The Use of Rhythmic Light Therapy in Mild Cognitive Impairment

Part of paid clinical trials in New York, New York.

Sponsor
Icahn School of Medicine at Mount Sinai
Study ID
NCT07318038
Status
Recruiting
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Conditions

  • Mild Cognitive Impairment

Eligibility Criteria

Sex
ALL
Age
55 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Flickering Light — DEVICE
    Red Flickering Light programed to three different visual stimulations

Study Details

In this within-subjects, crossover study, participants will undergo Electroencephalogram (EEG) recordings before, during, and after each of three 1-hour sessions. All participants will experience all three conditions: (1) dual-frequency visual (10 and 40 Hz), (2) single-frequency visual (40 Hz), and (3) non-rhythmic stimulation. EEG spectral power and amplitude coupling will be analyzed to determine whether stimulation-induced increases in alpha-gamma neural synchrony translate to improvements in cognitive performance.

Key Dates

Start date
Dec 8, 2025
Status verified
Dec 2025
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: Dual frequency flickering light
    Light flickering with 10 Hz + 40 Hz visual stimulation
  • Experimental: Single frequency flickering light
    Light flickering with 10 Hz visual stimulation
  • Placebo Comparator: non-rhythmic flickering light
    Light flickering with random visual stimulation

Primary Outcome Measure

EEG-based neural synchrony [ Time Frame: 5 minute EEG recording will be done at start, middle and end of each one-hour session, each session separated by one week ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Icahn School of Medicine at Mount SinaiNew YorkNew York10029
Barbara Plitnick
[email protected]
518-242-4603
Mariana Figueiro (PRINCIPAL_INVESTIGATOR)

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Icahn School of Medicine at Mount Sinai· New York, NY

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