Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease

Part of paid clinical trials in Aurora, Colorado.

Sponsor
University of Colorado, Denver
Study ID
NCT07576894
Status
Recruiting
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Conditions

  • COPD
  • Exercise
  • Exercise Training
  • Pulmonary Hypertension
  • Right Ventricular (RV) Dysfunction

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Exercise training — BEHAVIORAL
    Exercise training will include moderate-intensity interval training 3x/week.

Study Details

This study plans to learn more about heart function among individuals with chronic obstructive pulmonary disease (COPD). In particular, the investigators want to understand the different patterns of right ventricular response during rest and moderate- vs high-intensity exercise. By identifying patterns of right ventricular dysfunction, this study will help identify better treatments for patients with COPD in the future.

Key Dates

Start date
Aug 1, 2025
Status verified
May 2026
Primary completion
May 1, 2030
Completion
Aug 1, 2030

Study Design

Enrollment
60 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: COPD
    Participants will complete testing at rest and during moderate- and high-intensity exercise to identify patterns of right ventricular responses. Participants who based on baseline testing are eligible and decide to participate in the optional exercise training program will complete exercise training followed by repeat testing to determine the impact of exercise training on right ventricular dysfunction.

Primary Outcome Measure

Right ventricular contractility measured by transthoracic echocardiography [ Time Frame: Up to 1 hour ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Colorado Anschutz Medical CampusAuroraColorado80045
Lindsay Forbes, MD
[email protected]
303-724-4020

Find similar trials in Aurora, CO

By condition
COPD
By specialty
PulmonologyLung disease
By research site
University of Colorado Anschutz Medical Campus· Aurora, CO

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