Intra-aortic Balloon Counterpulsation (IABC) Compliance

Part of paid clinical trials in Philadelphia, Pennsylvania.

Sponsor
Thomas Jefferson University
Study ID
NCT07402018
Status
Recruiting
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Conditions

  • Cardiogenic Shock
  • IABC Procedure
  • Intraaortic Balloon Counterpulsation (IABC)

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

The investigators intend to study how baseline arterial compliance (as defined by stroke volume/pulse pressure) influences the clinical success of intraaortic balloon counterpulsation (IABC) in patients with cardiogenic shock (CS). The investigators aim to compare clinical outcomes in CS patients requiring IABC with normal compliance versus low compliance. The study will enroll patients undergoing IABC that are clinically indicated. Baseline hemodynamic measurements will be obtained and then patients would be stratified based on their compliance. Post IABC, serial hemodynamic measurements will be obtained and compared between groups. Patients will continue to be followed longitudinally until the IABC has been discontinued for any reason. The proposed study will yield results that will aid in developing a larger clinical trial and ultimately assist clinicians in determining if IABC is appropriate therapy for patients in cardiogenic shock.

Key Dates

Start date
Jan 27, 2026
Status verified
Nov 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
20 participants (estimated)

Primary Outcome Measure

Cardiac Output (L/min) [ Time Frame: 24 hours ]

Central Contacts

  • Elizabeth R Westburg, MS
    215-955-2050
    [email protected]
  • Matthew S Delfiner, DO, MS
    215-955-2050

Locations (1)

FacilityCityStateZIPSite coordinators
Thomas Jefferson University HospitalPhiladelphiaPennsylvania19107
Elizabeth Westburg, MS
[email protected]
267-872-1871
Matthew S Delfiner, DO, MS (PRINCIPAL_INVESTIGATOR)

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Thomas Jefferson University Hospital· Philadelphia, PA

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