Rutgers University Study of the Genetics of Pulmonary Hypertension

Part of paid clinical trials in Piscataway, New Jersey.

Sponsor
Rutgers, The State University of New Jersey
Study ID
NCT07217522
Status
Recruiting

Conditions

  • Pulmonary Arterial Hypertension
  • Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
  • Pulmonary Arterial Hypertension Associated With Connective Tissue Disease
  • Pulmonary Arterial Hypertension Associated With Connective Tissue Disease (Disorder)
  • Pulmonary Arterial Hypertension Associated With Schistosomiasis (Disorder)
  • Pulmonary Arterial Hypertension of Congenital Heart Disease
  • Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension
  • Pulmonary Hypertension

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Saliva sample — GENETIC
    Saliva sample is sent via prepaid US Mail for DNA extraction
  • Health surveys — OTHER
    Health surveys are filled out online in the study portal.

Study Details

The goal of this observational study is to learn more about how genes impact the risk of pulmonary hypertension. Anyone 18 or older living in the US is eligible, and a diagnosis of PH is NOT required. Study participation is online, and it takes about 20 minutes to complete health surveys and request a saliva collection kit sent through US mail. In return, study participants may opt to receive information about their genetic ancestry at no cost.

Key Dates

Start date
Aug 23, 2025
Status verified
Oct 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
10,000 participants (estimated)

Arms

  • Arm: Pulmonary hypertension cases
    Study participants who have been diagnosed with any form of pulmonary hypertension, either currently or in the past.
  • Arm: Pulmonary hypertension controls
    Study participants who have not been diagnosed with any form of pulmonary hypertension, either currently or in the past.

Primary Outcome Measure

Genetic risk variants associated with pulmonary hypertension [ Time Frame: 2 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Rutgers University, Piscataway, New Jersey 08854PiscatawayNew Jersey08854
Tara Matise, Ph.D.
848-445-3125
Tara Matise, Ph.D. (PRINCIPAL_INVESTIGATOR)

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