How many Olpasiran clinical trials are there?

9 Olpasiran clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 2 are actively recruiting participants. 5 are marked completed.

Are Olpasiran clinical trials recruiting in 2026?

Yes — 2 Olpasiran trials are actively recruiting in 2026, with 205 U.S. sites across 38 states. See the recruiting trials and the per-state site list further down this page.

What conditions is Olpasiran being studied for?

Olpasiran is being studied for Cardiovascular Disease, Atherosclerotic Cardiovascular Disease, Basic Science, Elevated Serum Lipoprotein(a), Hepatic Impairment and 1 more. The trials are grouped by indication on this page.

What phase is Olpasiran in?

Olpasiran clinical trials span 3 Phase 3, 1 Phase 2, 4 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.

Who sponsors Olpasiran clinical trials?

The lead sponsor across the most Olpasiran trials is Amgen. Each trial row links to the full study detail page including sponsor information.

Olpasiran Clinical Trials (2026): 9 Studies for Cardiovascular Disease & Atherosclerotic Cardiovascular Disease

Creator: Hipa.ai Research
Published: 2026-04-27T18:04:26.716Z

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: June 16, 2026.

9 Olpasiran clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 7 indications (including Cardiovascular Disease & Atherosclerotic Cardiovascular Disease) and 19,098 total planned enrollment. 3 Phase 3 Olpasiran trials and 1 Phase 2 are listed. 2 Olpasiran clinical trials are actively recruiting at 205 U.S. sites across 38 states. Most recent activity: NCT07136012 (Oct 2031).

Where to Participate: All Olpasiran Trial Sites in the U.S. (205 sites across 38 states)

Every actively recruiting Olpasirantrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

