Intercostal Cryoanalgesia in Double Lung Transplant Recipients

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of California, Los Angeles
Study ID
NCT07281118
Status
Recruiting
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Conditions

  • Post-operative Pain Management

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Atricure CryoSPHERE MAX Probe — DEVICE
    Patients will be treated intra-operatively with Atricure CryoSPHERE MAX Probe to 2 intercostal spaces above and below the thoracotomy incision for 1 minutes for each application during their double lung transplant procedure.

Study Details

This study is testing a new way to help manage pain after a double lung transplant. Instead of relying only on strong pain medicines like opioids, doctors will use a cold-therapy probe during surgery to help numb the nerves near the incision. Researchers want to see if this method can reduce the need for opioids and improve recovery.

Key Dates

Start date
Dec 16, 2025
Status verified
Mar 2026
Primary completion
Nov 24, 2027
Completion
Nov 24, 2027

Study Design

Enrollment
148 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: Treatment Arm
    Patients will be treated intra-operatively with Atricure CryoSPHERE MAX Probe to 2
  • No Intervention: Usual Care
    No treatment intra-operatively

Primary Outcome Measure

Total opioid use (oral morphine equivalents) [ Time Frame: 1 year ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
University of California Los AngelesLos AngelesCalifornia90095
Steven Stokes
[email protected]
310-794-206-7436
Jenny Lester, MPH
[email protected]
310-794-9728
Abbas Ardehali, MD (PRINCIPAL_INVESTIGATOR)
University of California San FranciscoSan FranciscoCalifornia94143-
Baylor UniversityWacoTexas76706-

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