Vascular Intervention Strategies Trial for Alzheimer's

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of Southern California
Study ID
NCT07447206
Phase
PHASE2
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Angiotensin Receptor Blockers (ARBs) — DRUG
    Participants receive pharmacist-led management of vascular risk factors over a six-month period. This includes blood pressure management with angiotensin receptor blockers (ARBs).
  • Hydrophilic Statins or Non-Statin Alternative — DRUG
    Participants receive pharmacist-led management of vascular risk factors over a six-month period. This includes cholesterol management with hydrophilic statins or a non-statin alternative if statins are not appropriate.

Study Details

The proposed pharmacist-led study is a feasibility pilot trial for the management of vascular risk factors of hypertension and hypercholesterolemia in 10 APOE ε4 carriers, 50-75, at-risk for dementia. All participants will receive angiotensin receptor blockers (ARBs) for high blood pressure, and hydrophilic statins (or a non-statin alternative) for high cholesterol over a six-month period.

Key Dates

Start date
May 31, 2026
Status verified
Apr 2026
Primary completion
Jun 30, 2027
Completion
Jun 30, 2028

Study Design

Enrollment
10 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Pharmacist-Led Vascular Risk Factor Management
    Participants receive pharmacist-led management of hypertension and hypercholesterolemia using angiotensin receptor blockers and hydrophilic statins (or non-statin alternatives) over six months.

Primary Outcome Measure

Blood Pressure Control [ Time Frame: Baseline to 6 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Clinical Sciences Building (CSC)Los AngelesCalifornia90033-

Find similar trials in Los Angeles, CA

By condition
Hypertension (high blood pressure)
By specialty
CardiologyHeart disease
By research site
Clinical Sciences Building (CSC)· Los Angeles, CA

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