Dental Plaque Prevention Efficacy of a Stannous Fluoride Toothpaste

Part of paid clinical trials in Fort Wayne, Indiana.

Sponsor
Church & Dwight Company, Inc.
Study ID
NCT07419737
Status
Completed

Conditions

  • Dental Plaque

Eligibility Criteria

Sex
ALL
Age
18 Years - 69 Years
Healthy Volunteers
Accepted

Interventions

  • Stannous Fluoride Toothpaste (SnF) — DRUG
    Test toothpaste (0.454% SnF)
  • Sodium Fluoride Dentifrice — DRUG
    Comparator toothpaste (0.243% NaF)

Study Details

This randomized, stratified, double-blind, two-cell parallel clinical study evaluated the dental plaque prevention efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste following a professional dental prophylaxis. Adult subjects brushed twice daily for 14 days with their assigned dentifrice. Plaque was assessed using the Lobene-Soparkar modification of the Turesky Modification of the Quigley-Hein Plaque Index at baseline, Day 1, and Day 14 following periods of oral hygiene abstention.

Key Dates

Start date
Oct 16, 2024
Status verified
Feb 2026
Primary completion
Dec 4, 2024
Completion
Dec 4, 2024

Study Design

Enrollment
91 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Other: Sodium Fluoride Control Dentifrice
    Dentifrice containing sodium fluoride, serving as the control comparator.
  • Experimental: Stannous Fluoride Toothpaste
    Dentifrice containing stannous fluoride evaluated for plaque prevention compared to sodium fluoride control.

Primary Outcome Measure

Whole-Mouth Dental Plaque Score (Turesky Modified Quigley-Hein Index) [ Time Frame: Day 14 (12 hours post-brushing following 14 days of twice-daily use) ]

Locations (1)

FacilityCityStateZIPSite coordinators
Salus Research, Inc.Fort WayneIndiana46825-

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Salus Research, Inc.· Fort Wayne, IN

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