Fasted vs. Fed State Exercise

Part of paid clinical trials in Fort Smith, Arkansas.

Sponsor
Arkansas Colleges of Health Education
Study ID
NCT07487090
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 59 Years
Healthy Volunteers
Accepted

Interventions

  • 16 week exercise intervention — BEHAVIORAL
    Both groups will receive a 16-week supervised aerobic exercise program progressing to 1,600 kcal of EE per wk (4 sessions/week) at moderate intensity (40-50% heart rate reserve, HRR).

Study Details

Although many medications exist for both heart disease and obesity, cost, lack of access for all people, side effects and the desire for a more natural solution have left many people seeking lifestyle treatments such as exercise. Scientists know that exercise is highly beneficial for heart health. When exercise also produces weight loss, these benefits are much improved. Although using exercise to treat or prevent heart disease / obesity is recommended, not all people respond well. Some see significant weight loss and health improvements while others see little changes. For these reasons, new strategies surrounding the use and design of an exercise program are needed. One such strategy could be performing aerobic exercise before breakfast (fasted exercise). When exercising fasted, food/energy stores are low, and one relies on stored body fat for energy. This may help heart health and weight loss. This has never been tested in a program long enough to see such changes. This study will, for the first time, assess the effects of a 16-week aerobic exercise program performed fasted compared to after eating. Outcomes will include blood fats, blood pressure, fat-burning abilities and weight loss. Starting an exercise program can also make people to eat more. This limits the success of exercise. The study will also evaluate ways fasted exercise could change eating, as it possible that fasted exercise could also cause people to eat more, which would limit weight loss and health improvements.

Key Dates

Start date
Jan 5, 2026
Status verified
Mar 2026
Primary completion
Jul 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Fasted group
    Complete all exercise sessions of intervention before breakfast- fasted at least 8 hours
  • Experimental: Fed exercise group
    Complete all exercise sessions of intervention after breakfast- within 3 hours of eating at least 300 kcal

Primary Outcome Measure

body composition [ Time Frame: Baseline (week 0) and post-intervention (week 25) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Arkansas Colleges of Health Education Research Institure Health and Wellness CenterFort SmithArkansas72916
Kyle D Flack, PhD
[email protected]
(479) 434-4019
Blake Metcalf, DCN
[email protected]
4794344003

Find similar trials in Fort Smith, AR

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Arkansas Colleges of Health Education Research Institure Health and Wellness Center· Fort Smith, AR

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