Novel Biomarkers of Non-IgE Immediate Hypersensitivity Drug Reactions

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT07605806
Phase
PHASE1/PHASE2
Status
Recruiting
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Conditions

  • Healthy Volunteer
  • Hypersensitivity Reactions
  • Vancomycin

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Vancomycin (IV) — DRUG
    single infusion of vancomycin in healthy volunteers

Study Details

The goal of this clinical trial is to investigate biomarkers of non-IgE-mediated immediate hypersensitivity reactions during infusion of intravenous vancomycin. The main question it aims to answer is: • Identifying novel biomarkers in blood that occur during infusion reaction Participants will: * Have allergy skin testing for vancomycin * Receive an infusion of vancomycin

Key Dates

Start date
May 21, 2026
Status verified
May 2026
Primary completion
May 30, 2027
Completion
Jun 30, 2027

Study Design

Enrollment
25 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Vancomycin
    single infusion of vancomycin in healthy volunteers

Primary Outcome Measure

Serum vancomycin concentration (mg/mL) [ Time Frame: 30 minutes ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Johns Hopkins University School of MedicineBaltimoreMaryland21287-

Find similar trials in Baltimore, MD

By research site
Johns Hopkins University School of Medicine· Baltimore, MD

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