100-Year Human Aging Study

Part of paid clinical trials in Boulder, Colorado.

Sponsor
Longevity Metrics, Inc.
Study ID
NCT07563777
Status
Recruiting
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Conditions

  • Activities of Daily Living
  • Aging
  • Aging Well
  • All-Cause Mortality
  • Cardiovascular Diseases
  • Cognitive Dysfunction
  • Dementia
  • Disability Physical
  • Frailty
  • Health-Related Quality of Life
  • Metabolic Syndrome
  • Mortality
  • Musculoskeletal Diseases
  • Neoplasms
  • Neuro-Degenerative Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Comprehensive Multi-System Clinical Screening — DIAGNOSTIC_TEST
    Comprehensive multi-system clinical screening battery including cardiopulmonary exercise testing, body composition assessment by DEXA, echocardiography, electrocardiography, spirometry, neurocognitive testing, sensory assessment, metabolic testing, physical examination, and detailed medical, social, occupational, and environmental history. Participants receive individualized clinical findings and investigational longevity constructs at the conclusion of screening.

Study Details

The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed and mobile clinical sites to undergo comprehensive multi-system health screening and longitudinal follow-up until death. Participants are followed to determine whether measurements taken at enrollment and repeated across the lifespan - individually and in combination - predict all-cause mortality, cause-specific mortality, incident serious disease, and functional disability. The study is designed to generate the surrogate endpoint validation data that longevity medicine currently lacks.

Key Dates

Start date
Feb 9, 2025
Status verified
Jun 2026
Primary completion
Dec 31, 2099
Completion
Dec 31, 2099

Study Design

Enrollment
1,000,000 participants (estimated)

Primary Outcome Measure

All-Cause Mortality [ Time Frame: From enrollment until death, assessed periodically, up to 100 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Longevity MetricsBoulderColorado80301
William E Brandenburg, MD
[email protected]
3035010016

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