Speech Learning and Speech Production in Parkinson's Disease

Part of paid clinical trials in Buffalo, New York.

Sponsor
State University of New York at Buffalo
Study ID
NCT07403539
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
45 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Intensity learning — BEHAVIORAL
    Participants will be asked to pair sentences that vary in their sound intensity to one of three colored squares (red, yellow, or blue)
  • Intensity discrimination — BEHAVIORAL
    Participants will hear two sentences that are either the same or different in their sound intensity and will be asked to indicate whether the sentences were of the same or different intensities
  • Rate learning — BEHAVIORAL
    Participants will be asked to pair sentences that vary in their spoken rate to one of three colored squares (red, yellow, or blue)
  • Rate discrimination — BEHAVIORAL
    Participants will hear two sentences that are either the same or different in their spoken rate and will be asked to indicate whether the sentences were of the same or different rates

Study Details

Parkinson's disease, a common movement disorder that results from a breakdown in the brain, often leads to challenges with talking, but less is known about the relationship between difficulties with talking and difficulties with learning to understand speech. By linking these two abilities in individuals with Parkinson's disease using a precision medicine approach, this project seeks to build a basis for new therapies that help people with Parkinson's disease both understand better and speak more clearly.

Key Dates

Start date
Jan 27, 2026
Status verified
Feb 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
50 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Learning and Discrimination
    Behavioral interventions will be administered, including speech intensity learning, speech intensity discrimination, speech rate learning, and speech rate discrimination

Primary Outcome Measure

Mean dB SPL [ Time Frame: Day 1 ]

Locations (1)

FacilityCityStateZIPSite coordinators
State University of New York at BuffaloBuffaloNew York14214
Jordana Maisel
1 (716) 829-5902

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