State	Facility	City	Trial	Map
AL	Advanced Cardiovascular LLC	Alexander City35010	NCT07136012	Map
AL	Birmingham Clinical Research	Birmingham35209	NCT07136012	Map
AL	University of Alabama Birmingham Saint Vincents Birmingham	Birmingham35205	NCT07136012	Map
AL	Alliance For Multispecialty Research - Daphne	Daphne36526	NCT07136012	Map
AL	Eastern Shore Research Institute	Fairhope36532	NCT07136012	Map
AL	Heart Center Research LLC	Huntsville35801	NCT07136012	Map
AL	CB Flock Research Corporation	Mobile36608	NCT07136012	Map
AZ	Elite Clinical Studies LLC	Phoenix85018	NCT07136012	Map
AZ	Hero Clinical Research	Phoenix85021	NCT07136012	Map
AZ	Phoenix Clinical	Phoenix85014	NCT07136012	Map
AZ	HonorHealth Research Institute	Scottsdale85258	NCT07136012	Map
AZ	Eclipse Clinical Research	Tucson85745	NCT07136012	Map
AR	Lynn Institute of the Ozarks	Little Rock72204	NCT07136012	Map
CA	National Heart Institute	Beverly Hills90211	NCT07136012	Map
CA	310 Clinical Research	Inglewood90301	NCT07136012	Map
CA	University of California San Diego	La Jolla92037	NCT07136012	Map
CA	InvivoCure	Los Angeles91405	NCT07136012	Map
CA	Valley Clinical Trials	Northridge91325	NCT07136012	Map
CA	Clinical Trials Research - Sacramento	Roseville95661	NCT07136012	Map
CA	Alliance Clinical Research	San Diego92120	NCT07136012	Map
CA	Encompass Clinical Research	Spring Valley91978	NCT07136012	Map
CA	Stanford Health Care	Stanford94305	NCT07136012	Map
CA	Manshadi Heart Institute	Stockton95204	NCT07136012	Map
CA	Blue Coast Cardiology	Vista92083	NCT07136012	Map
CA	Diablo Clinical Research	Walnut Creek94598	NCT07136012	Map
CA	Focus Clinical Research	West Hills91307	NCT07136012	Map
CA	Interventional Cardiology Medical Group	West Hills91307	NCT07136012	Map
CO	UCHealth Memorial Central	Colorado Springs80909	NCT07136012	Map
CO	South Denver Cardiology Associates	Littleton80120	NCT07136012	Map
CT	Bridgeport Hospital	Bridgeport06610	NCT07293260	Map
CT	Gandelman Cardiology, PC	Greenwich06830	NCT07136012	Map
CT	ClinTrial Hamden	Hamden06518	NCT07136012	Map
CT	Chase Medical Research LLC	Waterbury06708	NCT07136012	Map
FL	Excel Medical Clinical Trials	Boca Raton33434	NCT07136012	Map
FL	Clearwater Cardiovascular Consultants	Clearwater33756	NCT07136012	Map
FL	Proactive Clinical Research	Fort Lauderdale33308	NCT07136012	Map
FL	Elite Cardiac Research Center LLC	Hialeah33013	NCT07136012	Map
FL	Indago Research and Health Center	Hialeah33012	NCT07136012	Map
FL	Jacksonville Center for Clinical Research	Jacksonville32216	NCT07136012	Map
FL	Jacksonville Center for Clinical Research	Jacksonville32216	NCT07293260	Map
FL	East Coast Institute for Research, LLC	Lake City32055	NCT07136012	Map
FL	Columbus Clinical Services LLC	Miami33125	NCT07136012	Map
FL	Kendall South Medical Center	Miami33175	NCT07136012	Map
FL	Inpatient Research Clinic, LLC	Miami Lakes33014	NCT07136012	Map
FL	Panax Clinical Research	Miami Lakes33014	NCT07136012	Map
FL	Eminat, LLC	Miramar33027	NCT07136012	Map
FL	Suncoast Clinical Research Inc	New Port Richey34652	NCT07136012	Map
FL	Ocala Cardiovascular Research	Ocala34471	NCT07136012	Map
FL	Ocala Research Institute, Inc	Ocala34474	NCT07136012	Map
FL	Ormond Beach Clinical Research	Ormond Beach32174	NCT07136012	Map
FL	Baptist Health Care	Pensacola32514	NCT07136012	Map
FL	Denali Health Plant City	Plant City33563	NCT07136012	Map
