Hormones, Outcomes, and Pain Pathways in Exercise Study

Part of paid clinical trials in Houston, Texas.

Sponsor
University of Houston
Study ID
NCT07579182
Phase
PHASE1
Status
Recruiting
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Conditions

  • Activity, Motor
  • Back Pain
  • Back Pain, Low
  • Breast Pain
  • Chest Pain
  • Gonadal Steroid Hormones
  • Healthy Aging
  • Inflammation
  • Mastalgia
  • Neck Pain
  • Neuromuscular Manifestations
  • Neuronal Plasticity
  • Weight, Body

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

  • Interventional Sports bra — OTHER
    This study involves use of observation and analysis of behavior in assessing breast motion and associated health outcomes while using a provided interventional sports bra of participant choice (Bounceless bra or Shefit Ultimate bra) for 3 months.

Study Details

The goal of the proposed project is to evaluate a mechanical intervention (sports bras designed specifically for full busted women) to alleviate neck, shoulder, arm, and back pain in full-busted women and investigate the contribution of non-mechanical pathways associated with this type of pain in women. Specifically, the investigators will investigate how sex-hormones, inflammation, and remapping of specific regions of the brain contribute to the manifestation of neck, shoulder, arm, and back pain in full-busted women across the lifespan.

Key Dates

Start date
May 17, 2026
Status verified
May 2026
Primary completion
Jun 30, 2029
Completion
Sep 30, 2029

Study Design

Enrollment
140 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • No Intervention: Control
    Women with bra cup sizes A - C. Control group will undergo measurement of kinematic and kinetic data during physical activities at baseline. Study questionnaires, pain measures, body composition, brain activity, and blood-based biomarkers will be collected at baseline. Physical activity will be tracked via smartwatch for 3 months after baseline.
  • Experimental: Interventional Sports Bra
    Women with bra cup sizes D - I. Intervention group will undergo measurement of kinematic and kinetic data during physical activities at baseline and 3 months after receiving their interventional sports bras. Study questionnaires, pain measures, body composition, brain activity, and blood-based biomarkers will be collected at baseline and 3 months after receiving the interventional sports bras. Physical activity will be tracked via smartwatch for 3 months after baseline.

Primary Outcome Measure

Pain Measures [ Time Frame: Baseline and 3 months after baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of HoustonHoustonTexas77204
Stacey L Gorniak, PhD
[email protected]
713-743-4802
Stacey L Gorniak, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
University of Houston· Houston, TX

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