Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series

Part of paid clinical trials in Strongsville, Ohio.

Sponsor
Reset Medical and Wellness Center
Study ID
NCT07473505
Status
Recruiting
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Conditions

  • Anxiety
  • Moral Injury
  • PTSD
  • Trauma-related Mental Health Symptoms
  • Traumatic Brain Injury

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • stellate ganglion block with 0.5% ropivacaine — PROCEDURE
    This study is distinct because it evaluates an integrative, dual-level bilateral cervical sympathetic block (BCSB), a more comprehensive autonomic intervention than the traditional unilateral SGB, specifically in Special Operations Veterans, a uniquely high-trauma, high-TBI population rarely studied. It is also the first to directly compare BCSB alone versus BCSB combined with structured integrative psychological therapy, using a prospective design with validated outcome measures, strict inclusion/exclusion criteria, and standardized FDA-approved dosing. By incorporating TBI-specific symptom tracking and applying IND-level rigor in a specialized trauma-informed clinical setting, this study fills critical gaps left by prior SGB research and offers a clearer understanding of who benefits most and why.

Study Details

This study prospectively evaluates the effects of Integrative Bilateral Cervical Sympathetic Block (BCSB) on trauma-related symptoms in Special Operations Veterans, comparing outcomes in those receiving BCSB alone versus BCSB combined with structured integrative therapy. Using standardized FDA-approved dosing, validated symptom measures, and strict safety criteria, the study aims to determine whether this dual-level autonomic intervention improves PTSD-related and TBI-related symptoms, and whether pairing the procedure with therapy enhances durability and overall clinical benefit.

Key Dates

Start date
Mar 20, 2026
Status verified
Mar 2026
Primary completion
Feb 24, 2027
Completion
Jul 1, 2027

Study Design

Enrollment
75 participants (estimated)

Arms

  • Arm: Ropivacaine Based BCSB
    This cohort consists of combat veterans participating in the RESET study to evaluate the effects of bilateral cervical sympathetic ganglion blocks (BCSB) on post-traumatic stress symptoms and suicide risk. Participants receive one procedures as a clinical intervention. Some participants may decided to access additional therapies, making BCSB an integrative model.

Primary Outcome Measure

PTSD Checklist for the DSM-5 [ Time Frame: From baseline to 7, 30, 60, 90, 180 and 270 days post BCSB procedure. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Reset Medical and Wellness CenterStrongsvilleOhio44136
Michael Louwers
[email protected]
8777373810

Find similar trials in Strongsville, OH

By condition
PTSD (post-traumatic stress disorder)
By specialty
PsychiatryMental healthBehavioral health
By research site
Reset Medical and Wellness Center· Strongsville, OH

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