Investigation of Dysynchrony in Patients With Pulmonary Hypertension

Part of paid clinical trials in Stanford, California.

Sponsor
Stanford University
Study ID
NCT01571700
Status
Enrolling By Invitation

Conditions

  • Pulmonary Hypertension

Eligibility Criteria

Sex
ALL
Age
5 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Catheterization Pacing — PROCEDURE
    The second part of the study will include patients with pulmonary hypertension \>5 who are scheduled for a cardiac catheterization for clinical reasons. We will at the conclusion of the routine catheterization, place two pacing catheters within the right atrium and right ventricle and pace the heart at a rate approximately 10% higher than sinus rhythm for 5 minutes. We will then measure dP/dT max in the ventricles, blood pressure and cardiac output using a Fick equation to assess hemodynamics. We will repeat this 3 times using different sites in the right ventricle while simultaneously obtaining echoes to assess mechanical synchrony.

Study Details

The purpose of the study is to determine whether patients with pulmonary hypertension (PH) have dysynchrony, and if so whether it is electrical or mechanical. Once this has been determined, during a catheterization the investigators will test if pacing the heart improves blood circulation.

Key Dates

Start date
Sep 30, 2006
Status verified
Dec 2024
Primary completion
Dec 31, 2029
Completion
Dec 31, 2029

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: Study
    Patients with pulmonary hypertension.
  • Arm: Control
    ASD patients or patients with normal hearts

Primary Outcome Measure

Electrical or Mechanical Dysynchrony [ Time Frame: Open ]

Locations (1)

FacilityCityStateZIPSite coordinators
Stanford HospitalStanfordCalifornia94305-

Find similar trials in Stanford, CA

By research site
Stanford Hospital· Stanford, CA

Related Studies