Trial results for the "Screen to Save 2: Rural Cancer Screening Educational Intervention" study in Colorectal Cancer were posted on ClinicalTrials.gov on 2026-02-02, with 205 participants enrolled.
Background
Colorectal cancer remains a significant public health concern, and early detection through screening is critical for improving patient outcomes. Educational interventions play a vital role in increasing awareness, promoting screening uptake, and addressing knowledge gaps regarding risk factors and prevention strategies, especially in rural communities where access to information and healthcare resources may be limited. This study aimed to enhance understanding of effective educational approaches for cancer screening.
Trial design
This completed study, designated as Phase NA, enrolled 205 participants. The trial investigated conditions including Cancer and Colorectal Cancer, focusing on an educational intervention designed to help people understand cancer screening. The study's purpose was to understand how to educate people about cancer screening.
Key results
The trial reported changes in correct responses regarding knowledge related to colorectal cancer risk, prevention, and screening in the Experimental Arm 1. Observed individual percent changes in knowledge ranged from -.5% to 24%. Key analyses using a t-test (2-sided) showed statistically significant changes in knowledge for several specific areas:
- Change in knowledge for the survey question "What is Lynch syndrome" showed a p-value of 0.0001.
- Change in knowledge related to the risk factor "Poor diet" showed a p-value of 0.002.
- Change in knowledge related to the risk factor "red and processed meats" showed a p-value of 0.048.
- Change in knowledge related to the risk factor "being overweight or obese" showed a p-value of 0.008.
- Change in knowledge for "recommended age to start colonoscopy" showed a p-value of 0.0001.
- Change in knowledge for "Recommended age to start FIT/FOBT" showed a p-value of 0.0001.
What this means
The results indicate that the educational intervention was associated with statistically significant improvements in participant knowledge across several critical aspects of colorectal cancer risk, prevention, and screening. These findings suggest that the intervention effectively addressed key knowledge gaps, which could potentially lead to improved screening behaviors and earlier detection of colorectal cancer, particularly in rural populations.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT04414306, titled "Screen to Save 2: Rural Cancer Screening Educational Intervention", were posted on 2026-02-02 on clinicaltrials.gov.