FL	FWD Clinical Research	Tamarac33321	NCT07136012	Map
GA	Emory University Hospital	Atlanta30322	NCT07136012	Map
GA	East Coast Institute for Research	Canton30114	NCT07136012	Map
GA	Northeast Georgia Medical Center Wisteria Building	Cumming30041	NCT07136012	Map
GA	Nsc Research	Johns Creek30024	NCT07136012	Map
GA	Georgia Clinical Research	Lawrenceville30044	NCT07136012	Map
GA	North Georgia Clinical Research	Woodstock30189	NCT07136012	Map
ID	Solaris Clinical Research	Meridian83646	NCT07136012	Map
ID	St Lukes Idaho Cardiology Associates	Meridian83642	NCT07136012	Map
IL	Endeavor Health-Northwest Community Healthcare	Arlington Heights60005	NCT07136012	Map
IL	Christie Clinic	Champaign61822	NCT07136012	Map
IL	Advocate Lutheran General Hospital	Park Ridge60068	NCT07136012	Map
IL	Alliance for Multispecialty Research LLC - Park Ridge	Park Ridge66068	NCT07136012	Map
IN	MediSphere Medical Research Center LLC	Evansville47714	NCT07136012	Map
IN	Parkview Research Center	Fort Wayne46845	NCT07136012	Map
IN	Ascension Saint Vincent Heart Center	Indianapolis46290	NCT07136012	Map
IN	Franciscan Health Indianapolis	Indianapolis46237	NCT07136012	Map
IN	Cardiovascular Research of Northwest Indiana LLC	Munster46321	NCT07136012	Map
IN	Reid Physician Associates	Richmond47374	NCT07136012	Map
IA	MercyOne Iowa Heart Center	West Des Moines50266	NCT07136012	Map
KS	Hutchinson Clinic PA	Hutchinson67502	NCT07136012	Map
KS	University of Kansas Medical Center	Kansas City66160	NCT07136012	Map
KS	Midwest Heart and Vascular Specialists	Overland Park66211	NCT07136012	Map
KS	Midwest Heart and Vascular Specialists	Overland Park66211	NCT07293260	Map
KY	Graves Gilbert Clinic	Bowling Green42101	NCT07136012	Map
KY	Baptist Health Lexington	Lexington40503	NCT07136012	Map
KY	The Research Group of Lexington LLC	Lexington40503	NCT07136012	Map
LA	Heart Clinic of Hammond	Covington70433	NCT07136012	Map
LA	IMA Clinical Research	Monroe71201	NCT07136012	Map
LA	Louisiana Heart Center	Slidell70458	NCT07136012	Map
LA	Monroe Research LLC	West Monroe71291	NCT07136012	Map
MD	Ascension Saint Agnes Heart Care	Baltimore21229	NCT07136012	Map
MD	Johns Hopkins Hospital	Baltimore21287	NCT07136012	Map
MD	Metropolitan Cardiovascular Consultants LLC	Beltsville20705	NCT07136012	Map
MD	Flourish Bowie	Bowie20715	NCT07293260	Map
MD	Flourish Research	Bowie20715	NCT07136012	Map
MD	Centennial Medical Group	Columbia21045	NCT07136012	Map
MD	Johns Hopkins University	Columbia21044	NCT07136012	Map
MD	Medstar Franklin Square Medical Center	Hyattsville20782	NCT07136012	Map
MD	Capitol Cardiology Associates	Lanham20706	NCT07136012	Map
MA	Brigham and Womens Hospital	Boston02115	NCT07136012	Map
MI	Henry Ford Health System	Detroit48202	NCT07136012	Map
MI	Healthy Heart Cardiology	Grand Rapids49546	NCT07136012	Map
MI	MyMichigan Medical Center Midland - Clinical Research Department	Midland48670	NCT07136012	Map
MI	Advanced Cardiology Associates	Rochester Hills48307	NCT07136012	Map
MI	Revival Research Institute	Southfield48034	NCT07136012	Map
MN	Saint Marys Medical Center	Duluth55805	NCT07136012	Map
MN	Health East Cancer Care	Maplewood55109	NCT07136012	Map
MN	University of Minnesota	Minneapolis55455	NCT07136012	Map
MN	Mayo Clinic	Rochester55905	NCT07136012	Map
MN	Methodist Hospital	Saint Louis Park55426	NCT07136012	Map
