Connectomic Alterations Following Acute Ischemic Stroke in the MCA Territory

Part of paid clinical trials in New York, New York.

Sponsor
Northwell Health
Study ID
NCT07584681
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • MRI with connectomic sequencing — OTHER
    Resting-state functional MRI (rs-fMRI) and diffusion MRI (dMRI) sequences

Study Details

This study seeks to use safe, powerful, non-invasive computing tools, including machine learning and advanced neuroimaging analysis, to better understand how stroke affects the brain's network of connections. Using structural MRI, including diffusion-weighted imaging, this study will generate a detailed map of brain pathways to evaluate how strokes in the middle cerebral artery (MCA) territory disrupt the brain's structural networks. In the future, this approach may help physicians better predict recovery, monitor neuroplasticity, and guide rehabilitation decisions after stroke.

Key Dates

Start date
May 31, 2026
Status verified
May 2026
Primary completion
Apr 30, 2027
Completion
Apr 30, 2028

Study Design

Enrollment
10 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Other: Primary Study Group
    Arm participants will receive 3 resting-state functional MRIs (rs-fMRI) and diffusion MRIs (dMRI) prior to discharge and at 1- and 3-months post-intervention to generate functional and structural connectomes.

Primary Outcome Measure

Feasibility of using Connectomic Sequencing in Stroke Patients [ Time Frame: 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Lenox Hill HospitalNew YorkNew York10075-

Find similar trials in New York, NY

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Lenox Hill Hospital· New York, NY

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