Low-Intensity Focused Ultrasound Neuromodulation for Epilepsy

Part of paid clinical trials in Roanoke, Virginia.

Sponsor
Carilion Clinic
Study ID
NCT07353918
Status
Enrolling By Invitation

Conditions

  • Epilepsy (Treatment Refractory)
  • Epilepsy Comorbidities

Eligibility Criteria

Sex
ALL
Age
18 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • Low-intensity Focused Ultrasound — DEVICE
    focused ultrasound transducer.
  • Sham — DEVICE
    Sham application of LIFU - energy blocked. Targeted to the same target as intervention.

Study Details

This study is an invite only study looking at the effects of Low-Intensity Focused Ultrasound (LIFU) on epilepsy patients with implanted electrodes under the care of Dr. Shah.

Key Dates

Start date
Oct 13, 2025
Status verified
Jan 2026
Primary completion
Dec 31, 2027
Completion
May 31, 2028

Study Design

Enrollment
6 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: LIFU- real
    Low-intensity focused ultrasound will be applied to the entorhinal cortex in a pre/post design.
  • Sham Comparator: LIFU - Sham
    Sham Low-intensity focused ultrasound will be applied to the entorhinal cortex in a pre/post design.

Primary Outcome Measure

Seizure Frequency [ Time Frame: 6 months past their final research study visit ]

Locations (1)

FacilityCityStateZIPSite coordinators
Fralin Biomedical Research Institute at VTCRoanokeVirginia24016-

Find similar trials in Roanoke, VA

By research site
Fralin Biomedical Research Institute at VTC· Roanoke, VA

Related Studies