A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT07483203
Status
Not Yet Recruiting

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Conditions

  • Pulmonary Vascular Disease
  • Valvular Heart Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Echocardiogram — DIAGNOSTIC_TEST
    An echocardiogram will be performed during the patient's routinely scheduled right heart catheterization.

Study Details

The purpose of this study is to characterize pulmonary hemodynamic profiles, with a focus on PVR subtypes, in patients with left-sided valvular heart disease undergoing aortic or mitral valve intervention, and to identify patterns predicting reversibility of TR and RV dysfunction.

Key Dates

Start date
May 31, 2026
Status verified
Mar 2026
Primary completion
May 31, 2028
Completion
May 31, 2028

Study Design

Enrollment
600 participants (estimated)

Arms

  • Arm: Aortic Intervention
  • Arm: Mitral Intervention
  • Arm: Tricuspid intervention

Primary Outcome Measure

Tricuspid Regurgitation (TR) reduction [ Time Frame: Baseline, 12 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905-

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