Radiation to Treat Joint Damage Caused by Cancer Immunotherapy

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Chicago
Study ID
NCT07478679
Phase
PHASE1
Status
Not Yet Recruiting

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Conditions

  • Arthritis
  • Arthropathy

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Low dose radiation therapy — RADIATION
    0.5 Gy per treatment x 6 treatments, given 2-3 treatments per week over 2-3 weeks (Can be given concurrently with IO)

Study Details

This study will prospectively investigate the feasibility and safety of administering LDRT in patients with immunotherapy-induced inflammatory arthritis.

Key Dates

Start date
Aug 26, 2026
Status verified
Mar 2026
Primary completion
Sep 17, 2028
Completion
Sep 17, 2028

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Radiation treatment

Primary Outcome Measure

Radiation therapy [ Time Frame: 3 months post enrollment. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The University of Chicago Medicine Comprehensive Cancer CenterChicagoIllinois60637
Clinical Trials Intake
[email protected]
855-702-8222
Pankti Reid (PRINCIPAL_INVESTIGATOR)

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By research site
The University of Chicago Medicine Comprehensive Cancer Center· Chicago, IL

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