MS	Jackson Heart Clinic	Jackson39216	NCT07136012	Map
MS	Cardiology Associates Research LLC	Tupelo38801	NCT07136012	Map
MO	Sisters of Saint Mary Health Heart and Vascular Care	Bridgeton63044	NCT07136012	Map
MO	Kansas City Veterans Affairs Medical Center	Kansas City64128	NCT07136012	Map
MO	Washington University	St Louis63110	NCT07136012	Map
NE	Bryan Heart	Lincoln68506	NCT07136012	Map
NE	Physician Research Collaboration, LLC	Lincoln68516	NCT07136012	Map
NV	American Institute of Medical Research	Las Vegas89123	NCT07136012	Map
NV	Excel Clinical Research	Las Vegas89109	NCT07136012	Map
NV	Las Vegas Clinical Trials	North Las Vegas89030	NCT07136012	Map
NV	Renown Institute for Heart and Vascular Health	Reno89502	NCT07136012	Map
NJ	Advanced Heart Care LLC	Bridgewater08807	NCT07136012	Map
NJ	Advanced Heart and Vascular Institute of Hunterdon	Flemington08822	NCT07136012	Map
NJ	Clinical Reseach Philadelphia Pennington	Hamilton08690	NCT07136012	Map
NJ	Med Clinical Research Partners - Irvington	Irvington07111	NCT07136012	Map
NJ	New Jersey Medcare / New Jersey Heart	Linden07036	NCT07136012	Map
NJ	Saint Michaels Medical Center	Newark07102	NCT07136012	Map
NJ	Circuit Clinical / Optum Medical Care of New Jersey	Secaucus07094	NCT07136012	Map
NJ	The Heart House - Washington Township	Sewell08080	NCT07136012	Map
NJ	CardioMetabolic Collaborative Clinic	Somerset08873	NCT07136012	Map
NJ	Ima Clinical Research - Warren	Warren Township07059	NCT07136012	Map
NY	Albany Medical College	Albany12203	NCT07136012	Map
NY	Basil Clinical	Inwood11096	NCT07136012	Map
NY	Rasai Research	Jackson Heights11372	NCT07136012	Map
NY	Crystal Run Healthcare	Monroe10950	NCT07136012	Map
NY	Icahn School of Medicine at Mount Sinai	New York10029	NCT07136012	Map
NY	Ima Clinical Research Manhattan	New York10036	NCT07136012	Map
NY	Mount Sinai Queens	New York10029	NCT07136012	Map
NY	Niagara Falls Memorial Medical Center	Niagara Falls14304	NCT07136012	Map
NY	Circuit Clinical Orchard Park Family Practice	Orchard Park14127	NCT07136012	Map
NY	Hudson Valley Cardiovascular Physicians PC	Poughkeepsie12601	NCT07136012	Map
NY	Saratoga Clinical Research, LLC	Saratoga Springs12866	NCT07136012	Map
NC	Duke University Health System	Durham27710	NCT07136012	Map
NC	Medication Management LLC	Greensboro27405	NCT07136012	Map
NC	Moses H Cone Memorial Hospital	Greensboro27401	NCT07136012	Map
NC	Triad Clinical Trials, LLC	Greensboro27410	NCT07136012	Map
NC	ClinCept, LLC	Kinston28501	NCT07136012	Map
NC	Monroe Biomedical Research	Monroe28112	NCT07136012	Map
NC	Piedmont Healthcare	Statesville28625	NCT07136012	Map
NC	Accellacare Research of Wilmington	Wilmington28401	NCT07136012	Map
NC	Wake Forest University Health Sciences	Winston-Salem27157	NCT07136012	Map
ND	Lillestol Research LLC	Fargo58104	NCT07136012	Map
OH	Aultman Cardiology Clinical Trials	Canton44710	NCT07136012	Map
OH	The Christ Hospital	Cincinnati45219	NCT07136012	Map
OH	Velocity Clinical Research - Cincinnati	Cincinnati45219	NCT07136012	Map
OH	Nexgen Research	Lima45801	NCT07136012	Map
OH	K and R Research	Marion43302	NCT07136012	Map
OK	Alliance for Multispecialty Research	Norman73069	NCT07136012	Map
PA	Montefiore Medical Center - Bronx	Philadelphia19141	NCT07293260	Map
PA	University of Pennsylvania	Philadelphia19104	NCT07136012	Map
