Trial results comparing visual field assessment perimeters for Glaucoma patients were posted on ClinicalTrials.gov on 2026-04-30, indicating that the TEMPO perimeter had a mean total acquisition time of 4.44 minutes, which was notably faster than the other two perimeters tested.
Background
Glaucoma is a group of eye conditions that damage the optic nerve, often due to abnormally high pressure in the eye. It is a leading cause of irreversible blindness worldwide. Regular monitoring of visual fields is crucial for detecting progression and managing the disease, as it helps clinicians assess the extent of vision loss. Traditional visual field tests can be time-consuming and challenging for patients, impacting clinic efficiency and patient compliance. Innovations in perimetry aim to improve the patient experience and streamline the diagnostic process without compromising accuracy.
Trial design
This completed study, identified as Phase 4, enrolled 54 participants with Glaucoma. The trial was a single-center, prospective, randomized, comparative study designed to assess visual field measurements between three different perimeters: TEMPO, VisuALL, and the Humphrey Field Analyzer (HFA). Participants underwent assessments at a single visit. Clinical evaluations included Mean Deviation (MD), Pattern Standard Deviation (PSD), Foveal Threshold (FT), Visual Field Index (VFI), Optical Coherence Tomography (OCT), and a questionnaire.
Key results
The trial compared the performance of the three perimeters across several key measurements:
- Total Acquisition Time (Both Eyes):
- TEMPO had a mean acquisition time of 4.44 minutes (Standard Deviation: 0.88 minutes).
- Humphrey Field Analyzer had a mean acquisition time of 7.34 minutes (Standard Deviation: 2.27 minutes).
- VisuALL had a mean acquisition time of 7.71 minutes (Standard Deviation: 1.21 minutes).
- Mean Deviation (MD):
- TEMPO showed a mean MD of -3.16 dB (Standard Deviation: 4.39 dB).
- Humphrey Field Analyzer showed a mean MD of -3.28 dB (Standard Deviation: 4.19 dB).
- VisuALL showed a mean MD of -4.22 dB (Standard Deviation: 3.51 dB).
- Pattern Standard Deviation (PSD):
- TEMPO showed a mean PSD of 4.78 dB (Standard Deviation: 3.82 dB).
- Humphrey Field Analyzer showed a mean PSD of 4.22 dB (Standard Deviation: 3.21 dB).
- VisuALL showed a mean PSD of 4.51 dB (Standard Deviation: 2.99 dB).
- Foveal Threshold (FT):
- TEMPO showed a mean FT of 31.40 dB (Standard Deviation: 3.77 dB).
- Humphrey Field Analyzer showed a mean FT of 34.71 dB (Standard Deviation: 3.63 dB).
- VisuALL showed a mean FT of 27.61 dB (Standard Deviation: 6.20 dB).
What this means
The results suggest that the TEMPO perimeter offers a significantly faster total acquisition time for visual field assessments compared to the Humphrey Field Analyzer and VisuALL perimeters, with a mean difference of approximately 3 minutes for both eyes. This reduction in test time could improve patient comfort and clinic workflow efficiency, potentially leading to better patient compliance with regular monitoring for glaucoma. While the acquisition time shows a clear difference, the reported mean values for other critical parameters like Mean Deviation, Pattern Standard Deviation, and Foveal Threshold across the three devices show varying results, indicating that clinicians would need to consider the full spectrum of data when evaluating the utility of each perimeter in clinical practice.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT06539715, titled "Comparison of Visual Field Assessments Between Three Perimeters", were posted on 2026-04-30 on clinicaltrials.gov.