A Study of Brenipatide (LY3537031) in Healthy Participants With Overweight or Obesity

Part of paid clinical trials in Daytona Beach, Florida.

Sponsor
Eli Lilly and Company
Study ID
NCT07476118
Phase
PHASE1
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Brenipatide — DRUG
    Administered SC.
  • Placebo — OTHER
    Administered SC.

Study Details

The main purpose of this study is to evaluate how different dose levels of brenipatide work and how safe they are in healthy people with overweight or obesity. The study will assess the effects of different doses given as subcutaneous (under the skin) injections. Participation in this study will last about 42 weeks.

Key Dates

Start date
Mar 18, 2026
Status verified
Apr 2026
Primary completion
Feb 28, 2027
Completion
Feb 28, 2027

Study Design

Enrollment
150 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Brenipatide
    Participants will receive brenipatide subcutaneously (SC).
  • Placebo Comparator: Placebo
    Participants will receive placebo administered SC.

Primary Outcome Measure

Percent Change in Body Weight [ Time Frame: Week 1, Week 29 ]

Central Contacts

  • Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559)
    1-317-615-4559
    [email protected]
  • Physicians interested in becoming principal investigators please contact
    [email protected]

Locations (3)

FacilityCityStateZIPSite coordinators
Fortrea Clinical Research Unit - Daytona BeachDaytona BeachFlorida32117-5116
866-429-3700
Kathleen Doisy (PRINCIPAL_INVESTIGATOR)
Fortrea Clinical Research UnitDallasTexas75247
866-429-3700
Gene Voskuhl (PRINCIPAL_INVESTIGATOR)
Fortrea Clinical Research Unit Inc. - MadisonMadisonWisconsin53704
866-429-3700
Kimberly Cruz (PRINCIPAL_INVESTIGATOR)

Find similar trials in Daytona Beach, FL

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Fortrea Clinical Research Unit - Daytona Beach· Daytona Beach, FLFortrea Clinical Research Unit· Dallas, TXFortrea Clinical Research Unit Inc. - Madison· Madison, WI

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