The Impact of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.

Part of paid clinical trials in Columbus, Ohio.

Sponsor
Ohio State University
Study ID
NCT07239219
Status
Recruiting
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Conditions

  • Antibiotic
  • Catheter Infection
  • Urinary Tract Infection

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • 0.05% Chlorhexidine Gluconate — OTHER
    0.05% CHG is instilled into the bladder prior to trial of void.
  • Normal Saline — OTHER
    Bladder is back filled with normal saline.

Study Details

Given the high burden of post-catheter removal UTIs, this study aims to evaluate Irrisept instillation as a non-antibiotic intervention to reduce infection rates. By comparing Irrisept to saline irrigation, the study will provide critical insights into the efficacy of antiseptic bladder irrigation in preventing UTIs while minimizing antibiotic use. If successful, this approach could lead to new clinical guidelines for catheter removal protocols, improving patient outcomes and reducing healthcare costs.

Key Dates

Start date
Dec 31, 2025
Status verified
Nov 2025
Primary completion
Jan 1, 2028
Completion
Jan 1, 2028

Study Design

Enrollment
300 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Active Comparator: Control
    Standard of care
  • Experimental: Experimental
    Experimental

Primary Outcome Measure

Urinary tract infection [ Time Frame: 30 days ]

Locations (1)

FacilityCityStateZIPSite coordinators
The Ohio State UniversityColumbusOhio43212-3153
Hiren Patel, MD, PhD
[email protected]
6142938155

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By research site
The Ohio State University· Columbus, OH

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