Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot Study

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT07556406
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
55 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Optical coherence tomography — DIAGNOSTIC_TEST
    High-resolution imaging method used to evaluate the structure of the retina
  • Microperimetry — DIAGNOSTIC_TEST
    A functional test that maps retinal sensitivity by measuring how well you can detect lights in different areas of your vision.

Study Details

This study is being conducted to assess two imaging methods-central microperimetry and radial OCT (Optical Coherence Tomography)-in patients with Geographic Atrophy (GA) or those who are at risk of developing this condition. The study team is trying to determine whether these methods can provide more accurate measurements of GA progression toward the foveal center, the central part of the retina responsible for your sharpest, most detailed vision.

Key Dates

Start date
Jun 11, 2025
Status verified
Apr 2026
Primary completion
Jun 11, 2027
Completion
Jun 11, 2027

Study Design

Enrollment
80 participants (estimated)

Arms

  • Arm: Non-central geographic atrophy not being treated
    Patients with age-related macular degeneration who have geographic atrophy that does not involve the fovea.
  • Arm: Intermediate age-related macular degeneration
    Patients with intermediate age-related macular degeneration
  • Arm: Non-central geographic atrophy currently being treated
    Patients with non-central geographic atrophy from age-related macular degeneration who are currently receiving treatment for this condition.
  • Arm: Non-central geographic atrophy initiating treatment
    Patients with non-central geographic atrophy from age-related macular degeneration who will be starting to receive treatment for this condition.

Primary Outcome Measure

Geographic atrophy progression rate [ Time Frame: 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, San FranciscoSan FranciscoCalifornia94143
Jay M Stewart, MD
[email protected]
628-206-3123
Jay M Stewart, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in San Francisco, CA

By condition
Age-related macular degeneration
By specialty
OphthalmologyRetina
By research site
University of California, San Francisco· San Francisco, CA

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