PA	Preferred Primary Care Physicians, Inc	Pittsburgh15236	NCT07136012	Map
PA	Pottstown Medical Specialists Inc	Pottstown19464	NCT07136012	Map
RI	Miriam Hospital	East Greenwich02818	NCT07136012	Map
SC	Medical University of South Carolina	Charleston29425	NCT07136012	Map
SC	Pharmacorp Clinical Trials Inc	Charleston29412	NCT07136012	Map
SC	Prisma Health Carolina Cardiology - Greenville	Gantt29605	NCT07136012	Map
SC	Walker Family Care	Little River29566	NCT07136012	Map
SC	Accellacare Charleston	Mt. Pleasant29464	NCT07136012	Map
SC	Tribe Clinical Research - Spartanburg	Spartanburg29301	NCT07136012	Map
SD	Monument Health Clinical Research	Rapid City57701	NCT07136012	Map
TN	Erlanger Health, Inc.	Chattanooga37403	NCT07136012	Map
TN	Ascension Saint Thomas	Nashville37205	NCT07136012	Map
TN	Parkway Cardiology Associates	Oak Ridge37830	NCT07136012	Map
TN	Tennessee Center for Clinical Trials	Tullahoma37388	NCT07136012	Map
TX	PharmaTex Research, LLC	Amarillo79106	NCT07136012	Map
TX	Ima Clinical Research	Austin78745	NCT07136012	Map
TX	Texas Diabetes and Endocrinology	Austin78731	NCT07136012	Map
TX	Pioneer Medical Associates	Carrollton75007	NCT07136012	Map
TX	Baylor Scott and White Heart and Vascular Hospital-Dallas	Dallas75226	NCT07136012	Map
TX	Cedar Health Research, LLC	Dallas75251	NCT07136012	Map
TX	The Heartbeat Clinic	Dallas75243	NCT07136012	Map
TX	Zenos Clinical Research	Dallas75230	NCT07136012	Map
TX	Cedar Health Research, LLC	Euless76040	NCT07136012	Map
TX	Baylor College of Medicine	Houston77030	NCT07136012	Map
TX	Cardiovascular Specialists of Willowbrook	Houston77070	NCT07136012	Map
TX	East Texas Cardiology PA	Houston77002	NCT07136012	Map
TX	Vital Heart and Vein	Humble77338	NCT07136012	Map
TX	Vital Heart and Vein	Humble77338	NCT07293260	Map
TX	Tcr Institute Llc	Kingwood77339	NCT07136012	Map
TX	Epic Clinical Research	Lewisville75057	NCT07136012	Map
TX	Texas Tech University Health Sciences Center	Lubbock79430	NCT07136012	Map
TX	North Dallas Research Associates	McKinney75069	NCT07136012	Map
TX	Revival Research Institute	McKinney75071	NCT07136012	Map
TX	Texas Institute of Cardiology	McKinney75071	NCT07136012	Map
TX	Southern Endocrinology Associates PA	Mesquite75149	NCT07136012	Map
TX	Orion Medical	Pasadena77505	NCT07136012	Map
TX	Valley Institute of Research Plano	Plano75024	NCT07136012	Map
TX	Ima Clinical Research San Antonio	San Antonio78229	NCT07136012	Map
TX	St Davids Heart & Vascular PLLC dba Austin Heart	San Marcos78666	NCT07136012	Map
TX	Tyler Cardiovascular Consultants	Tyler75701	NCT07136012	Map
UT	Alpine Research Organization	Layton84041	NCT07136012	Map
VA	Inova Cardiology - Fairfax	Fairfax22031	NCT07136012	Map
VA	Virginia Heart	Falls Church22042	NCT07136012	Map
VA	Virginia Heart - Loudoun	Leesburg20176	NCT07136012	Map
VA	Carient Heart and Vascular	Manassas20109	NCT07136012	Map
VA	Bon Secours Cardiology	Midlothian23114	NCT07136012	Map
VA	Tidewater Physicians Multispecialty Group Clinical Research	Newport News23606	NCT07136012	Map
VA	Alliance for Multispecialty Research Norfolk	Norfolk23502	NCT07136012	Map
VA	Centricity Research	Suffolk23435	NCT07136012	Map
VA	Selma Medical Associates	Winchester22601	NCT07136012	Map
WA	Western Washington Medical Group	Everett98208	NCT07136012	Map
WA	Rainier Clinical Research Center	Renton98057	NCT07136012	Map

