Low Versus High Load Training and Parkinson's Disease

Part of paid clinical trials in Coral Gables, Florida.

Sponsor
University of Miami
Study ID
NCT07378813
Status
Recruiting
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Conditions

  • Activity, Motor

Eligibility Criteria

Sex
ALL
Age
50 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • Low-Load Resistance Training — BEHAVIORAL
    Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using three sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.
  • High-Load Resistance Training — BEHAVIORAL
    Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using four sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.

Study Details

This study will compare the effects of high-load resistance training to low-load resistance training, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.

Key Dates

Start date
Jan 30, 2026
Status verified
Jan 2026
Primary completion
May 30, 2027
Completion
May 30, 2027

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Low-Load Resistance Training
    Participants will receive low-load resistance training, twice per week for at least 24 sessions for up to 12 weeks.
  • Active Comparator: High-Load Resistance Training
    Participants will receive high-load resistance training, twice per week for at least 24 sessions for up to 12 weeks.

Primary Outcome Measure

Change in neuromuscular performance as measured by 1-repetition maximum (1RM) [ Time Frame: [Time Frame: Baseline, 12 weeks] ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Laboratory of Neruomuscular Research and Active AgingCoral GablesFlorida33147
Ethan Elway, MS
[email protected]
305-284-4173
Joseph F. Signorile, PhD
[email protected]
3052843105
Joseph F. Signorile, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
Laboratory of Neruomuscular Research and Active Aging· Coral Gables, FL

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