Ketogenic Diet to Reduce Osteoarthritis Pain in MCI

Part of paid clinical trials in Fairway, Kansas.

Sponsor
University of Kansas Medical Center
Study ID
NCT07417891
Status
Not Yet Recruiting

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Conditions

  • Dementia
  • MCI
  • Mild Cognitive Impairment
  • Mild Cognitive Impairment (MCI)
  • Osteoarthritis
  • Osteoarthritis (OA) of the Hip
  • Osteoarthritis (OA) of the Knee
  • Osteoarthritis (OA) of the Shoulder

Eligibility Criteria

Sex
ALL
Age
55 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Well-formulated ketogenic diet — OTHER
    This is a very low carbohydrate eating pattern that is higher in fat with adequate protein. This approach focuses on a nutrient dense, whole foods approach to a ketogenic diet and recommends 4-6 servings of non-starchy vegetables per day, 1/4 cup of berries per day, daily intake of nuts/seeds, fatty fish 2-3 times per week, and an emphasis on healthy fats like avocado, nuts, and olive oil.

Study Details

Osteoarthritis and mild cognitive impairment are common conditions that share underlying biological processes related to metabolism and inflammation. This study will examine whether a well-formulated ketogenic diet influences pain, physical function, and cognitive outcomes in adults with osteoarthritis and mild cognitive impairment. Participants will follow a supervised ketogenic dietary intervention, with assessments conducted before and after the intervention to evaluate changes in symptoms and related biological markers. The goal of this study is to better understand shared mechanisms between joint pain and cognitive health and to explore whether a ketogenic dietary approach may support symptom management in these populations.

Key Dates

Start date
Jun 1, 2026
Status verified
Apr 2026
Primary completion
Apr 1, 2027
Completion
Jun 1, 2027

Study Design

Enrollment
10 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Well-formulated ketogenic diet
    This is a dietary intervention that is very low carbohydrate, higher healthy fats, and adequate protein.

Primary Outcome Measure

Pain intensity and pain interference using a Visual Analog Scale [ Time Frame: From enrollment to the end of treatment at 8 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Kansas Medical CenterFairwayKansas66205
Jessica Keller, PhD, RDN
[email protected]
913-609-5915

Find similar trials in Fairway, KS

By condition
Osteoarthritis (other)
By specialty
OrthopedicsMusculoskeletal disorders
By research site
University of Kansas Medical Center· Fairway, KS

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