Olpasiran clinical trials at a glance: phase × recruitment status

Phase	recruiting	active not recruiting	completed	available	Total
P1			4		4
P2			1		1
P3	2	1			3
N/A				1	1

Recruiting Olpasiran clinical trials (2)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT ID	Title	Phase	Indication	Enrollment	Started
NCT07136012	OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events	P3	Cardiovascular Disease	11,000	Aug 2025
NCT07293260	OCEAN(a)-CCTAOlpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial	P3	Cardiovascular Disease	406	Mar 2026

Olpasiran clinical trials by indication

Cardiovascular Disease (3)

NCT	Acronym	Phase	Status	Title
NCT07136012	—	P3	recruiting	OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
NCT07293260	OCEAN(a)-CCTA	P3	recruiting	Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial
NCT04270760	—	P2	completed	Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction - DOSE Finding Study

Basic Science (1)

NCT	Acronym	Phase	Status	Title
NCT06411860	—	P1	completed	A Study to Assess the Effect of Olpasiran on QT/QTc Intervals in Healthy Participants

Atherosclerotic Cardiovascular Disease (1)

NCT	Acronym	Phase	Status	Title
NCT05581303	—	P3	active not recruiting	Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial

Renal Impairment (1)

NCT	Acronym	Phase	Status	Title
NCT05489614	—	P1	completed	A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Normal Renal Function and Participants With Various Degrees of Renal Impairment

Hepatic Impairment (1)

NCT	Acronym	Phase	Status	Title
NCT05481411	—	P1	completed	A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Various Degrees of Hepatic Impairment

Elevated Serum Lipoprotein(a) (1)

NCT	Acronym	Phase	Status	Title
NCT04987320	—	P1	completed	A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Olpasiran in Chinese Participants With Elevated Serum Lipoprotein(a)

Other (1)

NCT	Acronym	Phase	Status	Title
NCT07079267	—	N/A	available	Olpasiran Expanded Access Program

Olpasiran pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

Acronym	NCT	Phase	Status	Indication	Enrollment	PubMed
OCEAN(a)-CCTA	NCT07293260	P3	recruiting	Cardiovascular Disease	406	—

All Olpasiran trials (9)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT ID	Acronym	Title	Phase	Status	Enrollment	Sponsor	Started
NCT07136012		OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events	P3	recruiting	11,000	Amgen	Aug 2025
NCT07293260	OCEAN(a)-CCTA	Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial	P3	recruiting	406	Amgen	Mar 2026
NCT05581303		Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial	P3	active not recruiting	7,297	Amgen	Dec 2022
NCT07079267		Olpasiran Expanded Access Program	—	available	0	Amgen	—
NCT06411860		A Study to Assess the Effect of Olpasiran on QT/QTc Intervals in Healthy Participants	P1	completed	32	Amgen	Sep 2024
NCT05489614		A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Normal Renal Function and Participants With Various Degrees of Renal Impairment	P1	completed	33	Amgen	Sep 2022
NCT05481411		A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Various Degrees of Hepatic Impairment	P1	completed	25	Amgen	Sep 2022
NCT04270760		Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction - DOSE Finding Study	P2	completed	281	Amgen	Jul 2020
NCT04987320		A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Olpasiran in Chinese Participants With Elevated Serum Lipoprotein(a)	P1	completed	24	Amgen	Jul 2021

Olpasiran clinical trials: frequently asked questions

How many Olpasiran clinical trials are there?: 9 Olpasiran clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 2 are actively recruiting participants. 5 are marked completed.
Are Olpasiran clinical trials recruiting in 2026?: Yes — 2 Olpasiran trials are actively recruiting in 2026, with 205 U.S. sites across 38 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Olpasiran being studied for?: Olpasiran is being studied for Cardiovascular Disease, Atherosclerotic Cardiovascular Disease, Basic Science, Elevated Serum Lipoprotein(a), Hepatic Impairment and 1 more. The trials are grouped by indication on this page.
What phase is Olpasiran in?: Olpasiran clinical trials span 3 Phase 3, 1 Phase 2, 4 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Olpasiran clinical trials?: The lead sponsor across the most Olpasiran trials is Amgen. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Olpasiranas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed June 16, 2026.

Related pages on Hipa.ai:

Olpasiran overview