Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients

Part of paid clinical trials in St Louis, Missouri.

Sponsor
Washington University School of Medicine
Study ID
NCT07313592
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - 30 Years
Healthy Volunteers
Not accepted

Interventions

  • ChromoSeq® assay testing — DEVICE
    Bone marrow and/or peripheral blood sample will be collected and ChromoSeq® assay testing will be completed.

Study Details

This is a prospective specimen collection study evaluating the feasibility of using the ChromoSeq® assay for upfront classification in a real-time clinical setting of pediatric and young adult acute lymphoid leukemia (ALL) patients. Sixty patients will undergo collections of bone marrow and/or peripheral blood for the ChromoSeq® assay at time of initial workup, and the patients will then be followed for clinical outcomes for up to 65 months.

Key Dates

Start date
Jun 3, 2026
Status verified
Jun 2026
Primary completion
Jul 15, 2028
Completion
Jul 15, 2028

Study Design

Enrollment
60 participants (estimated)

Arms

  • Arm: Child and Young Adult acute lymphoid leukemia (ALL) patients
    At time of initial workup, patients will undergo bone marrow and/or peripheral blood collection for ChromoSeq® (requires 1 mL of peripheral blood or bone marrow aspirate).

Primary Outcome Measure

Rate of success of ChromoSeq® [ Time Frame: Time of specimen collection to completion of results (total estimated time is 15 days) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Washington University School of Medicine/St. Louis Children's HospitalSt LouisMissouri63110
Margaret Ferris, MD, PhD
[email protected]
314-454-6018
Margaret Ferris, MD, PhD (PRINCIPAL_INVESTIGATOR)
Feng Gao, PhD (SUB_INVESTIGATOR)

Find similar trials in St Louis, MO

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By research site
Washington University School of Medicine/St. Louis Children's Hospital· St Louis, MO

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