The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT07284082
Status
Recruiting
Apply to this trial

Conditions

  • Body Composition
  • Cardiovascular (CV) Risk
  • Carotid Arteriosclerosis
  • HIV
  • Menopause

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Whole body MRI — DIAGNOSTIC_TEST
    Whole body MRI will be performed as part of a study protocol

Study Details

Menopause is associated with the acceleration of many comorbidities, including cardiovascular disease. Whether HIV and menopause together increase cardiovascular disease risk is a key knowledge gap. The goal of this observational study is to address this knowledge gap by looking at the role of menopause on cardiovascular disease risk factors such as insulin resistance, hypertension, hyperlipidemia, and carotid atherosclerosis using previously collected data. The investigators will look at underlying causes for cardiovascular diseases worsening in menopausal women with HIV by looking at the role of increased inflammation in the body and whether this is altered by weight. The investigators achieve this by enrolling participants who are willing to undergo a whole body MRI.

Key Dates

Start date
Apr 17, 2026
Status verified
Apr 2026
Primary completion
Mar 1, 2030
Completion
Mar 1, 2030

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: MACS-WIHS Combined Cohort Study

Primary Outcome Measure

Markers of immune activation and inflammation [ Time Frame: These markers will be measured from blood work collected at the scheduled study visit [Day 1] close to the time of MRI and thus will be collected at only one time point. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, San FranciscoSan FranciscoCalifornia94110
Rebecca A Abelman, MD
[email protected]
415-223-4810

Find similar trials in San Francisco, CA

By condition
HIVMenopause
By specialty
Infectious diseaseWomen's healthFertility
By research site
University of California, San Francisco· San Francisco, CA

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