Conventional Ultrafiltration Versus Dilutional Ultrafiltration in Pediatric CPB Patients

Part of paid clinical trials in Akron, Ohio.

Sponsor
Akron Children's Hospital
Study ID
NCT07221630
Status
Not Yet Recruiting

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Conditions

  • Systemic Inflammatory Response Syndrome

Eligibility Criteria

Sex
ALL
Age
1 Day - 5 Years
Healthy Volunteers
Accepted

Study Details

The investigators will be comparing two different filtration methods on cardiopulmonary bypass for pediatric heart surgery patients. Three blood tests will be taken from the patient to compare which filtration method is better at decreasing post-cardiopulmonary bypass inflammation caused by the heart-lung machine.

Key Dates

Start date
Jan 1, 2026
Status verified
Oct 2025
Primary completion
Dec 31, 2026
Completion
Jan 2, 2027

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: Conventional ultrafiltration Group
    Conventional ultrafiltration will only have excess effluent removed during cardiopulmonary bypass.
  • Arm: Dilutional ultrafiltration Group
    Dilutional ultrafiltration will have continuous removal of effluent and replacement of this fluid with Plasmalyte.

Primary Outcome Measure

C-Reactive Protein outcome measure concentration in mg/dL [ Time Frame: Baseline measurement ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Akron Children's HospitalAkronOhio44308-

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Akron Children's Hospital· Akron, OH

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