Pollution Intervention to Impact Kids Asthma Study

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT07261423
Status
Recruiting
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Conditions

  • Air Pollution, Risk Reduction Behaviors
  • Asthma Control
  • Asthma Exacerbation
  • Childhood Asthma

Eligibility Criteria

Sex
ALL
Age
8 Years - 17 Years
Healthy Volunteers
Not accepted

Interventions

  • EPA-AQI — BEHAVIORAL
    The EPA-AQI group will receive standardized outdoor air pollution education, standardized AQI education, instructions for AQI usage, and an asthma action plan containing information specific for the EPA-AQI, and will demonstrate the ability to navigate to the EPA-AQI via smartphone app or website.
  • Commerical-AQI — BEHAVIORAL
    The commercial-AQI group will receive standardized AQI education, instructions for commercial-AQI usage, and an asthma action plan containing information specific for the commercial-AQI, and will demonstrate the ability to navigate to the commercial-AQI via smartphone or website.
  • Education and plan — BEHAVIORAL
    Standardized outdoor air pollution education and standard asthma action plan

Study Details

The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are: * Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes over time? * Are there changes in nasal gene expression in children with asthma who report they are more sensitive to outdoor air pollution? Researchers will compare EPA-AQI and the commercial-AQI groups to a control group to either AQI works to improve asthma. Participants will: * Receive standardized outdoor air pollution education and an asthma action plan * Provide nose and blood specimens * Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person.

Key Dates

Start date
Feb 24, 2026
Status verified
Feb 2026
Primary completion
Jan 31, 2030
Completion
Jan 31, 2030

Study Design

Enrollment
351 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Control (Standard outdoor air pollution education + asthma action plan)
    Control
  • Experimental: EPA-AQI (Education+ plan + EPA-AQI)
    EPA-AQI
  • Experimental: Commercial-AQI (Education+ plan + commercial-AQI)
    Commercial-AQI

Primary Outcome Measure

Change in asthma control scores, over-time, between groups [ Time Frame: Baseline through 48 weeks, measured at 4 week intervals ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UPMC Children's Hospital of PittsburghPittsburghPennsylvania15224-

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By research site
UPMC Children's Hospital of Pittsburgh· Pittsburgh, PA

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