Trial results for an initial study evaluating a mobile app pain coping intervention, PainPac, for patients with Colorectal Cancer were posted on ClinicalTrials.gov on 2025-09-04, with 62 participants enrolled.
Background
Patients undergoing oncology treatment, including those with colorectal cancer, often experience significant pain. Effective pain management is crucial for improving quality of life. Traditional pain coping interventions can face barriers related to access and real-time support. The PainPac mobile app aims to address these challenges by leveraging technology to increase patient access to interventions and utilizing real-time assessment. This approach seeks to combine biological and behavioral data to potentially improve outcomes, particularly for patients experiencing pain.
Trial design
This completed study, titled "Initial Testing of a Mobile App Pain Coping Intervention for Outpatient Oncology Settings (PainPac)", enrolled 62 participants with Colorectal Cancer. The trial was designed to assess the feasibility and acceptability of the PainPac intervention. Participants were allocated to either the PainPac mobile app group or a Pain Coping Skills Training (PCST)-Video group. The study did not specify a phase.
Key results
The trial results focused on several key measurements related to feasibility and acceptability:
- Feasibility as Measured by Study Accrual:
- A total of 62 participants were consented.
- Feasibility as Measured by Attrition:
- 2 participants in the PainPac group did not complete the 1-month visit.
- 1 participant in the PCST-Video group did not complete the 1-month visit.
- Feasibility as Measured by Assessment Completion:
- 60 participants completed study baseline assessments.
- 28 participants in the PainPac group completed post-study sessions assessments.
- 27 participants in the PCST-Video group completed post-study sessions assessments.
- 28 participants in the PainPac group completed study 1-month follow-up assessments.
- 29 participants in the PCST-Video group completed study 1-month follow-up assessments.
- A total of 27 participants in the PainPac group completed all four sessions.
- A total of 24 participants in the PCST-Video group completed all four sessions.
- Acceptability as Measured by the Client Satisfaction Questionnaire:
- The PainPac group reported a mean score of 28.11 with a standard deviation of 3.74 units on a scale.
- The PCST-Video group reported a mean score of 28.93 with a standard deviation of 3.57 units on a scale.
What this means
The posted results indicate that the PainPac mobile app intervention demonstrated favorable feasibility and acceptability among patients with colorectal cancer. The study successfully accrued 62 participants, with low attrition and high assessment completion rates, including 27 in the PainPac group completing all four sessions. Both the PainPac group (mean 28.11) and the PCST-Video group (mean 28.93) showed similar and positive scores on the Client Satisfaction Questionnaire, suggesting good acceptability for both interventions. These findings support the potential of mobile health interventions like PainPac for pain coping in oncology settings and warrant further investigation into their efficacy.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05686122, titled "Initial Testing of a Mobile App Pain Coping Intervention for Outpatient Oncology Settings (PainPac)", were posted on 2025-09-04 on clinicaltrials.gov.