Halt Aging in Survivors of Blood Cancers

Part of paid clinical trials in Omaha, Nebraska.

Sponsor
University of Nebraska
Study ID
NCT07292272
Phase
PHASE2
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Behavioral Coaching Intervention — BEHAVIORAL
    Intervention arm incorporating virtually supervised moderate-intensity aerobic exercise and behavioral intervention/coaching to improve adherence
  • Virtual Exercise Platform — BEHAVIORAL
    Access to a virtual exercise platform that provides exercise classes and educational sessions for older survivors of blood cancer

Study Details

Older survivors of blood cancer are at a high risk of accelerated biological aging, which increases their risk of developing multiple aging-related conditions. Whereas physical exercise can improve overall health, older cancer survivors do not meet the recommended physical activity, highlighting the need to develop behavioral interventions to increase adherence. Several other knowledge gaps exist to implement exercise interventions in older survivors of blood cancer; the dose and duration of exercise necessary to slow biological aging in older blood cancer survivors remain unknown. To bridge these gaps in knowledge, we have designed a Phase 2 randomized control trial to test the effects of behavioral and exercise interventions on various outcomes.

Key Dates

Start date
Apr 9, 2026
Status verified
Dec 2025
Primary completion
Mar 25, 2032
Completion
Mar 25, 2033

Study Design

Enrollment
180 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: Intervention Arm: Exercise + Behavioral Coaching
    Intervention arm incorporating virtually supervised moderate-intensity aerobic exercise and behavioral intervention/coaching to improve adherence
  • Active Comparator: Enhanced Usual Care-Virtual Gym
    Participants will receive access to a virtual exercise platform, and educational sessions but will not receive behavioral coaching

Primary Outcome Measure

Percentage of participants who adhered to the exercise regimen at 6-months post enrollment. [ Time Frame: 6 Months from start of program ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Nebraska Medical CenterOmahaNebraska68008
IIT Office IIT Office
[email protected]
402-559-4596
Vijaya Bhatt, MBBS (PRINCIPAL_INVESTIGATOR)

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