patients

All Relugolix trials (53)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT ID	Acronym	Title	Phase	Status	Enrollment	Sponsor	Started
NCT04513717		Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial	P3	active not recruiting	2,753	NRG Oncology	Jan 2021
NCT06111313		The University of Miami Adapt (UAdapt) Trial	P2	recruiting	130	University of Miami	Nov 2024
NCT05739123		Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring	—	recruiting	728	Sumitomo Pharma Switzerland GmbH	May 2023
NCT04423211		Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging	P3	recruiting	804	ECOG-ACRIN Cancer Research Group	Oct 2020
NCT06499870		Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial	P2	recruiting	50	Sean Sachdev	Sep 2024
NCT07216248	OPTIMAS	Optimal PSA Triggered Individual Management of Androgen Sensitive Prostate Cancer	P2	recruiting	160	University of Utah	Oct 2025
NCT06397703		ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer	P2	recruiting	392	NYU Langone Health	Apr 2024
NCT06378866	DIVINE	Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial	P2	recruiting	532	Mayo Clinic	Jun 2024
NCT07302451	REDI-CaP	REDI-CaP(Recovery of Erectile Dysfunction Induced in Prostate Cancer Patients)	P2	active not recruiting	50	National Cancer Institute, Naples	Dec 2025
NCT07455903		Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT	P2	recruiting	50	Baptist Health South Florida	Apr 2026
NCT05862272		A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis	P3	recruiting	1,000	Sumitomo Pharma Switzerland GmbH	Aug 2023
NCT06130995		Relugolix + Enzalutamide Study in High-Risk Prostate Cancer	P1	recruiting	46	University of Oklahoma	Dec 2024
NCT06650579	AA	REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial	P3	recruiting	72	Emory University	Jan 2025
NCT04787744	VA STARPORT	Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer	P2/P3	recruiting	464	VA Office of Research and Development	Jul 2021
NCT05053152		Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, The NRG Promethean Study	P2	active not recruiting	194	NRG Oncology	Apr 2022
NCT06463457	ADT	Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and Darolutamide (CLEARED)	P2	active not recruiting	33	Atish Choudhury, MD	Dec 2024
NCT07100782		Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain	P3	recruiting	130	University of Michigan	Dec 2025
NCT06111781		The SUGAR Study; SBRT and Relugolix) for Prostate Cancer	P2	recruiting	60	Yale University	Apr 2024
NCT05765500		RecoverPC: Relugolix vs GnRH Agonist in Quality of Life	P2	recruiting	110	Dana-Farber Cancer Institute	Feb 2024
NCT06330805		Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer	P2	recruiting	70	Ohio State University Comprehensive Cancer Center	Aug 2024
NCT07111247		Insights in Endocervical Mucus Secretion	P4	recruiting	15	Oregon Health and Science University	Jan 2026
NCT05739136		MYFEMBREE®: A Retrospective Cohort Study Using an Administrative Healthcare Database to Assess Pregnancy Outcomes in Women Treated With Relugolix Combination Therapy	—	active not recruiting	530	Sumitomo Pharma Switzerland GmbH	Apr 2025
NCT06953076	MySaturn	Ultrasound Transformation of Myomas During Relugolix-Estradiol-Norethisterone Treatment: The MySaturn Study	—	recruiting	111	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	May 2025
NCT06671548		Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids	P3	recruiting	120	Qilu Pharmaceutical Co., Ltd.	Jan 2024
NCT07025369		Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial	P2	recruiting	30	Mayo Clinic	Aug 2025
NCT05050084		Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial	P3	active not recruiting	2,050	NRG Oncology	Dec 2021
NCT05320406	REVELUTION	RElugolix VErsus LeUprolide Cardiac Trial	P2	active not recruiting	94	Emory University	Jun 2022
NCT06129851		Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer	P2	not yet recruiting	90	University of Kansas Medical Center	Nov 2023
NCT06439524		The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial	P3	recruiting	110	Main Line Health	Aug 2024
NCT05467176	OPTYX	A Multi-Center, Prospective, Observational Study of Patients Being Treated With ORGOVYX	—	active not recruiting	999	Sumitomo Pharma America, Inc.	Oct 2022
NCT06631521		Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer	P1	recruiting	30	AdventHealth	Oct 2024
NCT04756037	SERENE	Study of the Safety and Contraceptive Efficacy of Relugolix Combination Therapy in Women With Uterine Fibroids or Endometriosis Who Are at Risk for Pregnancy	P3	completed	1,164	Sumitomo Pharma Switzerland GmbH	Mar 2021
