Autoimmune Features of Neurodegenerative Disorders

Part of paid clinical trials in New York, New York.

Sponsor
Columbia University
Study ID
NCT04239079
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
55 Years - 90 Years
Healthy Volunteers
Accepted

Study Details

This study is being conducted to better understand the role of inflammation in Parkinson's disease (PD) and Alzheimer's disease (AD). The investigators plan to recruit 30 PD, 30 AD/Amnestic Mild Cognitive Impairment (aMCI), and 60 age matched healthy controls in this study to study the role of immune response in PD and AD. The study involves up to two study visits involving brief questionnaires and blood draw of up to 250cc (approximately 17 tablespoons) to be collected. More ways to participate, including 1) smaller amount blood donation (up to 100cc per visit for 1-2 visits); and 2) participation via tele-visit and mobile phlebotomy visits (blood donation up to 50cc, \~5 tubes, by a certified mobile phlebotomist at home/location of choice) now available.

Key Dates

Start date
May 1, 2019
Status verified
Aug 2025
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
120 participants (estimated)

Arms

  • Arm: PD and Controls
    50% of the participants will be healthy controls and 50% will be patients diagnosed with Parkinson's disease
  • Arm: AD/aMCI and Controls
    50% of the participants will be healthy controls and 50% will be patients diagnosed with Alzheimer's disease or Amnestic Mild Cognitive Impairment (aMCI)

Primary Outcome Measure

Percentage of subjects with T-cell immune response [ Time Frame: Week 1-2 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Columbia University Medical CenterNew YorkNew York10032
Kim Tran
[email protected]
646-774-5023

Find similar trials in New York, NY

By condition
Alzheimer's diseaseParkinson's disease
By specialty
NeurologyDementia careBrain disordersGeriatrics
By research site
Columbia University Medical Center· New York, NY

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