Time Restricted Feeding, Muscle, and Metabolism

Part of paid clinical trials in Fayetteville, Arkansas.

Sponsor
University of Arkansas, Fayetteville
Study ID
NCT04949451
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
25 Years - 50 Years
Healthy Volunteers
Accepted

Interventions

  • Whey protein supplement — DIETARY_SUPPLEMENT
    Participants consume whey protein at the beginning of the eating period.
  • Ketogenic aid — DIETARY_SUPPLEMENT
    Participants consume ketogenic aid upon waking.
  • Control group - time restricted feeding only — OTHER
    Time restricted feeding.

Study Details

Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.

Key Dates

Start date
Jun 13, 2021
Status verified
Aug 2025
Primary completion
Apr 30, 2025
Completion
Dec 30, 2025

Study Design

Enrollment
90 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Placebo Comparator: TRF-C
    Follows time restricted feeding protocol.
  • Experimental: TRF-P
    Follows time restricted feeding protocol, consumes protein supplement
  • Experimental: TRF-S
    Follows time restricted feeding protocol, consumes ketogenic supplement

Primary Outcome Measure

Body composition [ Time Frame: Change is being assessed at baseline and final day (day 120) of the intervention. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of ArkansasFayettevilleArkansas72704
Jamie I Baum, PhD
[email protected]
479-575-4474

Find similar trials in Fayetteville, AR

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
University of Arkansas· Fayetteville, AR

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