NCT06312761	OralT12	Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17	P1/P2	unknown	10	University of Washington	Jun 2024
NCT06279195		Phenotyping of Idiopathic Pelvic Pain With Real-time Uterine Imaging and Relugolix-Combination Therapy Treatment	P2	withdrawn	0	Endeavor Health	Jun 2024
NCT05605964		Randomized Study to Evaluate MACE in Patients With Prostate Cancer Treated With Relugolix or Leuprolide Acetate	P3	completed	387	Sumitomo Pharma America, Inc.	Jan 2023
NCT06462014		Description of Relugolix Use in Patients With Prostate Cancer Within the VHA	—	completed	507	Pfizer	Jun 2024
NCT07069465	PIONEER PSMA	Pilot Study: Androgen Deprivation Therapy Impact on PSMA-PET Sensitivity in Prostatectomy Staging	Early P1	completed	10	Urology Clinics of North Texas	Jun 2024
NCT05679388		A Study of Extending Relugolix Dosing Intervals Through Addition of Itraconazole or Ritonavir in Prostate Cancer Patients	P1	terminated	60	University of Chicago	Feb 2023
NCT04666129		Study of Relugolix in Men With Metastatic Castration-Sensitive Prostate Cancer or Non-Metastatic or Metastatic Castration-Resistant Prostate Cancer	P1	completed	48	Sumitomo Pharma America, Inc.	Feb 2021
NCT04523207	ADT	A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for Metastases	P2	completed	108	Janssen Research & Development, LLC	Aug 2020
NCT03654274	SPIRIT EXTENSION	SPIRIT EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Endometriosis-Associated Pain	P3	completed	802	Myovant Sciences GmbH	May 2018
NCT03085095	HERO	A Study to Evaluate the Safety and Efficacy of Relugolix in Men With Advanced Prostate Cancer	P3	completed	1,134	Myovant Sciences GmbH	Apr 2017
NCT03751124		Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids	P3	completed	229	Myovant Sciences GmbH	Oct 2018
NCT03204331	SPIRIT 2	SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain	P3	completed	623	Myovant Sciences GmbH	Nov 2017
NCT03204318	SPIRIT 1	SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain	P3	completed	638	Myovant Sciences GmbH	Dec 2017
NCT04714554		A Study of the Effects of Erythromycin on the Pharmacokinetics of Relugolix, Estradiol, and Norethindrone in Healthy Postmenopausal Women and on the Pharmacokinetics of Relugolix in Healthy Adult Men	P1	completed	43	Myovant Sciences GmbH	Jan 2021
NCT03412890	LIBERTY EXTENSION	LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids	P3	completed	477	Myovant Sciences GmbH	Oct 2017
NCT03103087	LIBERTY 2	LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids	P3	completed	382	Myovant Sciences GmbH	Jun 2017
NCT03049735	LIBERTY 1	LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids	P3	completed	388	Myovant Sciences GmbH	Apr 2017
NCT02655237	TAK-385	A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids	P3	completed	281	Takeda	Mar 2016
NCT02655224	TAK-385	A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids	P3	completed	65	Takeda	Mar 2016
NCT02083185		A Phase 2 Study to Evaluate the Safety and Efficacy of TAK-385, Together With a Leuprorelin Observational Cohort, in Participants With Prostate Cancer	P2	completed	136	Millennium Pharmaceuticals, Inc.	Mar 2014
NCT04978688		Study of Relugolix Alone and Relugolix Combined With Hormonal Add-Back Therapy in Healthy Premenopausal Female Participants	P1	completed	48	Myovant Sciences GmbH	Jun 2016

Relugolix clinical trials: frequently asked questions

How many Relugolix clinical trials are there?: 53 Relugolix clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 22 are actively recruiting participants. 19 are marked completed.
Are Relugolix clinical trials recruiting in 2026?: Yes — 22 Relugolix trials are actively recruiting in 2026, with 439 U.S. sites across 41 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Relugolix being studied for?: Relugolix is being studied for Prostate Cancer, Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Uterine Fibroids, Heavy Menstrual Bleeding and 54 more. The trials are grouped by indication on this page.
What phase is Relugolix in?: Relugolix clinical trials span 1 Phase 4, 20 Phase 3, 18 Phase 2, 6 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Relugolix clinical trials?: The lead sponsor across the most Relugolix trials is Myovant Sciences GmbH, with 33 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Relugolixas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed June 12, 2026.

Related pages on Hipa.ai:

Relugolix overview Relugolix evidence & publications