Gut Microbiome Response to Long-Haul Travel in Elite Football Players

Part of paid clinical trials in Nashville, Tennessee.

Sponsor
Sheffield Hallam University
Study ID
NCT07585474
Status
Enrolling By Invitation

Conditions

  • Immune Function
  • Microbial Composition

Eligibility Criteria

Sex
MALE
Age
18 Years - 40 Years
Healthy Volunteers
Accepted

Interventions

  • Probiotic Capsule — DRUG
    Probiotic capsule administered orally once daily for 3 weeks
  • Placebo — DRUG
    Placebo tablet, identical in appearance to probiotic, administered orally once daily for 3-4 weeks.

Study Details

The goal of this randomised control trial is to measure the gut microbiome response to long-haul travel alongside the demands of pre-season amongst elite football players. The efficacy of a probiotic in modulating the gut microbiome to mitigate the detrimental impacts of long-haul travel as well as training in the heat will also be explored. The main questions this study aims to answer are: * How is the gut microbiome of the professional football player impacted by long-haul travel during the pre-season period? * How is immune function impacted by the demands of pre-season? * Can a probiotic dietary maintain gut microbial stability in response to long-haul travel? Researchers will compare the effects of the probiotic supplement with a placebo. Participants will be required to: * Provide a faecal sample at multiple points throughout the pre-season * Provide a saliva sample at multiple points throughout the season * Consume a daily supplement which will either be a placebo or probiotic capsule

Key Dates

Start date
Jul 25, 2025
Status verified
May 2026
Primary completion
Aug 18, 2025
Completion
Aug 15, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Active Treatment Group
    All participants receive probiotic once orally for 3-4 weeks
  • Placebo Comparator: Placebo
    Participants receive matching placebo orally once daily for 3-4 weeks

Primary Outcome Measure

Gut Microbiome [ Time Frame: 3-4 weeks ]

Locations (1)

FacilityCityStateZIPSite coordinators
1 Hotel NashvilleNashvilleTennessee37203-

Find similar trials in Nashville, TN

By research site
1 Hotel Nashville· Nashville, TN

Related Studies